Bardzo tanie apteki z dostawą w całej Polsce kupic viagra i ogromny wybór pigułek.

Curriculum vitae

PUBLICATIONS
Enzymic Synthesis of L-Ascorbic Acid in Different Animal Species. Arch. Biochem. Biophys. 69, 458-467 (1957)
The Enzyme Conversion of D-Glucuronate to L-Ascorbate and L-Xylulose in Animal Tissues. Biochem. Biophys. Acta 27, 221-222 (1958)
Metabolic Alkalosis, A Specific Effect of Adrenocortical Hormones. Am. J. Physiol. 196, 135-140 (1959)
Biochem. Biophys. Acta. 47, 298-306 (1961)
J. Clin. Invest. 40, 1290-1296 (1961)
The Removal of Bilirubin by Albumin Binding During Peritoneal Dialysis. New Eng. J. Med. 267, 279-282 (1962)
Site of Reabsorption of Citrate and Calcium in the Renal Tubule of the Dog Am. J. Physiol. 205, 697-701 (1963)
Polysaccharide Antigens of Candida Cell Wall J. Immunology 92, 491-499 (1964)
O-Phosphorylethanolamine: A Component of Lipopolysaccharide in Certain Gram-Negative Bacteria Biochemistry 3, 1571-1574 (1964)
Biosynthesis of Fucosyllactose and Other Oligosaccharides Found in Milk J. Biol. Chem. 240, 975-981 (1965)
GDP-L Fucose: Lactose Fucosyltransferase from Mammary Gland Methods in Enzymology VIII, Complex Carbohydrates. Neufeld, E.F. and Ginsburg, V. (Eds.), Academic Press, NY 351-353 (1965). Studies of Blood Group Substances I. Caprine Precipitating Antisera to Human Lea and Leb Blood Group Substances J. Immunology 97, 867-875 (1966).
Enzymatic Incorporation of Fucose in Blood Group H Substance Biochem. Biophys. Res. Commun. 25, 542-548 (1966)
Structural Basis for Inhibition of Protein Biosynthesis by Emetine and Cycloheximide Based on an Analogy Between Ipecac Alkaloids and Glutarmide Antibiotics Proc. Natl. Acad. Sci. USA 56, 1867-1874 (1966)
Studies of Blood Group Substances II. Hemagglutinating Properties of Caprine Antisera to Human Lea and Leb Blood Group Substances Marcus, D.M., Bastani, A.M., Rosenfield, R.E., and Grollman, A.P. Transfusion 7, 277-280 (1967)
Metabolic Pathways Leading to the Biosynthesis of Blood Group Substances Hartford Foundation Symposium on Blood Groups. Kuhns, W.J. (Ed.) J. Biol. Chem. 242, 3326-3333 (1967)
Structural Basis for the Inhibition of Protein Biosynthesis: Mode of Action of Tubulosine Science 157, 84-85 (1967)
Cycloheximide Resistance in Yeast: A Property of the 60s Ribosomal Subunit Biochem. Biophys. Res. Commun. 29, 696-704 (1967)
Effects of Emetine on Protein and Nucleic Acid Biosynthesis in HeLa Cells J. Biol. Chem. 243, 4089-4094 (1968)
Inhibition of the Attachment of Messenger Ribonucleic Acid to Ribosomes Proc. Natl. Acad. Sci. USA 61, 719-725 (1968)
A Proposed Mechanism for the Design of Novel Antiviral Agents Antimicrobial Agents and Chemotherapy—1968, 3640 (1969) Interactions of Small Molecules with Nucleic Acids. I. Mode of Action of Anthramycin. Antimicrobial Agents and Chemotherapy—1968, 21-24 (1969) Rational Design of Chemotherapeutic Agents Annual Reports in Medicinal Chemistry—1968, Cain, C.K. (Ed.), The Ohio State Medical Journal 66, 257-259 (1970)
A fucosyltransferase Found in Human Milk: The Product of the Lewis Blood Group Gene. Biochemistry 9, 1123-1128 (1970)
Inhibition of Protein Biosynthesis: Its Significance in Drug Design Molecular Pharmacology Vol. II, Drug Design. Ariens, E.F. (Ed.) Molecular Pharmacology Vol. II, Drug Design. Ariens, E.F. (Ed.) Aurintricarboxylic Acid: Inhibitor of Protein Synthesis Proc. Natl. Acad. Sci. USA 68, 97-101 (1971)
Chemosterilant Action of Anthramycin: A Proposed Mechanism Horwitz, S.B., Chang, S.C., Grollman, A.P., and Borkovec, A.B. Science 174, 159-161 (1971)
Studies on Camptothecin I. Effects on Nucleic Acid and Protein Synthesis Horwitz, S.B., Chang, C., and Grollman, A.P. Molecular Pharmacology 7, 632-644 (1971)
J. Med. Chem. 14, 885-887 (1971)
Effect of Aurintricarboxylic Acid on Ribosomes and the Synthesis of Globin in Rabbit Reticulocytes Molecular Pharmacology 8, 111-127 (1972)
Horwitz, S.B., Chang, C., and Grollman, A.P. Antimicrobial Agents and Chemotherapy 2, 395-401 (1972)
Mode of Action of Tylocrebine: Effects of Protein and Nucleic Acid Synthesis Molecular Pharmacology 8, 538-550 (1972)
13C-Enriched Methyl-D-Glucopyranisode to Concanavalin A as Studied Brewer, C.F., Sternlicht, H., Marcus, D.M., and Grollman, A.P. Proc. Natl. Acad. Sci. USA 70, 1007-1011 (1973)
Binding of Orientations of α and β Methyl-D-Gluopyranoside to Concanavail A as Studied by 13-Carbon Magnetic Resonance Brewer, C.F. Marcus, D.M., Sternlicht, H., and Grollman, A.P. Ann. NY Acad. Sci. 222, 978-988 (1973)
Interactions of Saccharides with Concanavalin A. II. Mechanism of Binding of Alpha and Beta-Methyl-D-Clucopyranoside to Concanavalin A as Determined by Carbon Magnetic Resonance. Biochemistry 12, 4448-4457 (1973)
Inhibitors of Protein Synthesis in Eukaryotes: Tools in Cell Research Federation Proceedings 32, 1673-1678 (1973)
Inhibitors of Protein Synthesis: A Mechanism of Amebicide Action of Emetine and Other Structurally-Related Compounds J. Protozool. 20, 160-163 (1973)
Pyrocatechol Violet: An Inhibitor of Initiation of Protein Synthesis Biochem. Biophys. Res. Commun. 53, 1049-1059 (1973)
Resonance Studies of Carbohydrate Interactions with Brewer, C.F., Sternlicht, H ., Marcus, D.M., and Grollman, A.P. Biology and Medicine, May 9-11, 1973 at Argonne, Illinois, sponsored by the United States Atomic Energy Commission Interaction of Saccharides with Concanavalin A. III.Relation between Calcium Ions and the Binding of Saccharides to Concanavalin A. Brewer, C.F., Sternlicht, H., Marcus, D.M., and Grollman, A.P. J. Biol. Chem. 259, 4614-4616 (1974)
(9-(2’-Carboxyphenyl)-3,4,5,6-tetrahydroxyxanthene), a New Inhibitor of Escherichia coli Ribonucleic Acid Polymerase Biochemistry 13, 1331-1337 (1974)
Bleomycin, an Inhibitor of Vaccinia Virus Replication Virology 60, 455-465 (1974)
