Nome Comercial: ARTANE - Apresentação Composição Informações Técnicas Indicações Contra-indicações Precauções Interações Reações Adversas Posologia Superdosagem Bula Completa APRESENTAÇÕES COMPOSIÇÃO Cada comprimido contém cloridrato de triexifenidila 2 mg ou 5 mg. INFORMAÇÕES TÉCNICAS ARTANE (cloridrato de triexifen
Conversely, injection forms, though being painful and needing help of medical personnel for application, help to quickly achieve necessary concentration of preparation in blood buy antibiotics online Antibiotic is usually chosen in an empiric way (at random). But when choosing one is obligatory guided by definite rules.
Planb.cacontrol). Plan B® can be taken with a glass of water. If you vomit less than 1 hour after taking Plan B®, call your healthcare professional as you might need
You should not delay starting treatment. Plan B® is more effective the sooner you start taking the tablets after unprotected intercourse.
Important: If more than 72 hours (3 days) have passed since unprotected sex occurred, Plan B® may not be effective. See your health professional as soon as pos-
This leaflet is part III of a three-part "Product Monograph" published when Plan B® was approved for sale in Canada and is designed specifically for Consumers.
Although the risk of pregnancy is highest in the middle of the menstrual cycle (possibly as early as day 10 after the beginning of your last period), pregnancy can occur This leaflet is a summary and will not tell you everything about Plan B®. Contact your doctor or pharmacist if you have any questions about the drug. at other times during the menstrual cycle. Plan B® can be administered anytime during your monthly cycle if you are worried about an unwanted pregnancy. The treatment does not bring on menstruation. You may experience spotting a few days after taking Plan B®, but this is not a period. Your next menstrual period ABOUT THIS MEDICATION
should come on time (or a few days early or late). If your period is delayed more than a week or if you have any other cause for concern, talk to a health profes- What the medication is used for:
sional. More than occasional use (more than once in a menstrual cycle or more than once a month) may upset your menstrual cycle (period). Plan B® is a backup contraceptive.
Plan B® is not as effective in preventing pregnancy as the use of most other birth control methods (e.g. oral contraceptive pills, IUDs, implants or condoms, etc.).
Plan B® can prevent pregnancy after a contraceptive accident (such as a broken condom) or when no form of birth control was used. Treatment is most effective It should not be relied on for routine birth control by sexually active women.
if used in the first 72 hours (3 days) following unprotected sex .
Plan B® cannot terminate an existing pregnancy. Although there is no scientific evidence that Plan B® would harm a developing embryo, women who are already
Contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, vaginal bleeding, and may lead pregnant should not use this product.
Plan B® should not be used in place of regular contraception. It does not work as well as most other contraceptives used correctly.
SIDE EFFECTS AND WHAT TO DO ABOUT THEM
What it does:
Plan B® acts as an emergency contraceptive by preventing the release of an egg from the ovary, or preventing sperm and egg from uniting. In addition, Plan B®
Plan B® can cause temporary side effects in some women. These side effects generally do not last more than 24 hours.
may prevent the fertilized egg from attaching to the wall of the uterus. Plan B® is not effective once a pregnancy has started, that is once the fertilized egg has attached to the wall of the uterus. Plan B® does not cause an abortion.
• Nausea: This occurs in about 14 to 23% of women taking Plan B®.
Plan B® can be used following any unprotected act of sexual intercourse, including: • Vomiting: This occurs in about 6% of women taking Plan B®.
• Irregular menstrual bleeding: Some women may experience spotting after taking Plan B®. The majority of women will have their next menstrual period at the
• When a contraceptive method may have failed, including: expected time or early. When Plan B® is used repeatedly (more than once in a menstrual cycle, or more than occasional once a month use), menstrual changes may occur, including a shorter or longer cycle and a heavier or lighter period than normal. • Diaphragm or cap dislodgment, breakage or early removal Less common side effects: Breast tenderness, headache, dizziness, fatigue, lower abdominal pain, and diarrhoea. If the symptoms continue for more than 48 hours • Failure to withdraw before ejaculation or are severe, see your health professional.
