Microsoft word - publication2004

Brown M, Jacobs T, Eickolt B, Ferrari G, Teo M, Monfries C, Qi RZ, Leung T, Lim L
and Hall C (2004). α2-Chimaerin, Cdk5/p35 and its target CRMP-2 are essential
components in Sema 3A-induced growth-cone collapse. J. Neurosci. 24(41):8994-9004.
Bu X, Wu X, Ng NLJ, Mak CK, Qin C and Guo Z (2004). Synthesis of gramicidin S
and its analogues via an on-resin macrolactamization assisted by a predisposed
conformation of the linear precursors. J. Org. Chem. 69: 2681–2685.
Carles M and Ip NY (2004). Use of silicon-based oligonucleotide chip in authentication
of toxic Chinese medicine. In: Herbal medicine: Molecular Basis in Health and Disease
Management, pp. 857-872 (L. Packer, C.N. Ong and B. Halliwell, ed). Invited. Chan ASL and Wong YH (2004). Epidermal growth factor differentially augments
Gi-mediated stimulation of c-Jun N-terminal kinase activity. Br. J. Pharmacol. 142:
Chan ASL and Wong YH (2004). Gβγ signaling and Ca2+ mobilization co-operate
synergistically in a Sos and Rac-dependent manner in the activation of c-Jun N-terminal
kinase by Gq-coupled receptors. Cell. Signal. 16: 823-836.
Chan WM, Siu WY, Lau A and Poon RYC (2004). How many mutant p53 molecules are
needed to inactivate a tetramer? Mol. Cell. Biol. 24: 3536-51.
Chang DC (2004). Electroporation and electrofusion. In: Encyclopedia of Molecular
Cell Biology and Molecular Medicine. (Ed. by R.A. Meyers, Wiley-VCH Publishers, Cheng JC, Miller AL and Webb SE (2004). The organization and function of
microfilaments during epiboly in zebrafish embryos. Dev. Dyn. 231: 313-323.
Cheung N, So CW, Yam JW, So CK, Poon RYC, Jin DY and Chan LC (2004).
Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukemia.
10. Cheung NS, Choy MS, Halliwell B, Teo TS, Bay BH, Lee AY, Qi RZ, Koh VH,
Whiteman M, Koay ES, Chiu LL, Zhu HJ, Wong KP, Beart PM and Cheng HC (2004). Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrance fraction. Cell. Mol. Life Sci. 61: 1926-1934. 11. Cheung NS, Koh CH, Bay BH, Qi RZ, Choy MS, Li QT, Wong KP and Whiteman M
(2004). Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons. Biochem. Biophys. Res. Commun. 315: 408-417. 12. Cheung PY, Zhang Y, Long J, Lin S, Zhang MJ, Jiang Y and Wu Z (2004). P150Glued,
dynein and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs. J. Biol. Chem. 279: 45308-45311. (accelerated publication). 13. Cheung ZH and Ip NY (2004). Cdk5: mediator of neuronal death and survival.
Neurosci. Lett. 361: 47-51. Invited. 14. Chou GX, Dong TTX, Tsim KWK, Yu ZL and Wang ZT (2004). Preparation methods
for detection of gentiopicrin in Radix Gentianae. Research and Practice of Chinese 15. Chu KM, Chow KBS, Wong YH and Wise H (2004). Prostacyclin receptor-mediated
activation of extracellular signal-regulated kinases 1 and 2. Cell. Signal. 16: 477-486. 16. Chung KK and Dawson TM (2004). Parkin and HSP70 sacked by BAG5. Neuron. 44:
17. Chung KK, Thomas B, Li X, Pletnikova O, Troncoso JC, Marsh L, Dawson VL and
Dawson TM (2004). S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science. 304(5675): 1328-31. 18. Dai WM, Tachi Y, Nishimoto SI, Zhong XF and Guo ZH (2004). Synthesis and
cytotoxicity of enediyne prodrugs with 3-Hydroxy-4-(arylmethylidene) -cyclodeca- 1,5-diyne scaffolds. Lett. Drug Des. Discov. 1: 69-72. 19. Dai WM, Yeung KKY and Wang YQ (2004). The first example of atropisomeric
amide-derived P,O-ligabds used for an asymmetric heck reaction. Tetrahedron. 60: 4425-4430. 20. Dai WM, Zhang Y and Zhang Y (2004). Synthesis of atropisomeric 2,8-dioxygenated
N,N-diisopropyl-1-naphthamides via kinetic resolution under the sharpless asymmetry dihydroxylation conditions. Tetrahedron: Asymmetry. 15: 525-535. 21. Feng W, Long J, Fan JS, Tetsuya S and Zhang MJ (2004). The tetrameric L27 domain
complex as an organization platform for supramolecular assemblies. Nat. Struct. & Mol. 22. Fu AKY, Fu WY, Ng AKY, Chien WWY, Ng YP, Wang J and Ip NY (2004).