Molecular Pharmacology of Plant Lectins: Studies on Ricin and Concanavalin A Cancer Chemotherapy Reports 58, 491-501 (1974)
Structure Activity Relationships of Adrenergic Compounds on the Adenylate Cyclase of Frog Erythrocytes Grunfield, C., Grollman, A.P. and Rosen, O.M. Molecular Pharmacology 10, 605-614 (1974)
Antibiotics: Mode of Action, Vol. III, 420-435 (1975) Triphenylmethane Dyes as Inhibitors of Reverse Transcriptase, RNA Polymerase, and Protein Synthesis: Structure Activity Relationships Liao, L.L., Horwitz, S.B., Steward, D., Martin, J., Huang, M.T. and Grollman, A.P. J. Med. Chem. 18, 117-120 (1975)
Proton Magnetic Resonance Studies of Carbonic Anhdyrase III. Binding of Sulfonamides Biochemistry 14, 689-693 (1975)
Effect of ATP and other Nucleotides on the Bleomycin-Induced Degradation of Vaccinia Virus DNA Virology 69, 453-463 (1976)
Mechanism of Action of the 12,13-Epoxytrichothecene, Anguidine, an Inhibitor of Protein Synthesis Biochemica et Biophysica Acta 454, 273-284 (1976)
Mechanism of the Antiviral Action of Bleomycin Ann. NY Acad. Sci. 284, 367-374 (1977)
Bleomycin-induced Interactions: Fluorescence and Proton Magnetic Resonance Studies Biochemistry 16, 3641-3647 (1977)
Nucleotide Specificity in DNA Scission by Neocarzinostatin Proc. Natl. Acad. Sci. USA 75, 5983-5987 (1978)
Takeshita, M., Grollman, A.P., Ohtsubo, E., and Ohtsubo, H. Proc. Natl. Acad. Sci. USA 75, 5983-5987 (1978)
A Molecular Basis for the Interaction of Bleomycin with DNA Bleomycin, Chemical, Biochemical and Biological Aspects Hecht, S. (Ed.), Springer Verlag, NY 207-221 (1979) Advances in Enzyme Regulation, Weber, G. (Ed.) 18, 67-68 (1980)
Scission of DNA: Mechanisms of Deoxyribose Giloni, L., Takeshita, M., Johnson, F., Iden, C., and Grollman, A.P. J. Biol. Chem. 256, 8606-8615 (1981)
Interaction of Bleomycin with Deoxyribodinucleotides: An NMR Study Biochemistry 20, 7589-7598 (1981)
Strand-Scission of DNA by Neocarzinostatin, Auromomycin, and Bleomycin: Studies on Base Release and Sequence Specificity Takeshita, M., Kappen, L., Grollman, A.P., and Goldberg, I. Biochemistry 20, 7599-7606 (1981)
Biomolecular Stereodynamics, Sarma, R.H. (Ed.), Adenine Press 2, 401-
408 (1981)
Synthesis and Biological Activities of a New Class of Cytotoxic Agents: (N-(3-Oxoprop-1-enyl)-Substituted Pyrimidines and Purines Johnson, F., Pillai, K.M.R., Grollman, A.P., Tseng, L ., and Takeshita, M. J. Med. Chem. 27, 954 (1984)
Origin and Cytotoxic Base Properties of Propenals Derived from DNA Cancer Res. 45, 1127-1131 (1985)
Cancer Chemotherapy Experimental and Clinical Progress Martinus Nijhoff Publishers, Boston (1985) Cytotoxic Base Propenals and the Action of Bleomycin Grollman, A.P., Johnson, F., Pillai, K.M.R., and Takeshita, M. Molecular Basis of Cancer Bart B: Macromolecular Recognition, Chemotherapy, and Immunology, Alan R. Liss, Inc., 235-242 (1985). Carcinogen Induced Insertion Mutations in E. coli Takeshita, M., Van der Keyl, H., and Grollman, A.P. Molecular Basis of Cancer, Part A: Macromolecular Structure, Carcinogenesis, and Oncogenes, Alan R. Liss, Inc., 389-399 (1985). Steptonigrin I. Structure-Activity Relationships Among Simple Bicyclic Analogues. Rate Dependence of DNA Degradation on Quinone Reduction Potential Shaikh, I.A., Johnson, F., and Grollman, A.P. J. Med. Chem. 29, 1329-1340 (1986)
Containing Synthetic Abasic Sites: Model Substrates for Takeshita, M., Chang, C.-N., Johnson, F., Will, S.G., and Grollman, A.P. J. Biol. Chem. 262, 10171-10179 (1987)
NMR Studies of Abasic Sites in DNA Duplexes. Deoxyadenosine Stacks into the Helix Opposite the Cyclic Analog of 2-Deoxyribose Kalnick, M., Chang, C.-N., Grollman, A.P., and Patel, D.J. Biochemistry 27, 924-931 (1988)
Targeted Mutations Induced by a Single Acetylaminofluorene DNA Adduct in Mammalian Cells and Bacteria Moriya, M., Takeshita, M., Johnson, F., Peden, K., Will, S., and Grollman, A.P. Proc. Natl. Acad. Sci. USA 85, 1586-1589 (1988)
Base Propenals and the Toxicity of Bleomycin. Organ Directed Toxocities of Anticancer Drugs. Hacker, M.P., Lazo, J.S., and Tritton, T.R. (Eds.), Martinus Nijhoff Publishers, 79-90 (1988) Experimental System for the Study of Site-Specific Mutagenesis in Mammalian Cells and Bacteria Moriya, M., Takeshita, M., Peden, K., and Grollman, A.P. DNA Replication and Mutagenesis. Moses, R.E. and Summers, W.C. Mechanism of DNA Cleavage and Substrate Recognition by a Bovine Apurinic Endonuclease Sanderson, J.S., Chang, C.-N., Grollman, A.P., and Henner, W.D. Biochemistry 28, 3894-3901 (1989)
NMR Studies of Abasic Sites in DNA Duplexes: Deoxyadenosine Stacks into the Helix Opposite Acyclic Lesions Kalnick, M.W., Chang, C.-N., Johnson, F., Grollman, A.P., and Patel, D.J. Biochemistry 28, 3373-3383 (1989)
Influence of Abasic and Anucleosidic Sites on the Stability, Conformation, and Melting Behavior of a DNA Duplex: Correlations of Thermodynamic and Structural Data Vesnaver, G., Chang, C.-N., Eisenberg, M.E., Grollman, A.P., and Breslauer, K.J. Proc. Natl. Acad. Sci. USA 86, 3614-3618 (1989)
NMR Studies of Exocyclic 1,N2-Propanodeoxyguanosine Adducts (X) Opposite Purines in DNA Duplexes: Protonated X(syn)•A(anti) Pairing (Acidic pH) and X(syn)•G(anti) Pairing (Neutral pH) at the Lesion Site Kouchakdjian, M., Marinelli, E., Gao, X., Johnson, F., Grollman, A.P., and Patel, D.J. Biochemistry 28, 5647-5657 (1989)
In: Fifth International Conference on Environmental Mutagens, Mutation and the Environment, Part A, NMR Studies of an Exocyclic 1,N2-Propanodeoxyguanosine Adduct (X) Located Opposite Deoxyadenosine (A) in DNA Duplexes at Basic pH: Simultaneous Partial Intercalation of X and A Between Stacked Bases Kouchakdjian, M., Eisenberg, M., Live, D., Marinelli, E., Grollman, A.P.,
and Patel, D.J.