• Miscalculation of the fertile period by women practising periodic abstinence SERIOUS SIDE EFFECTS, HOW OFTEN THEY HAPPEN AND WHAT TO DO ABOUT THEM
• IUD expulsion• Missed oral contraceptives Call your doctor immediately if the following symptoms and signs of serious adverse effects occur: • A delay in starting a new packet of oral contraceptives • A delay in getting a scheduled contraceptive injection • Cramping or severe pain in your stomach or belly prior to your next normal period, since this can be a warning sign of tubal (ectopic) pregnancy – a serious When it should not be used:
• If you vomit in less than 1 hour after taking the tablet, as you may need to take another dose • If your period is delayed more than 1 week, in case you might be pregnant. • you are allergic to it, or to any of the components of its formulation (for list of components, see the section “what the nonmedicinal ingredients are”) HOW TO STORE IT
What the medicinal ingredient is:
Store Plan B® tablets between 15°C and 30°C (59-86 °F). Protect from high humidity (such as damp storage conditions). What the nonmedicinal ingredients are:
Colloidal silicon dioxide, potato starch, magnesium stearate, talc, corn starch and lactose monohydrate.
REPORTING SUSPECTED SIDE EFFECTS
What dosage forms it comes in:
To monitor drug safety, Health Canada collects The package contains two tablets, each containing 0.75 mg of levonorgestrel. The tablet is white, round, and marked INOR.
information on serious and unexpected effects of drugs. If you suspect you have had a serious or unexpected reactionto this drug you may notify Health Canada by: WARNINGS AND PRECAUTIONS
Serious Warnings and Precautions
• Plan B® provides no protection against HIV/AIDS and other sexually transmitted diseases (STDs), such as syphilis, gonorrhoea, chlamydia, and herpes. If
you are worried about whether you may have been infected with HIV/AIDS, or other sexually transmitted diseases, talk to your health professional about your concerns and ask how you can protect yourself in the future.
• If you do not get your period in the next 21 days after using Plan B®, you should contact your doctor and have a pregnancy test done.
Marketed Health Products Safety and Effectiveness Plan B® is for Emergency Contraceptive Use Only and should not be used on a regular basis. Plan B® provides only short-term protection against pregnancy. Sexual activity that takes place later can still result in pregnancy if no contraceptive is used. You must abstain from sex or use another barrier method of birth control until your next normal period to make sure you do not get pregnant. If you are sexually active and do not wish to become pregnant, you should use a reliable method of contraception on a regular basis. If you want more information about regular contra- ceptives or if you are having trouble using a method, ask your health professional for help in choosing a method that works for you. NOTE: Before contacting Health Canada, you should contact your physician or pharmacist. BEFORE you use Plan B®, talk to your doctor or pharmacist if you have now or have previously had any of the following conditions:
• Unusual vaginal bleeding that has not yet been diagnosed MORE INFORMATION
This document plus the full product monograph, prepared for health professionals can be found by contacting the sponsor, Paladin Labs Inc., at: • You have diabetes• You are using any other medication • You have hypertension (a heart condition) Montreal, Canada H4P 2T4 Last revised: March 2007 INTERACTIONS WITH THIS MEDICATION
Drugs that may interact with Plan B® include: Anticonvulsant drugs (phenytoin, carbamazepine), antibiotics (ampicillin, cotrimoxazole, tetracycline, temafloxacin, clarithromycin), rifampicin, acetaminophen.
Tell your doctor if you have taken Plan B® within 3 days of a Pap test, as it may affect your results. PROPER USE OF THIS MEDICATION
Plan B® can prevent pregnancy if the 2 tablets are taken together within 72 hours (3 days) after a contraceptive accident or unprotected sex (sex without birth
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