Association of british neurologists

SPRING MEETING, 30 March – 1 April 2005 at Queen’s University, Belfast

Wednesday 30 March 2005

Committee Meetings
Meeting of Clinical Directors and Lead Clinicians
Afternoon Session 1

Introduction and Welcome: Dr Stanley Hawkins

Topic: Structure of neurological care

Dr J Morrow
Sue Barrow, Associate Programme Director Email triage for new neurological outpatient referrals: what the customers think The ability of a nurse specialist to diagnose simple headache disorders compared with Afternoon Session 2
Topic: Movement disorders
Chairman: Professor C Kennard

Could analysis of ocular fixation improve the clinical diagnosis of Parkinsonism? Levodopa acutely improves alertness in Parkinsonism The Royal College and the Specialities: a special relationship Neurological conditions and their co-morbidities
Satellite Symposium, sponsored by Pfizer
Common mechanisms, common modulation: neuropathic pain, epilepsy and their co- Psychiatric and behavioural co-morbidities in epilepsy Co-morbidities in neuropathic pain: a balancing act Chair round up & questions and answers followed by Dinner for Symposium delegates organized by Pfizer Thursday 31 March 2005

Morning Session 1
Topic: Neuromuscular, eye & stroke disorders
Chairman: Professor DW Chadwick

Carotid stenting techniques have evolved since CAVATAS, but have they had an impact on peri-operative morbidity? Does the Sheffield stenting register provide a clue? The Third International Stroke Trial (IST-3). Thrombolysis for acute ischaemic stroke Neuromyelitis optica in the United Kingdom Facial involvement in MuSK antibody positive myasthenia gravis Treating the untreatable: exercise-induced stem cell activation as a novel treatment
Morning Session 2
Topic: Epilepsy & miscellaneous
Chairman: Dr PEM Smith
Management of epilepsy in the community: an irish general practitioner's perspective Imaging the neocortex in epilepsy with advanced magnetic resonance imaging Clinical' 1.5 Tesla and 'specialist' 3 Tesla magnetic resonance imaging in presurgical Can we predict malignant transformation in low-grade gliomas by measuring growth Usefulness of investigation in a first seizure clinic No more neurophobia: making neurology teaching accessible to medical students Outsourcing neurology night-time cover using intercontinental telemedicine Professor Rory Collins, University of Oxford
Afternoon Session 1
Chairman: Dr V Patterson

Heroes and hooligans: sodium channels and their many roles in neurological disease Professor Stephen Waxman, Yale University School of Medicine, USA
Afternoon Session 2

Steam Train departs from Botanic Station Reception and Dinner, Ulster Folk & Transport Museum Friday 1 April 2005
Morning Session 1
Topic: Multiple sclerosis & imaging
Chairman: Dr DE Bateman

Spinal cord atrophy in multiple sclerosis is due to white matter volume loss A cannabis-based medicine (Savitex) has sustained efficacy in the treatment of An audit of the use of modafinil in clinical practice for the treatment of fatigue in Fifty years of epidemiological studies of multiple sclerosis in Northern Ireland A genomic map of the candidate susceptibility loci of multiple sclerosis in Northern Trends in survival and cause of death in patients with multiple sclerosis in Northern Multi-nodal magnetic resonance imaging and spectroscopy in normal pressure
Morning Session 2
Topic: Dementia
Chairman: Dr SA Hawkins
Two simple questions in the identification of dementia Brain biopsy in dementia: a review of 90 consecutive cases from Queen Square Tonsil biopsy in the investigation of suspected variant Creutzfeldt-Jakob disease: Department of Microbiology, Queen’s University, Belfast
Afternoon Session
Topic: Stroke