Biochemistry 29, 4456-4465 (1990).
Insertion of Specific Bases During DNA Synthesis past the Oxidation-damaged Base 8-oxodG Nature 349, 431-434 (1991).
NMR Structural studies of the Ionizing Radiation Adduct 8-Oxodeoxyguanosine (8-oxodG) Opposite Deoxyadenosine in a DNA Duplex. 8-OxodG(syn):dA(anti) Alignment at Lesion Site Kouchakdjian, M., Bodepudi, V., Shibutani, S., Eisenberg, M., Johnson, F., Grollman, A.P., and Patel, D.J. Biochemistry 30, 1403-1412 (1991).
an Exocyclic Adduct Positioned Opposite an Abasic Site in Kouchakdjian, M., Eisenberg, M., Johnson, F., Grollman, A.P., and Patel,
D.J.
Biochemistry 30, 3262-3270 (1991).
Isolation and Characterization of Oligodeoxynucleotides Containing dG-N2-AAF and Oxidation Products of dG-C8-AF Shibutani, S., Gentles, R., Johnson, F., and Grollman, A.P. Carcinogenesis 12, 813-818 (1991).
Site-specific Mutagenesis using a Gapped Duplex Vector: A Study of In Vivo Translesion Synthesis past 8-Oxodeoxyguanine. Moriya, M., Ou, C., Bodepudi, V., Johnson, F., Takeshita, M., and Grollman, A.P. Mutation Res. 254, 281-288 (1991).
8-Oxoguanine (8-Hydroxyguanine) DNA Glycosylase and its Substrate Specificity Tchou, J., Kasai, H., Shibutani, S., Chung, M.H., Laval, J., Grollman, A.P., and Nishimura, S. Proc. Natl. Acad. Sci. USA 88, 4690-4694 (1991).
Japan J. Cancer Res. 82, Elsevier Science Publishers (1991).
Inhibition of Cellular Thymidylate Synthesis by Cytotoxic Propenal Derivatives of Pyrimidine Bases and Deoxynucleosides Kalman, T.I., Marinelli, E.R., Xu, B., Benugopala Reddy, A.R., Johnson,
F., and Grollman, A.P.
Biochemical Pharmacology 42, 432-437 (1991).
Structural Basis for the Mutagenic Specificity of 8-Oxoguanine-DNA. In: Proceedings of the Seventh Conversation in Biomolecular Stereodynamics. Sarma, R. (Ed.), Adenine Press (1992). MutY and MutM Combine to Prevent Mutations by an Oxidatively Michaels, M.L., Cruz, C., Grollman, A.P., and Miller, J.H. Proc. Natl. Acad. Sci. USA 89, 7022-7025 (1992).
A Repair System for 8-Oxo-7,8-dihydrodeoxyguanine (8-Hydroxyguanine) Michaels, M.L., Tchou, J., Grollman, A.P., and Miller, J.H. Biochemistry 31, 10964-10968 (1992).
Influence of an Exocyclic Guanine Adduct on the Thermal Stability, Conformation, and Melting Thermodynamics of a DNA Duplex. Biochemistry 31, 12096-12102 (1992).
Synthesis on DNA Templates Containing 8-Oxo-7,8- Shibutani, S., Bodepudi, V., Johnson, F., and Grollman, A.P. Biochemistry 32, 4615-4621 (1993).
Repair of DNA Containing the Oxidatively-Damaged Base, 8-Oxoguanine Mutation Res. 299, 277-287 (1993).
on DNA Template Containing a Single Stereoisomer of dG-(+)- or dG0(-)-anti-BPDE (7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene). Shibutani, S., Margulis, L.A., Geacintov, N.E., and Grollman, A.P. Biochemistry 32, 7531-7541 (1993).
Mutagenesis by 8-Oxoguanine: An Enemy Within Trends in Genetics 9, 246-249 (1993).
On the Mechanism of Frameshift (Deletion) Mutagenesis In Vitro J. Biol. Chem. 268, 11703-11710 (1993).
Mutations of the MutY Gene of Escherichia coli Enhance the Frequency of Targeted G:C→T:A Transversions Induced by a Single 8-Oxoguanine Residue in Single-Stranded DNA. Molecular Gen. Genet. 239, 72-76 (1993).
Mutagenic Specificity of Chemical Carcinogens as Determined by Studies with Single DNA Adducts DNA Adducts: Identification and Biological Significance. Hemminki, K., Dipple, A., Shuker, D., Kadlubar, F.F., Segerback, D. and Bartsch, H. (Eds.), IARC Scientific Publications No. 125, Lyon, France, (1993). Function of the Zinc Finger Domain in Escherichia coli Fpg Protein Tchou, J., Michaels, M.L., Miller, J.H., and Grollman, A.P. J. Biol. Chem. 268, 26738-26744 (1993).
100. Nucleotide Misincorporation on DNA Templates Containing N-(deoxyguanosin- N2-yl)-2-acetylaminofluorene (dG-N2-AAF) Chem. Res. Toxicol. 6, 819-824 (1993).
of Formation, and Repair of Oxidative 8-Hydroxyguanine Kasai, H., Chung, M.H., Yamamoto, F., Ohtsuka, E., Laval, J., Grollman, A.P., and Nishimura, S. Basic Life Sciences 61, 257-262 (1993).
