Bedeutung von Epikutantest und Lymphozytentransformationstest für die Diagnostik von Typ IV-Sensibilisierungen. Stellungnahme des Deutschen Berufsverband der Umweltmediziner Significance of the patch test and the lymphocyte transformation test in the diagnostic of type IV-Statement of the German professional association for enviromental medicine Frank Bartram1, Hans-Peter Donate2, K
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Agrodraft.readydesign.netSECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.2. Relevant identified uses of the substance or mixture and uses advised against 1.3. Details of the supplier of the safety data sheet Agropharm LimitedBuckingham Place,Church Road, Penn,High WycombeBucksHP10 8LNTel: +44 (0) 1494 816575Factory: +44 (0)1952 740333Fax: +44 (0) 1494 [email protected] 2.1. Classification of the substance or mixture Physical and Chemical HazardsProduct burns without a flame to give a dense white harmful smoke.
May cause sensitisation by skin contact.
Harmful by inhalation and if swallowed.
Very toxic to aquatic organisms, may cause long-term adverse effects in the Keep away from food, drink and animal feeding stuffs.
Keep away from sources of ignition - No smoking.
When using do not eat, drink or smoke.
This material and its container must be disposed of in a safe way.
Wear suitable protective clothing, gloves and eye/face protection.
Use appropriate containment to avoid environmental contamination.
Do not breathe spray.
Do not breathe smoke/fumes.
SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS The Full Text for all R-Phrases and Hazard Statements are Displayed in Section 16.
General informationRemove affected person from source of contamination. Remove contaminated clothing immediately and dispose of safely.
InhalationRemove victim immediately from source of exposure. Provide fresh air, warmth and rest, preferably in a comfortable upright sitting position. Get medical attention if any discomfort continues.
IngestionRinse mouth thoroughly. DO NOT induce vomiting. Get medical attention immediately.
Skin contactRemove contaminated clothing immediately and wash skin with soap and water. Get medical attention if irritation persists after washing.
Eye contactImmediately flush with plenty of water for up to 15 minutes. Remove any contact lenses and open eyes wide apart. Get medical attention 4.2. Most important symptoms and effects, both acute and delayed 4.3. Indication of any immediate medical attention and special treatment needed This product contains a Pyrethoid, and MUST NOT be confused with organophosphorus compounds.
Extinguishing mediaExtinguish with alcohol-resistant foam, carbon dioxide, dry powder or water fog. Do not use high volume water jet.
5.2. Special hazards arising from the substance or mixture Unusual Fire & Explosion HazardsIn case of fire the evolution of dangerous gases is possible. Contains potassium chlorate which is classified as an oxidising agent. This will assist combustion in a fire situation.
Special Fire Fighting ProceduresAvoid breathing fire vapours. Containers close to fire should be removed or cooled with water. Dike and collect extinguishing water.
Protective equipment for fire-fightersSelf contained breathing apparatus and full protective clothing must be worn in case of fire.
6.1. Personal precautions, protective equipment and emergency procedures Wear protective clothing as described in Section 8 of this safety data sheet.
Do not discharge into drains, water courses or onto the ground. Spillages or uncontrolled discharges into watercourses must be IMMEDIATELY alerted to the Environmental Agency or other appropriate regulatory body.
6.3. Methods and material for containment and cleaning up Avoid contact with skin or inhalation of spillage, dust or vapour. Remove spillage with vacuum cleaner. If not possible, collect spillage with shovel, broom or the like. Collect spillage in containers, seal securely and deliver for disposal according to local regulations. Do not Read and follow manufacturer's recommendations. Avoid inhalation of dust and contact with skin and eyes. Do not eat, drink or smoke when 7.2. Conditions for safe storage, including any incompatibilities Keep separate from food, feedstuffs, fertilisers and other sensitive material. Store in tightly closed original container in a dry and cool place. Keep away from heat, sparks and open flame.
Storage ClassKeep in pesticide store - product is an insecticide of low toxicity. Physically and chemically stable for at least 2 years when stored in the original, unopened containers at ambient temperatures.
Usage DescriptionPesticide smoke generator.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION Ingredient CommentsWhen using this product, refer to the label for details. Should it be necessary to enter the treated area whilst smoke remains in the atmosphere, respiratory protective equipment and eye protection must be used (see HSE Guidance Booklet (HS)G53 'Respiratory Protective Equipment - A Practical Guide for Users') Respiratory equipmentNo specific recommendation made, but respiratory protection may still be required under exceptional circumstances when excessive air contamination exists.
Hand protectionFor prolonged or repeated skin contact use suitable protective gloves.
Eye protectionWear approved chemical safety goggles where eye exposure is reasonably probable.
Hygiene measuresWash contaminated clothing before reuse. Wash hands at the end of each work shift and before eating, smoking and using the toilet.
Skin protectionWear apron or protective clothing in case of contact.
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1. Information on basic physical and chemical properties Stable under normal temperature conditions and recommended use.
Avoid exposure to high temperatures or direct sunlight.
Materials To AvoidFlammable/combustible material.
Thermal decomposition or combustion may liberate carbon oxides and other toxic gases or vapours.
11.1. Information on toxicological effects Toxicological informationOral LD50 (rat) 1479 mg/kg Permethrin, Oral LD50 (rat) 1260 mg/kg Potassium Chlorate.
InhalationSmoke may cause upper airway irritation.
IngestionBurning in mouth, vommiting, nausea, tremors and convulsions may occur.
Skin contactMay cause skin irritation/eczema. May cause sensitisation by skin contact.
Eye contactMay cause temporary eye irritation.
Route of entryInhalation. Skin and/or eye contact. Ingestion.
Acute Fish ToxicityVery toxic to aquatic organisms.
LC 50, 96 Hrs, Fish mg/l DegradabilityThe product is not readily biodegradable.
General informationThis material and its container must be disposed of in a safe way.
ENVIROMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (PERMETHRIN MIXTURE) Class 9: Miscellaneous dangerous substances and articles.
90 Environmentally hazardous substance; miscellaneous dangerous substances.
14.7. Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture Uk Regulatory ReferencesThis product is approved under the Control of Pesticides Regulations 1986. HSE No. 7187.
General informationThis product is approved under the Control of Pesticides Regulations 1986 (as amended). The information contained in this Safety Data Sheet is believed to be true and correct, as of the issue date. The accuracy and completeness of this information and any recommendations, or suggestions are made without warranty or guarantee. Since the conditions of use are beyond the control of our company, it is the responsibility of the user to determine the conditions of safe use for this product.
Revision Date Explosive when mixed with combustible material.
Harmful by inhalation and if swallowed.
May cause sensitisation by skin contact.
Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
May cause an allergic skin reaction.
May cause fire or explosion; strong oxidiser.
Toxic to aquatic life with long lasting effects.
Very toxic to aquatic life with long lasting effects.
This information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process. Such information is, to the best of the company's knowledge and belief, accurate and reliable as of the date indicated. However, no warranty guarantee or representation is made to its accuracy, reliability or completeness. It is the user's responsibility to satisfy himself as to the suitability of such information for his own particular use.
KOPFSCHMERZ-NEWS Aktuelle Literatur zur Pathophysiologie und Herausgeber: Prof. Dr. Hans-Christoph Diener, Universitätsklinik für Neurologie, Hufelandstr. 55, 45122 Essen, im Auftrag der Deutschen Migräne- und Kopfschmerzgesellschaft Autoren dieser Ausgabe: • Prof. Dr. H.C. Diener, Neurologische Universitätsklinik, Hufelandstr. 55, 45122 Essen • PD Dr. Z. Katsarava, N