Chairman: Professor CP Warlow

Thrombolysis for stroke in the UK: room for improvement? Professor Peter Sandercock , Western General Hospital Edinburgh Does reliable diagnosis of TIA require a neurologist? Professor Peter Rothwell, Radcliffe Infirmary, Oxford
THURSDAY 31 MARCH 2005 AT 1345 – 1500 hrs
Knight's move thinking? Mild cognitive impairment in a chess player Sporadic Creutzfeldt-Jakob disease identified only at autopsy: why are cases missed in life? Creutzfeldt Jakob disease (CJD) associated with human dura mater - experience from UK surveillance Non convulsive status epilepticus in Creutzfeldt-Jakob disease - a short report
Magnetization transfer spectroscopy in patients with epilepsy Costs and outcomes of pregabalin versus other new anti-epileptic drugs indicated as add-on therapy in MR-tractography predicts visual field defects following temporal lobe resection The prevalence of structural abnormalities in clinically selected patients with chronic headache and seizure Tolerability of polytherapy with sodium valproate, topiramate and lamotrigine
An audit of the use of laboratory diagnostic tests in herpes simplex virus encephalitis Voltage gated potassium channel antibody associated limbic encephalitis: a case of acute amnesia and The UK multiple sclerosis database: A tool for MS care and research Diagnostic yield of brain biopsy in neurology patients at Atkinson Morley Hospital (AMH), 1993-2002 Neuropathological features of multiple sclerosis (MS) can be seen in a humanized mouse model of EAE A pharmacogenetic screen of 100 interferon regulated genes in relation to (non-) responsiveness to IFN-β Interlukin-4 and interlukin-4 receptor polymorphisms: influence on clinical course of multiple sclerosis Polymorphisms in the interferon-gamma gene modify sex-associated risk for multiple sclerosis

Spinocerebellar ataxia type 17: extension of phenotype with putaminal rim hyperintensity on magnetic Spondyloepiphyseal dysplasia presenting with cervical myelopathy The outcome of referral of patients with functional neurological symptoms or psychiatric disorders for psychological therapy from a general clinic - a pilot study Neuroradiology in a district general hospital Trigeminal neuralgia as a presenting feature of Lhermitte Duclos disease Viral vectors for immunisation against potassium channel Kv1.2 The comprehensive neurological examination in 1897 compared with 2002 - from Hutchison's clinical Fragile-x-associated tremor/ataxia syndrome in a woman unmasked by chemotherapy Email teleneurology to the developing world: the experience of the Swinfen Charitable Trust
Movement Disorders
The role of the acute dopaminergic challenge re-visited New levodopa/carbidopa/entacapone (Stalevo®) provides better quality of life for Parkinson's disease Chorea associated with thyroxine replacement therapy Treatment change in the first 12 months of Parkinson's disease treatment Differentiating drug-induced parkinsonism from Parkinson's disease with FP-CIT SPECT (DaTSCAN): Sydenham's chorea with anti-basal ganglia antibodies, new-onset diabetes mellitus and prominent basal The basal ganglia cholinergic neurochemistry of progressive supranuclear palsy
Tacrolimus induced chronic inflammatory demyelinating polyneuropathy and ischaemic stroke Childhood onset demyelinating neuropathy and cataracts: a potentially treatable disorder A nosological case study of Brown-Vialetto-Van Laere syndrome using neurophysiological and proton magnetic resonance spectroscopy techniques Mycophenolate mofetil for dysimmune neuromuscular diseases: experience in a Muscle sampling in inclusion body myositis The genetic diagnosis of congenital myasthenic syndromes (CMS) A sting in the tale - a unique case of wasp-induced autoimmune neuromyotonia
Acute ischaemic stroke management: numbers not treated Antiplatelet agents for secondary stroke prevention. Has primary care taken on board the RCP guidance? Ascending myelopathy following spinal cord injury is probably due to venous infarction Location-specific volume of early perihaematoma oedema Use of arch aortography for assessment of carotid stenosis prior to stenting or surgery. The Sheffield Plasma D-dimer levels in intracranial venous thrombosis


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