102. Substrate Specificity of Fpg Protein: Recognition and Cleavage of Oxidatively Tchou, J., Bodepudi, V., Shibutani, S., Antoshechkin, I., Miller, J., Grollman, A.P., and Johnson, F. J. Biol. Chem. 269, 15318-15324 (1994)
103. Recognition and Repair of 8-Oxoguanine and Formamidopyrimidine Lesions in Annals of New York Academy of Sciences 726. Wallace, S.S., Van
Houten, B., and Kow, Y.W. (Eds.), 208-214 (1994). 104. Miscoding During DNA Syntheisis on Damaged DNA Templates Catalyzed by Cancer Letters 83, 315-322 (1994).
105. Mutagenic Potency of Exocyclic DNA Adducts: Marked Differences Between Escherichia coli and Simian Kidney Cells Moriya, M., Zhang, W., Johnson, F., and Grollman, A.P. Proc. Natl. Acad. Sci. USA 91, 11899-11903 (1994).
106. Miscoding by the Exocyclic DNA Adducts: 3,N4-etheno-2’-deoxycytidine, 3,N4- ethano-2’-deoxycytidine, and 3-(2-hydroxyethyl)-2’-deoxyuridine Zhang, W., Johnson, F., Grollman, A.P., and Shibutani, S. Chem. Res. Toxicol. 8, 157-163 (1995).
107. 8-Oxoguanine in DNA: Its Mutagenic Properties and Repair Grollman, Environ. Mut. Res. Commun. 16, 239-243 (1995).
108. Incision Activity of Human Apurinic Endonuclease (a.p.e) at Abasic Site Analogs J. Biol. Chem. 270, 16002-16007 (1995).
109. The Catalytic Mechanism of Fpg Protein: Evidence for a Schiff Base Intermediate and Amino-Terminus Localization of the Catalytic Site J. Biol. Chem. 270, 11671-11677 (1995).
110. Miscoding and Mutagenic Properties of 8-Oxoguanine and Abasic Sites: Radiation Damage to DNA: Structure/Function Relationships of Early Times. Fuciarelli, A.F. and Zimbrick, J.D. (Eds.), Batelle Press, Columbus, Ohio, 293-304 (1995). 111. Influence of the Oxidatively Damaged Adduct 8-Oxodeoxyguanosine on the Conformation, Energetics, and Thermodynamic Stability of a DNA Duplex. Biochemistry 34, 16148-16160 (1995).
112. Mutagenicity of a Unique 8-Oxoguanine in a Human Ha-ras Sequence in LePage, F., Margot, A., Grollman, A.P., Sarasin, A., and Gentil, A. Carcinogenesis 16, 2779-2784 (1995).
8-Oxo-7,8-Dihydro-6-O-Methyl-2’-deoxyguanosine and its Use as a Probe to Study DNA-Base Excision by MutY Enzyme Varaprasad, C.V., Bulychev, N., Grollman, A.P., and Johnson, F. Tetrahedron Letters 37, 9-12 (1996).
Translesional Synthesis Past Benzo[a]pyrene Diol Epoxide-2- Deoxyguanosine DNA Adducts: Marked Effects of Host Cell Sequence Context and Chirality Moriya, M., Spiegel, S., Fernandes, A., Amin, S., Liu, T.-M., Geacintov, N.E., and Grollman, A.P. Biochemistry 35, 16646-16641 (1996).
115. Analysis and Prediction of Protein Binding on DNA: Pattern Recognition of Campbell, G., Deng, Y., Glimm, J., Yu, Q., Eisenberg, M., and Grollman, A.P. J. Computational Chemistry 17, 1712-1725 (1996).
116. Substrate Specificity of E. coli MutY Protein Bulychev, N.V., Varaprasad, C.V., Dorman, G., Miller, J.H., Eisenberg, M.,
Grollman, A.P., and Johnson, F.
Biochemistry 35, 13147-13156 (1996).
117. The Impact of a Bistrand Abasic Lesion on DNA Duplex Properties Gelfand, C.A., Plum, G.E., Grollman, A.P., Johnson, F., and Breslauer,
K.J.
Biopolymers 38, 439-445 (1996).
118. Solution Structure of an Oligodeoxynucleotide Duplex Containing the Exocyclic Lesion 3,N4-ethenodeoxycytosine Opposite Deoxyadenine, Determined by NMR Spectroscopy and Restrained Molecular Dynamics Korobka, A., Cullinan, D., Cosman, M., Grollman, Patel, D.J., Eisenberg,
M., and de los Santos, C.
Biochemistry 35, 13310-13318 (1996).
119. NMR Solution Structure of an Oligodeoxynucleotide Duplex Containing the Exocyclic Lesion 3,N4-ethenodeoxycytosine Opposite Thymine: Comparison with the Duplex Containing Deoxyadenosine Opposite the Adduct Cullinan, D., Korobka, A., Grollman, A.P., Patel, D.J., Eisenberg, M., and de los Santos, C. Biochemistry 35, 13319-13327 (1996).
120. Deletions and Insertions of p53 Tumor Suppressor Gene in Human Cancers: Confirmation of the DNA Polymerase Slippage/Misalignment Model Cancer Res. 56, 2130-2136 (1996).
121. 8-Oxoguanine and Bistrand Abasic Sites in DNA: Mutagenic Potential and Radiation Research 1895-1995. Congress Proceedings Vol. 2 Hagen, U., Hrder, D., Jung, H., and Streffer, C. (Eds)., 316-319 (1996) 122. Miscoding Properties of 3,N4-Etheno-2’-deoxycytidine in Reactions Catalyzed by Shibutani, S., Suzuki, N., Matsumoto, Y., and Grollman, A.P. Biochemistry 35, 14992-14998 (1996).
the Ionizing Radiation Adduct 7,8-Dihydro-8-oxoadenine (Aoxo) Positioned Opposite Thymine in a DNA Duplex Chen, H., Johnson, F., Grollman, A.P., and Patel, D.J. Magnetic Resonance in Chemistry 34, S23-S32 (1996).
124. Kinetics of Excision of Purine Lesions from DNA by Fpg Protein Karakaya, A., Jaruga, P., Bohr, V.A., Grollman, A.P., and Dizdaroglu, M. Nucleic Acids Research 25, 474-479 (1997).
125. Solution Structure of a DNA Duplex Containing the Exocyclic Lesion 3,N4- Etheno-2’-deoxycytidine Opposite 2’-Deoxyguanosine Cullinan, D., Johnson, F., Grollman, A.P., Eisenberg, M., and de los Santos, C. Biochemistry 36, 11933-11943 (1997).
126. NH2-Terminal Proline Acts as a Nucleophile in the Glycosylase/Ap-Lyase Reaction Catalyzed by Escherichia coli Formamidopyrimidine-DNA Glycosylase (Fpg) Protein Zharkov, D., Rieger, R.A., Iden, C.R., and Grollman, A.P. J. Biol. Chem. 272, 5335-5341 (1997).
on DNA Templates Containing a Single Abasic Site: A J. Biol. Chem. 272, 13916-13922 (1997).