Cyclin-dependent kinase 5 phosphorylates STAT3 and regulates its transcriptional activity. Proc. Natl. Acad. Sci. USA 101: 6728-6733. 23. Hazari A, Lowes V, Chan JHP, Wong CSS, Ho MKC, and Wong YH (2004).
Replacement of the α5 helix of Gα16 with Gαs-specific sequences enhances promiscuity of Gα16 toward Gs-coupled receptors. Cell. Signal. 16: 51-62. 24. Ho MKC, Chan JHP, Wong CSS and Wong YH (2004). Identification of a stretch of six
divergent amino acids on the α5 helix of Gα16 as a major determinant for the promiscuity and efficiency of receptor coupling. Biochem. J. 380: 361-369. 25. Huang P, Gilmore E, Kultgen P, Barnes P, Migram SL and Stutts MJ (2004). Local
regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium. Proc Am Thorac Sco. 1: 33-37. 26. Kam AYF, Chan ASL and Wong YH (2004). κ-opioid receptor signals through Src and
focal adhesion kinase to c-Jun N-terminal kinases in transfected COS-7 cells and human monocytic THP-1 cells. J. Pharmacol. Exp. Therapeu. 310: 301-310. 27. Kam AYF, Chan ASL and Wong YH (2004). Phosphatidylinositol-3 kinase is
distinctively required for µ- but not κ-opioid receptor-induced activation of c-Jun N-terminal kinase. J. Neurochem. 89: 391-402 28. Lai KO, Chen Y, Po HM, Lok KC, Gong K and Ip NY (2004). Identification of the
Jak/Stat proteins as novel downstream targets of EphA4 signaling in muscle: implications in the regulation of acetylcholinesterase expression. J. Biol. Chem. 279: 13383-13392. 29. Lao SC, Li SP, Kan KKW, Li P, Wan JB, Wang YT, Dong TTX and Tsim KWK (2004).
Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction. Analytica Chimica Acta. 526: 131-137. 30. Lee HHC, Choi RCY, Ting AKL, Siow NL, Jiang JXS, Massoulié J and Tsim KWK
(2004). Transcriptional regulation of acetylcholinesterase-associated collagen ColQ: differential expression in fast- and slow-twitch muscle fibers is driven by distinct promoters. J. Biol. Chem. 279: 27098-27107. 31. Lee KW, Ho SM, Wong CH, Webb SE and Miller AL (2004). Characterization of
Mid-Spindle Microtubules during Furrow Positioning in Early Cleavage Period Zebrafish Embryos. Zygote. 12:221-230. 32. Li SP and Tsim KWK (2004). The biological and pharmacological properties of
Cordyceps sinensis, a traditional Chinese medicine, that has broad clinical applications. In: Herbal Medicines: Molecular Basis of Biological Activity and Health. Packer et al. ed. Marcel Dekker Inc. New York. 33. Li SP, Li P, Lai CM, Gong YX, Kan KKW, Dong TTX, Tsim KWK and Wang YT
(2004). Simultaneous determination of ergosterol nucleosides and their bases from nature and cultured Cordyceps by pressurized liquid extraction and high-performance liquid chromatography. J. Chromatogr. A 1036: 239-243. 34. Li SP, Song ZH, Dong TTX, Lo CK, Zhu SQ and Tsim KWK (2004). Distinction of
water-soluble constituents from natural and cultured Cordyceps mycelia by capillary electrophoresis. Phytomedicine. 11: 684-690. 35. Li Z, David G, Hung KW, DePinho RA, Fu AKY and Ip NY (2004). Cdk5/p35
