Die Struktur von Tadalafil erlaubt eine selektive Bindung an die Bindungsstelle der PDE5 und minimiert gleichzeitig die Interaktion mit PDE6, was visuelle Nebenwirkungen einschränkt. Seine Verteilung im Organismus erfolgt breit, wobei das Verteilungsvolumen etwa 63 Liter beträgt. Über 90 % des Wirkstoffs sind an Plasmaproteine gebunden. Die Wirkung bleibt unabhängig von der Nahrungsaufnahme konstant. Der Abbauweg über CYP3A4 kann durch Hemmer wie Ritonavir oder Ketoconazol verlangsamt werden, was die Plasmakonzentrationen deutlich erhöht. In diesem Kontext wird cialis 20mg preis häufig in Bezug auf pharmakokinetische Wechselwirkungen erwähnt.

Microsoft word - preventive medications for columbia university hdhp final 11 7 _2_.docx

Preventive Medications for Columbia University HDHP* -Thyroid Prescriptions -Immunosuppressant Agents  azathioprine (Imuran)  cyclosporine (Sandimmune)  cyclosporine, modified (Gengraf, Neoral)  mycophenolate mofetil (CellCept)  mycophenolic acid (Myfortic)  sirolimus (Rapamune)  tacrolimus (Prograf)
-Hepatitis C Prescriptions

-Heart disease and stroke
o Over-the-counter aspirin medicines, 81 mg or 325 mg o Warfarin (Coumadin, Jantoven) o Heparin and low-molecular-weight heparin: [enoxaparin (Lovenox); fondaparinux o ACE inhibitors and combinations: benazepril (Lotensin, Lotensin HCT); enalapril (Vasotec, Vaseretic); fosinopril (Monopril, Monopril-HCT); lisinopril (Prinivil, Prinzide, Zestril, Zestoretic); quinapril (Accupril, Accuretic); ramipril (Altace) o ACE receptor blockers and combinations: candesartan (Atacand, Atacand HCT); eprosartan (Teveten, Teveten HCT); irbesartan (Avapro, Avalide); losartan (Cozaar, Hyzaar); telmisartan (Micardis, Micardis HCT); valsartan (Diovan, Diovan HCT) o Beta blockers and combinations: atenolol (Tenormin, Tenoretic); bisoprolol (Zebeta, Ziac); metoprolol (Lopressor, Toprol-XL); nebivolol (Bystolic™); propranolol (Inderaol LA, InnoPral XL) o Calcium channel blockers: amlodipine (Norvasc); diltiazem (Cardizem, Cartia XT, Tiazac); nifedipine (Adalat, Procardia); nisoldipine (Sular); verapramil (Calan, Covera-HS, Isoptin SR, Verelan) o Diuretics and combinations: amiloride (Midamor); hydrochlorothiazide; indapamide; metolazone (Zaroxolyn); spironolactone (Aldactone); terazosin (Hytrin); triamterene-HCTZ (Dyazide, Maxzide) o Miscellaneous medicines and combinations: aliskiren (Tekturna); carvedilol (Coreg); clonidine (Catapres, Combipres, Clorpres); doxazosin (Cardura); enalapril-felodipine; hydralazine (Apresoline); amlodipine/benazepril (Lotrel); amlodipine/valsartan (Exforge) o HMG-coA reductase inhibitors: atorvastatin (Lipitor); lovastatin (Mevacor, Altoprev); pravastatin (Pravachol); rosuvastatin (Crestor); simvastatin (Zocor) o Other agents: cholestyramine (Prevalite, Questran); colesevelam (WelChol); colestipol (Colestid); gemfibrozil (Lopid); fenofibrate (Fenoglide™, Lipofen, TriCor); ezetimibe (Zetia); exetimibe/simvastatin (Vytorin); omega-3-acid ethyl esters (Omacor) o niacin (Niacor, Niaspan); niacin/lovastatin (Advicor); niacin ER/simvastatin  montelukast (Singulair)  zafirlukast (Accolate)  zileutron (Zyflo CR)  alendronate (Fosamax, Fosamx Plus D)  calcitonin (Fortical, Miacalcin)  ibandronate (Boniva)  raloxifene (Evista)  risedronate (Actonel)  zoledronic acid (Reclast)  aspart (NovoLog)  detemir (Levemir)  glargine (Lantus)  glulisine (Apidra)  lispro (Humalog)  insulin (Humulin, Novolin)  exenatide (Byetta)  glimepiride (Amaryl)  glipizide and combinations (Glucotrol, Metaglip)  glyburide and combinations (DiaBeta, Glynase, Glucovance)  liraglutide (Victoza)  metformin (Fortamet, Glucophage, Glumetza™)  nateglinide (Starlix)  pioglitazone and combinations (Actos, Duetact™, ACTOplus met)  repaglinide (Prandin)  rosiglitazone and combinations (Avandia, Avandaryl™, Avandamet)  saxagliptin (Onglyza™)  sitagliptin and combinations (Januvia™, Janumet™)
*ONLY EXAMPLE MEDICINES ARE LISTED, THIS IS NOT A COMPLETE LISTING OF COVERED MEDICINES.
Medco Health Solutions, Inc., is the company that manages the prescription drug benefit for your
employer or health plan.
Please note: Brand names are shown in italics in each category.
All rights in the product names of all third-party products appearing here, whether or not appearing with
the trademark symbol, belong exclusively to their respective owners.

Source: http://hr.columbia.edu/files_humanresources/imce_shared/_for_Columbia_University_HDHP_FINAL_11_7__2_.pdf