128. Molecular Mechanisms of Mutagenesis by Aromatic Amines and Amides Mutation Res. 376, 71-78 (1997).
129. Cloning and Characterization of a Mammalian 8-Oxoguanine DNA Glycosylase Rosenquist, Proc. Natl. Acad. Sci. USA 94, 7429-7434 (1997).
130. Kinetics of DNA Polymerase I (Klenow Fragment exo-) Activity on Damaged DNA Templates: Effect of Proximal and Distal Template Damage on DNA Synthesis Biochemistry 36, 15336-15342 (1997).
131. Extrachromosomal Unequal Homologous Recombination and Gene Conversion in Simian Kidney Cells: Effects of UV Damage Gening, L., Takeshita, M., Levine, R.L., Peden, K.W., and Grollman, A.P. Mutation Res. 407, 11-24 (1998).
132. Mutagenic Potential of Stereoisomeric Bay Region (+)- and (B)-cis-anti- Benzo[a]pyrene Diol Epoxide-N2-2’-Deoxyguanosine Adducts in Escherichia coli and Simian Kidney Cells Fernandes, A., Liu, T., Amin, S., Geacintov, N.E., Grollman, A.P., and Moriya, M. Biochemistry 37, 10164-10172 (1998).
133. Mutagenic Specificity of Acetylaminofluorene-derived DNA Adducts in Biochemistry 37, 12034-12041 (1998).
134. MutY DNA Glycosylase: Base Release and Intermediate Complex Formation Biochemistry 37, 12384-12394 (1998).
135. Solution Structure of Duplex DNA Containing an Extrahelical Abasic Site Analog Determined by NMR Spectroscopy and Molecular Dynamics Lin, Z., Hung, K.-N., Grollman, A.P., and de los Santos, C. Nucleic Acids Research 26, 2385-2391 (1998).
136. The Impact of an Exocyclic Cytosine Adduct on DNA Duplex Properties: Significant Thermodynamic Consequences Despite Modest Lesion-Induced Structural Alterations Gelfand, C.A., Plum, G.E., Grollman, A.P., Johnson, F., and Breslauer, K.J. Biochemistry 37, 12507-12512 (1998).
137. Thermodynamic Consequences of an Abasic Lesion in Duplex DNA are Strongly Gelfand, C.A., Plum, G.E., Grollman, A.P., Johnson, F., and Breslauer, K.J. Biochemistry 37, 7321-7327 (1998).
138. Site-specific Mutagenesis of the N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine DNA Adduct in Mammalian Cells Shibutani, S., Fernandes, A., Suzuki, N., Zhou, L., Johnson, F., and Grollman, A.P. Z. Lebensm Unters Forsch A 207, 459-463 (1998).
139. Endogenous DNA Damage, Mutagenesis, and Aging Grollman, A.P., Moriya, M., Shibutani, S., and Takeshita, M. In: Molecular Biology of Aging, Alfred Benzon Symposium 44. Bohr, V.A., Clark, B.F.C., Stevnsner, T. (Eds.), Munksgaard, Copenhagen, 191-201 (1999). 140. Mutagenic Properties of the 8-Amino-2’-deoxyguanosine DNA Adduct in Tan, X., Suzuki, N., Johnson, F., Grollman, A.P., and Shibutani, S. Nucleic Acids Research 27, 2310-2314 (1999).
Binding to DNA in the Presence of Water-Mediated Deng, Y., Glimm, J., Wang, Y., Korobka, A., Eisenberg, M., and Grollman, A.P. J. Mol. Model. 5, 125-133 (1999).
Detected in Endometrium Obtained from Patients Shibutani, S., Suzuki, N., Terashima, I., Sugarman, S.M., Grollman, A.P., and Pearl, M.L. Chem. Res. Toxicol. 12, 646-653 (1999).
143. Recognition and Excision of Bases from Oxidatively Damaged DNA by Fpg, Advances in DNA Damage and Repair. Oxygen Radical Effects, Cellular Protection, and Biological Consequences. Dizdaroglu, M. and Karakaya, A.E. (Eds.), Plenum Publishers, NY, 135-148 (1999). 144. 3,N4-Ethano-2’-deoxycytidine: Chemistry of Incorporation into Oligomeric DNA Bonala, R.R., Rieger, R.A., Shibutani, S., Grollman, A.P., Iden, C.R., and
Johnson, F.
Nucleic Acids Res. 27, 4725-4733 (1999).
145. Mutagenesis of the N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine DNA Adduct in Mammalian Cells Shibutani, S., Fernandes, A., Suzuki, N., Zhou, L., Johnson, F., and
Grollman, A.P.
J. Biol. Chem. 274, 27433-27438 (1999).
146. Comparison of the Mutagenic Properties of 8-Oxo-7,8-dihydro-2’- deoxyadenosine and 8-Oxo-7,8-dihydro-2’-deoxyguanosine DNA Lesions in Mammalian Cells. Suzuki, N., Grollman, A.P., and Shibutani, S. Carcinogenesis 20, 2287-2292 (1999).
147. Cellular Response to Exocyclic DNA Adducts Moriya, M., Pandya, G.A., Johnson, F., and Grollman, A.P. Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis. Singer, B. & Bartsch, H. (Eds.), IARC Scientific Publication (Lyon) 150,
263-270 (1999).
148. 8-OxoGTP Incorporation by DNA Polymerase β is Modified by Active-Site Miller, H., Prasad, R., Wilson, S.H., Johnson, F., and Grollman, A.P. Biochemistry 39, 1029-1033 (2000).
149. Immunolocalization of 8-Oxoguanine in Nutrient-Deprived Mammalian Tissue J. Histotechnology 23, 37-44 (2000).
150. Characterization of a Cross-Linked DNA-Endonuclease VIII Repair Complex by Electrospray Ionization Mass Spectrometry Rieger, R.A., McTigue, M.M., Kycia, J.H., Gerchman, S.E., Grollman, A.P., and Iden, C.R. J. Am. Soc. Mass Spectrometry 11, 505-515 (2000).
of Tamoxifen-DNA Adducts in the Endometrium of Women Treated Shibutani, S., Ravindernath, A., Suzuki, N., Terashima, I., Sugarman, S.M., Grollman, A.P., and Pearl, M.L. Carcinogenesis 21, 1461-1467 (2000).
152. Substrate Specificity and Reaction Mechanism of Murine 8-Oxoguanine-DNA Zharkov, D.O., Rosenquist, T.A., Gerchman, S.E., and Grollman, A.P. J. Biol. Chem. 275, 28607-28617 (2000).