phosphorylates mSds3 and regulates mSds3-mediated repression of transcription. J. Biol. 36. Lim ACB, Hou Z, Goh CP and Qi RZ (2004). Protein kinase CK2 is an inhibitor of the
neuronal Cdk5 kinase. J. Biol. Chem. 279(45):46668-46673. 37. Lim ACB, Tiu SY, Li Q and Qi RZ (2004). Direct regulation of microtubule dynamics
by protein kinase CK2. J. Biol. Chem. 279(6): 4433-4439. 38. Ling KKY, Siow NL, Choi RCY, Ting AKL, Kong LW and Tsim KWK (2004). ATP
potentiates agrin-induced AChR aggregation in cultured myotubes: activation of RhoA in P2Y1 nucleotide receptor signaling at vertebrate neuromuscular junctions. J. Biol. 39. Liu AMF and Wong YH (2004). Activation of nuclear factor κB by the G16-coupled
adenosine A1 receptor involves c-Src, PKC and ERK signaling. J. Biol. Chem. 279: 53196-53204. 40. Lo RKH and Wong YH (2004). Signal transducer and activator of transcription 3
activation by the δ-opioid receptor via Gα14 involves multiple intermediates. Mol. 41. Lo WS, Lau CF, Xuan Z, Chan A, Feng GY, He L, Cao ZC, Liu H, Luan QM and Xue H
(2004). Association of SNPs and haplotypes in GABAA receptor β2 gene with schizophrenia. Mol Psychiatry 9: 603-608. 42. Luo KQ and Chang DC (2004). The gene-silencing efficiency of siRNA is strongly
dependent on the local structure of mRNA at the targeted region. Biochem Biophys Res 43. New DC and Wong YH (2004). Characterization of CHO cells stably expressing a
Gα16/z chimera for high-throughput assays. Assay Drug Dev. Tech. 2: 269-280. 44. Ng CP, Lee HC, Ho CW, Arooz T, Siu WY, Lau A and Poon RYC (2004). Differential
mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains. J. Biol. Chem. 279: 8808-19. 45. Okada SF, O'Neal WK, Huang P, Nicholas RA, Ostrowski LE, Craigen WJ, Lazarowski
ER and Boucher RC (2004). Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells. J Gen Physiol. 124: 513-526. 46. Pan Q, Ip FCF, Ip NY, Zhu HX and Min ZD (2004). Activity of macrocyclic jatrophane
diterpenes from Euphorbia kansui in a TrkA fibroblast survival assay. J. Nat. Prod. 67: 1548-1551. 47. Pi R, Li W, Lee NT, Chan HH, Pu Y, Chan LN, Sucher NJ, Chang DC, Li M and Han
YF (2004). Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways. J. Neurochem. 91(5): 1219-30. 48. Qi RZ, Ching YP, Kung HF and Wang JH (2004). α-Chimaerin exists in a functional
complex with the Cdk5 kinase in brain. FEBS Lett. 561(1-3): 177-180. 49. Qin C, Bu X, Zhang X, Ng NLJ and Guo Z (2004). Optimization of antibacterial cyclic
decapeptides. J. Comb. Chem. 6:398–406. 50. Romorini S, Piccoli G, Jiang M, Grossano P, Tonna N, Passafaro M, Zhang MJ and Sala
C (2004). A functional role of PSD-95/GKAP complex in regulating Shank assembly and stability to synapses. J. Neurosci. 24: 9391-9404. 51. Rui Y, Xu Z, Lin SY, Li QX, Rui HL, Luo W, Zhou HM, Cheung PY, Wu Z, Ye ZY, Li P,
Han JHM and Lin SC (2004). Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation. EMBO J. 23: 4583-94. 52. Song Y, Kesuma D, Wang J, Deng Y, Duan J, Wang JH and Qi RZ (2004). Specific
inhibition of cyclin-dependent kinases and cell proliferation by harmine. Biochem. Biophys. Res. Commun. 317(1):128-132. 53. Siu WY, Lau A, Arooz T, Chow JPH, Ho HTB and Poon RYC (2004). Topoisomerase
poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms. Mol. Cancer Therap. 3: 621-32. 54. Song Y, Kesuma D, Wang J, Deng Y, Duan J, Wang JH and Qi RZ (2004). Specific
inhibition of cyclin-dependent kinases and cell proliferation by harmine. Biochem. Biophys. Res. Commun. 317(1): 128-132. 55. Song ZH, Lo CK, Dong TTX, Li OTW, Ji ZN, Haines CJ, Kung SD and Tsim KWK
(2004). Chemical and biological assessment of a traditional Chinese herbal decoction prepared from Radix Astragali and Radix Angelica Sinensis: orthogonal array design to optimize the extraction of chemical constituents. Planta Medica. 70: 1222-1227. 56. Sun L, Liu L, Yang XJ and Wu Z (2004). Akt binds Prohibitin 2 and relieves its
repression on MyoD and muscle differentiation. J. Cell. Sci. 117:3021-3029. (featured in the editorial highlights). 57. Sun LP, Huang XH and Dai WM (2004). Stepwise and One-Pot Coupling-
Heteroannulation Approach toward 2-Substituted C4-Aminoindoles and C5-, C6-, and C7-Nitroindoles. Tetrahedron. 60: 10983-10992. 58. Tang W, Sun X, Fang JS, Zhang MJ and Sucher NJ (2004). Flavonoids from Radix
Scutellariae as potential stroke therapeutic agents by targeting the second postsynaptic density 95 (PSD-95)/disc large/zonula occludens-1(PDZ) domain of PSD-95. Phytomed. 11: 277-284. 59. Tian YJ, New DC, Yung LY, Allen RA, Slocombe PM, Twomey BM, Lee MMK and Wong YH (2004). Differential chemokine activation of CCR1-regulated pathways:
selective activation of Gα14-coupled pathways. Eur. J. Immunol. 34: 785-795. 60. Tsang SY and Xue H (2004). Development of effective therapeutics targeting the
GABAA receptor: naturally occurring alternatives. Current Pharm. Design. 10(9):1035-1044. 61. Tsim KWK and Kung SD (2004). Modernization of traditional Chinese medicine:
problems in safety and quality assurance. Vision of 2050: Agriculture in China. Edited by Tso et al. New York. 62. Tsim KWK, Choi RCY, Siow NL, Cheng AWM, Ling KKY, Tung EKK, Kong LW and
Barnard EA (2004). The role of P2Y1 nucleotide receptors in the formation and maintenance of the skeletal neuromuscular junctions. In: Cholinergic Mechanisms. A. Fisher and H. Soreq eds. Martin Dunitz, London. 63. Tung EKK, Choi RCY, Siow NL, Jiang JXS, Ling KKY, Simon J, Barnard EA and Tsim
KWK (2004). P2Y2 receptor activation regulates the expression of acetylcholinesterase
and acetylcholine receptor genes at vertebrate neuromuscular junction. Mol. Pharmacol.
66(4): 794-806.
64. Wan J, Sun L, Mendoza JW, Chui YL, Huang DP, Chen ZJ, Suzuki N, Suzuki S, Yeh WC, Akira S, Matsumoto K, Liu ZG and Wu Z (2004). Elucidation of the JNK pathway
mediated by Epstein-Barr virus encoded latent membrane protein 1. Mol. Cell Biol.
65. Wang YD, Sin WY, Xu GB, Yang HH, Wong TY, Pang XW, He XY, Zhang HG, Ng NLJ, Cheng CSS, Yu J, Meng L, Yang RF, Lai ST, Guo Z, Xie Y, Chen WF (2004). T cell
epitopes in severe acute respiratory syndrome (SARS)-CoV virus spike protein elicit
specific T cell immune response in recovered SARS patients. J. Virol. 78: 5612–5618.