153. Mutagenesis Induced by a Single 1,N6-Ethanodeoxyadenosine Adduct in Human Levine, R.L., Yang, I.Y., Hossain, M., Pandya, G.A., Grollman, A.P., and Moriya, M. Cancer Res. 60, 4098-4104 (2000).
154. A Role for Lysine 142 in the Excision of Adenine from A:G Mispairs by MutY DNA Zharkov, D.O., Gilboa, R., Yagil, I., Kycia, J.H., Gerchman, S.E., Shoham, G., and Grollman, A.P. Biochemistry 39, 14768-14778 (2000).
155. Escherichia coli Response to a Single DNA Adduct Pandya, G.A., Yang, I-Y., Grollman, A.P., and Moriya, M. J. Bacteriology 182, 6598-6604 (2000).
156. Responses to the Major Acrolein-Derived Deoxyguanosine Adduct in Escherichia Yang, I-Y, Hossain, M., Miller, H., Khullar, S., Johnson, F., Grollman, A.P., and Moriya, M. J. Biol. Chem. 276, 9071-9076 (2001).
157. Influence of Flanking Sequence Context on the Mutagenicity of Acetylaminofluorene-Derived DNA Adducts in Mammalian Cells Shibutani, S., Suzuki, N., Tan, X., Johnson, F., and Grollman, A.P. Biochemistry 40, 3717-3722 (2001).
158. Translesion DNA Synthesis Catalyzed by Human Pol η and Pol κ across 1,N6- Levine, R.L., Miller, H., Grollman, A.P., Ohashi, E., Ohmori, H., Masutani, C., Hanoaka, F., and Moriya, M. J. Biol. Chem. 276, 18717-18721 (2001)
159. Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by Human DNA polymerase κ and Escherichia coli DNA polymerase IV. Suzuki, N., Ohashi, E., Yahashi, K., Ohmori, H., Grollman, A.P. and Shibutani, S. Biochemistry 40, 15176-15183 (2001).
160. Alternative medicine: the importance of evidence in medicine and in medical education. Is there wheat among the chaff? Acad Med. 76, 221-3 (2001)
161. Structural analysis of Escherichia coli endonuclease VIII: its covalent reaction Zharkov, D.O., Golan, G., Gilboa, R., Fernandes, A.S., Gerchman, S.E., Kycia, J.H., Rieger, R.A., Grollman, A.P., and Shoham, G. EMBO J 21, 789-800 (2002).
162. Structure of Formamidopyrimidine-DNA Glycosylase Covalently Complexed to Golan, G., Fernandes, A.S., Gerchman, S.E., Matz, E., Kycia, J.H., Grollman, A.P., and Shoham, G. J. Biol. Chem. 277, 19811-19816 (2002).
163. Combining structural and bioinformatics methods for the analysis of functionally Free Rad. Biol. Med. 32, 1254-1263 (2002).
164. Tamoxifen-DNA adducts: biomarkers for drug-induced endometrial cancer. Shibutani, In: Biomarkers of Environmentally Associated Disease. Technologies, Concepts, and Perspectives. Wilson, S.H., Suk, W.A. (Eds.), CRC Press LLC, 127-137 (2002). 165. Translesion Synthesis by Human DNA Polymerase κ on a DNA Template Containing a Single Stereoisomer of dG-(+)- or dG-(-)-anti-N2-BPDE (7,8-Dihydroxy-anti-9, 10-epoxy-7,8,9,10-tetrahdrobenzo[a]pyrene). Suzuki, N., Ohashi, E., Kolbanovskiy, A., Geacintov, N.E., Grollman, A.P., Biochemistry 41, 6100-6106 (2002).
166. Mutagenic Events in Escheriachia coli and Mammalian Cells Generated in Response to Acetylaminofluorene-Derived DNA Adducts Positioned in the Nar 1 Restriction Enzyme Site. Tan, X., Suzuki, N., Grollman, A.P. and Shibutani, S. Biochemistry 41, 14255-14262 (2002).
167. Botanical Medicines – The Need for New Regulations. New England Journal of Medicine 347(25), 2073-2076 (2002)
168. Genotoxic Mechanism for the Major Acrolein-derived Deoxyguanosine Adduct in Yang, I-Y., Johnson, F., Grollman, A.P. and Moriya, M. Chemical Research in Toxicology 15(2), 160-164 (2002)
169. Structure of DNA polymerase β with the mutagenic DNA lesion 8- oxodeoxyguanine reveals structural insights into its coding potential. Krahn, J.M., Beard, W.A., Miller, H., Grollman, A.P. and Wilson, S.H. Structure 11, 121-127 (2003).
170. The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation- Rosenquist, T.A., Zaika, E., Fernandes, A.S., Zharkov, D.O., Miller, H. and Grollman, A.P. DNA Repair 2, 581-591 (2003).
171. DNA Repair Investigations Using siRNA. DNA Repair 2, 759-763 (2003).
172. Energetics of Lesion Recognition by DNA Repair Protein: Thermodynamic Characterization of Formamidopyrimidine-glycosylase (Fpg) Interactions with Damaged DNA Duplexes. Minetti, C.A.S.A., Remeta, D.P., Zharkov, D.O., Plum, G.E., Johnson, F., Grollman, A.P. and Breslauer, K.J. J. Mol. Biol. 328, 1047-1060 (2003).
173. Structural characterization of the Fpg family of DNA glycosylases. Zharkov, D., Shoham, G. and Grollman, A.P. DNA Repair 2, 839 - 862 (2003).
174. Crystallographic Characterization of an Exocyclic DNA Adduct: 3, N4-etheno-2’- deoxyctydine in the Dodecamer 5’-CGCGAATTεCGCG-3’ Freisinger, E., Fernandes, A., Grollman, A.P., and Kisker, C. J. Mol. Biol. 329, 685-697 (2003).
175. Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen. Shibutani, S., Suzuki, N., Y. R. Santosh Laxmi, Schild, L. J., Divi, R. L., Grollman, A. P., and Poirier, M. C. Cancer Res. 63, 4402-4406 (2003)
176. The Thermodynamics of Template-Directed DNA Synthesis: Base Insertion and Minetti, C.A.S.A., Remeta, D.P., Miller, H., Gelfand, C.A., Plum, G.E., Grollman, A.P., and Breslauer, K.J. Proc. Natl. Acad. Sci USA 100, 14719-14724 (2003)
Marcus, D.M., Grollman, A.P.
Science 301(5640), 1669-71 (2003)
178. Stereoselective excision of thymine glycol from oxidatively damaged DNA. Miller, H., Fernandes, A., Zaika, E., McTigue, M., Torres, C., Wente, M., Iden, C., Grollman, A.P. Nucleic Acids Research 32, No. 1, 338-345 (2004)
preliminary crystallographic analysis of endonuclease VIII in Golan, G., Zharkov, D.O., Fernandes, A.S., Zaika, E., Kycia, J.H., Wawrzak, Z., Grollman, A.P., Shoham, G. Acta Crystallographics 60, 1476-1480 (2004)
180. Lesion (in)tolerance reveals insights into DNA replication fidelity Freisinger, E., Grollman, A.P., Miller, H., Kisker, C. The EMBO Journal 23, 1494-505 (2004)
181. Substrate Discrimination by Formamidopyrimidine-DNA Glycosylase - A Zaika, E. I., Perlow, R.A., Matz, E., Broyde, S., Gilboa, R., Grollman, A.P., Zharkov, D.O. Journal of Biological Chemistry 279, 4849 – 4861 (2004)
182. “Knock down” of DNA polymerase β by RNA interference: recapitulation of null Polosina, Y.Y., Rosenquist, T.A., Grollman, A.P., Miller, H. DNA Repair 3, 1469-1474 (2004)
Encyclopedia of Biological Chemistry, 1, 694-8 (2004)
184. Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells. Yasui, M., Dong, H., Bonala, R.R., Suzuki, N., Ohmori, H., Hanaoka, F., Johnson, F., Grollman, A.P., Shibutani, S. Biochemistry 43, 15005-13. (2004)
185. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon Dong, H., Bonala, R.R., Suzuki, N., Johnson, F., Grollman, A.P.,
Shibutani, S.
Biochemistry 43,15922-8. (2004)
186. Mechanism of frameshift (deletion) generated by acetylaminofluorene-derived Shibutani, S., Suzuki, N., Grollman, A.P. Biochemistry 43, 15929-35. (2004)
187. Substrate discrimination by formamidopyrimidine-DNA glycosylase: distinguishing interactions within the active site. Perlow-Poehnelt, R.A., Zharkov, D.O., Grollman, A.P., Broyde, S.
Biochemistry 43, 16092-105 (2004)
on dietary supplements use: The need for new Grollman, A.P.
Thromb Res. 117, 185-92 (2005)
189. Endemic nephropathy: the case for chronic poisoning by aristolochia. Hranjec, T., Kovac, A., Kos, J., Mao, W., Chen, J.J., Grollman, A.P.,
Jelakovic’, B.
Croat Med J. 46:116-25 (2005)
190. Mutagenic specificity of 2-acetylaminonaphthalene-derived DNA adduct in Tan, X., Bonala, R.R., Suzuki, N., Johnson, F., Grollman, A.P.,
Shibutani, S.
Chem Biol Interact. 152, 131-8 (2005)
191. The DNA trackwalkers: principles of lesion search and recognition by DNA Mutation Research 33, 5006-16 (2005)
192. Dynamic behavior of DNA base pairs containing 8-oxoguanine. Cheng, X., Kelso, C., Hornak, V., de los Santos, C., Grollman, A.P.,
Simmerling, C.
J Am Chem Soc. 127, 13906-18 (2005).
193. Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates Golan, G., Zharkov, D.O., Feinberg, H., Fernandes, A.S., Zaika, EI, Kycia, J.H., Grollman, A.P., Shoham, G. Nucleic Acids Res. 33, 5006-16 (2005)
194. Proteomic approach to identification of proteins reactive for abasic sites in DNA. Rieger, R.A., Zaika, EI, Xie, W., Johnson, F., Grollman, A.P., Iden, C.R.,
Zharkov, D.O.
Molecular and Cellular Proteomics 5, 858-67 (2006)
195. Structure of T4 Pyrimidine Dimer Glycosylase in a Reduced Imine Covalent Golan, G., Zharkov, D.O., Shoham, G., Grollman, A.P., Fernandes, A.,
Dodson, M.L., McCullough, A.K., Lloyd, R.S.
J Mol Biol 362(2), 241-58 (2006)
196. Catalytic mechanism of Escherichia coli endonuclease VIII: Roles of the Kropachev, K.Y., Zharkov, D.O., Grollman, A.P. Biochemistry 45, 12039-49 (2006)
197. RNA aptamers selected against DNA polymerase β inhibit the polymerase activities of DNA polymerase β and DNA polymerase κ Gening, L.V., Klincheva, S.A., Reshetnjak, A., Grollman, A.P.
and Miller, H.
Nucleic Acids Res. 34(9):2579-86 (2006)
analysis of the binding mode of 8-oxoguanine to Song, K., Hornak, V., de los Santos, C., Grollman, A.P., Simmerling, C.
Biochemistry 45 (36), 10886-94 (2006)
199. Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/PAGE analysis.
Dong, H., Suzuki, N., Torres, M.C., Bonala, R.R., Johnson, F.,
Grollman, A.P., Shibutani, S.
Drug Metab Dispos 34 (7), 1122-7 (2006)
200. Science and government. Review for NCCAM is overdue. Science 313(5785), 301-2 (2006)
201. Transplantation for Chinese herb nephropathy. Morrissey, P.E., Gautam, A., Yang, A., Grollman, A.P., Esparza, A., Clin Transpl. 560 (2006)
202. TGF-β, HEY1 and chromatin structure regulation in epithelial-mesenchymal Blumenberg, M., Gao, S., Dickman, K.G., Grollman, A.P., Bottinger, E.P.,
Zavadil, J.
Cells Tissues Organs 185(1-3), 162-74 (2007)
203. Aristolochic acid and the etiology of (Balkan) endemic nephropathy. Grollman, A.P., Shibutani, S., Moriya, M. , Miller, F., Wu, L., Moll, U.,
Suzuki, N., Fernandes, A., Medverec, Z., Jakovina, K., Brdar, B., Slade,
N., Rieger, R., Vukelic, M., Jelakovic’, B.
Proc Natl Acad Sci USA 104(29), 12129-34 (2007)

204. Selective Toxicity of Aristolochic Acids I and II. Shibutani, S., Dong, H., Suzuki, N., Ueda, S., Miller, F., Grollman, A.P. Drug Metab Dispos. 35(7), 1217-22 (2007)
205. Molecular simulations reveal a common binding mode for glycosylase binding of Song, K., Kelso, C., de los Santos, C., Grollman, A.P., Simmerling, C. J Am Chem Soc. 129(47), 14536-7 (2007)
206. Role of environmental toxins in endemic (Balkan) nephropathy. J Am Soc Nephrol. 18(11), 2817-23 (2007)
207. Limitations of "evidence-based indications" for herbs. Mayo Clin Proc. 82(11), 1433 (2007)
208. Chromatin structure regulation in transforming growth factor-beta-directed Blumenberg, M., Gao, S., Dickman, K.G., Grollman, A.P., Bottinger, E.P., Cells Tissues Organs. 185(1-3), 162-74 (2007)
Song, K., Hornak, V., de los Santos, C., Grollman, A.P., Simmerling, C. J Comput Chem. 29(1), 17-23 (2008)
210. Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase. Sidorenko, V.S., Grollman, A.P., Jaruga, P., Dizdaroglu, M., Zharkov, D.O. FEBS J. 276(18), 5149-62 (2009)
211. An improved reaction coordinate for nucleic acid base flipping studies Song, K., Campbell, A.J., Bergonzo, C., de los Santos, C., Grollman, A.P., J. Chem. Theory Comput. 5 (11), 3105–3113 (2009)
212. DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis Attaluri, S., Bonala, R.R., Yang, I.Y., Lukin, M.A., Wen, Y., Grollman A.P.,
Moriya, M., Iden, C.R., Johnson, F.