66. Wen CM, Zhang ZH, Ma WP, Xu M, Wen ZL and Peng JR (2004). Genome-wide
identification of demal-enriched genes in zebrafish. Develop. Dynamics. 232: 171-179. 67. Woo RA and Poon RYC (2004). Activated oncogenes promote and cooperate with
chromosomal instability for neoplastic transformation. Gene Dev. 18:1317-30. 68. Woo RA and Poon RYC (2004). Gene mutations and aneuploidy: the instability that
causes cancer. Cell Cycle. 3: 1101-3. 69. Wu JL, Wu HF, Wei SY and Dai WM (2004). Highly regioselective wittig reactions of
cyclic ketones with a stabilized phosphorus ylide under controlled microwave heating. 70. Xu C, Xu, K, Gu H, Zheng R, Liu H, Zhang X, Guo Z and Xu B (2004). Dopamine as a
robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles. J. Am. Chem. Soc. 126:9938–9939. 71. Xu X, Xu K, Gu H, Zhong X, Guo Z, Zheng R, Zhang X and Xu B (2004).
Nitrilotriacetic acid modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins. J. Am. Chem. Soc. 126: 3392–3393. 72. Yu JCH, Min ZD and Ip NY (2004). Melia toosendan regulates PC12 cell differentiation
via the activation of a PKA-dependent ERK signaling pathway. NeuroSignals 13: 248-257. 73. Yu YY, Chen Y, Dai G, Chen J, Sun XM, Wen CJ, Zhao DH, Chang DC and Li CJ
(2004). The association of calmodulin with central spindle regulates the initiation of cytokinesis in HeLa cells. Int. J. Biochem. Cell Biol. 36(8): 1562-72. 74. Yu ZL, Feng DR and Liang C (2004). Pairwise Interactions of the Six Human MCM
Protein Subunits. J. Mol. Biol. 340:1197-1206. 75. Yuen JWF, So IYW, Kam AYF and Wong YH (2004). Regulation of signal transducer
and activator of transcription 3 by µ-opioid receptors in human neuroblastoma SH-SY5Y cells. NeuroReport. 15: 1431-1435. 76. Zhang X, Choi R, Tsim KWK and Wan DC (2004). Cloning and characterization of the
acetylcholinesterase gene in the chicken. In: Cholinergic Mechanisms. 757-760. A. Fisher and H. Soreq eds. Martin Dunitz, London. 77. Zhang Y, Yang ZM, Yuan F, Gu HW, Gao P and Xu B (2004). Molecular recognition
remolds the self-assembly of hydrogelators and increases the elasticity of the hydrogel by 106-Fold" J. Am. Chem. Soc. 126: 15028-15029. 78. Zhu Y, Stolz DB, Guo F, Ross MA, Watkins SC, Tan BJ, Qi RZ, Manser E, Li QT, Bay
BH, Teo TS and Duan W (2004). Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PRK1 in mammalian cells. FASEB J. 18: 1722-1724.


Evaluation of prochlorperazine buccal tablets (bukatel) and metoclopramide oral tablets in the treatment of acute emesis

Evaluation of Prochlorperazine Buccal Tablets (Bukatel) and Metoclopramide Oral Tablets in the Treatment of Acute Emesis SANJAY SINGH*, DEEPIKA R SHARMA**, ADARSH CHAUDHARY*** The dizziness associated with vertiginous disorders is often accompanied with nausea and/or vomiting. Anti-emetic effect of prochlorperazine (PCZ) is diminished by its low bioavailability owing to a signifi

Microsoft word - publications dr. eberhardt clinical research publications…

Dr. med. Reinhild Eberhardt, Ärztin für klinische Pharmakologie Publications – Reinhild Eberhardt M.D., Ph.D. Specialist in Clinical Pharmacology, Specialist in Laboratory Medicine 1. Cardiovascular Actions of Nicotine and Smoking Journal of the National Cancer Institute (1972) Vol. 48, No. 6 2. Absorption of Nicotine Through the Oral Mucosa Measurements of Nicotine Concentration in t

Copyright © 2010-2014 Medical Articles