Nucleic Acids Res. 38(1), 339-52 (2010)
214. Aristolochic acid nephropathy: an environmental and iatrogenic disease Grollman A.P., Scarborough, J., Jelakovic´, B.
Advances in Molecular Toxicology 3. Ed. Fishbein JC.
Elsevier: Amsterdam, The Netherlands 211-222 (2009)
215. Detoxification of aristolochic acid I by O-demethylation: Less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents. Shibutani, S., Bonala, R.R., Rosenquist, T., Rieger, R., Suzuki, N.,
Johnson, F., Miller, F., Grollman, A.P.
Int J Cancer 127(5), 1021-7 (2010)
216 Nephrotoxicity of natural products: aristolochic acid and fungal toxins Dickman, K.G. and Grollman, A.P. Comprehensive Toxicology v7, Renal Toxicology (2nd ed), Schnellmann, Elsevier: Oxford 433-458 (2010) 217. Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse. Rosenquist, T.A., Einolf, H.J., Dickman K.G., Wang. L., Smith. A., Drug Metab Dispos. 38(5), 761-8 (2010)
218. TP53 mutational signature for aristolochic acid: an environmental carcinogen. Moriya, M., Slade, N., Brda,r B., Medverec, Z., Tomic, K., Jelakovic’, B., Wu, Truong, S., Fernandes, A. and Grollman, A.P. Int J Cancer 129(6), 1532-6 (2011)
219. Aristolactam-DNA adducts in the renal cortex: Biomarkers of environmental Jelakovic’, B., Karanovic, S., Vukolic-Lela, I., Miller, F., Edwards, K.,
Nikolic J., Tomic, K., Slade, N., Brdar, B., Turesky, R., Stipancic, Z.,
Dittrich,D., Grollman, A.P., and Dickman, K.G.
Kidney International 81, 559-567 (2011)
220. Energetic preference of 8-oxoG: eversion pathways in a DNA Bergonzo, C., Campbell, A.J., de Los Santos, C., Grollman, A.P., Simmerling, C. J Am Chem Soc. 133, 14504–14506 (2011).
221. Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts. Sidorenko V.S., Yeo J-E, Bonala R.R., Johnson F, Scharer O.D., and Grollman A.P. Nucleic Acids Res, 40 (6): 2494-2505 (2012)
222. Aristolochic acid-associated urothelial carcinoma in Taiwan. Chen, C-H, Dickman, K.G., Moriya, M., Zavadil, J., Sidorenko, V.S., Edwards, K.L., Gnatenko, D.V., Wu, L., Turesky, R.J.K., Wu, X-R, Pu, Y-S, and Grollman, A.P. Proc Natl. Acad Sci, 109 (21): 8241-8246 (2012)
The Consequences of Ineffective Regulation of Dietary Supplements. Arch Intern Med, 172(13):1035-1036 (2012)
analysis of aristolochic acid-derived DNA adducts. Romanov V., Sidorenko V., Rosenquist T.A., Whyard T., and Grollman
A.P. Anal Biochem, 427:49-51 (2012)
225. Biomonitoring of human AL-DNA adducts in human tissues using ultra- performance liquid chromatography/ion-trap mass spectroscopy. Yun B., Rosenquist T., Sidorenko V., Iden C.R., Chen C.H., Pu Y.S.,
Bonala R., Johnson F., Dickman K.G., Grollman A.P., and Turesky R.J.
Chem Res Toxicol, 25:1119-31 (2012)
Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease. Environmental and Molecular Mutagenesis, 54(1): 1-7 (2013)
227. Aristolochic Acid-Induced Upper Tract Urothelial Carcinoma in Taiwan: Clinical Chen C-H, Dickman K.G., Huang C-Y., Moriya M., Shun C-T., Tai H-C.,
Huang K-H., Wang S-M., Lee Y-J., Grollman A.P., Pu Y-S.
Int J Cancer, 133(1): 14-21 (2013)
228. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Killela P J, Reitman Z J, Jiao Y, Bettegowda C, Agrawal N, Diaz Jr. L A, Friedman A H, Friedman H, Gallia G L, Giovanella B C, Grollman A P, He T-C, He Y, Hruban R H, Jallo G I, Mandahl N, Meeker A K, Mertens F, Netto G J, Rasheed B A, Riggins G J, Rosenquist T A, Schiffman M, Shih l-M, Theodorescu D, Torbenson M S, Velculescu V E, Wang T-L, Wentzensen N, Wood L D, Zhang M, McLendon R E, Bigner D D Kinzler K W, Vogelstein B, Papadopoulos N, Yan H PNAS, 110(15): 6021-6026 (2013)
229. Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid. Hollstein M., Moriya M., Grollman A.P., Olivier M. Mutat Res S1383-5742, (2013) Feb 17, PMID 23422071 230. Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole Hoang, M.L., Chen, C-H., Sidorenko, V.S., He, J., Dickman, K.G., Yun, B.H., Moriya, M., Niknafs, N., Douville, C., Karchin, R., Turesky, R.J., Pu, Y-S., Vogelstein, B., Papadopoulos, N., Grollman, A.P., Kinzler, K.W., Rosenquist, T.A. Sci Transl Med (2013) in press 231. Human Formalin-Fixed Paraffin-Embedded Tissues: An Untapped Specimen for Biomonitoring of Carcinogen DNA Adducts by Mass Spectrometry. Yun, B.H., Rosenquist, T.A., Nikolić, J. Dragiceivić, D., Tomić, K., Jelaković, B., Dickman K.G., Grollman A.P., Turesky R.J. Analytical Chem, 85(9): 4251-4258 (2013)

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Olympic movement anti-doping code 1999

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PRESENT: Councillor Colin Lambert (in the Chair); Councillor Ashley Dearnley, Sheila Downey, Gladys Rhodes-White and Jim Taylor (RMBC); Dr Richard Verity, Dr Chris Duffy and Lesley Mort (HMRCCG); S. Anwar and Dr Marian Corns (Voices4Wellbeing); C Davis (Healthwatch). OFFICERS: Mark Hardman and Alison Leonard (RMBC); Michelle Loughlin and Wendy Meston (RMBC/NHS-HMR). Also in Attendance – Counci

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