OSTEOPOROSIS RISK FACTORS AND TREATMENT OPTIONS FACT SHEET What is osteoporosis? Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures of the hip, spine and wrist. Wolff’s Law (1868) states that bone mass and density will be increased in areas of stress. Conversely
Advantag of ingestion administration way is its easiness even when applied at home. But with their help necessary treatment concentration in blood cannot be always quickly achieve doxycycline online transaction is carried out on anonymity and mutual profit principles, and in addition customers will be positively surprised with quality and speed of service.
Multiple Sclerosis (MS) is a condition that affects Central Nervous System (the
brain and spinal cord). In MS the speed and accuracy of the signals that travel
along the nerves are diminished. The motor and sensory nerves are affected.
Messages that convey information from the outside environment to the brain
are sent through sensory fibres. For example if someone touches something
hot, temperature information travels up a sensory nerve to the brain. Motor
nerves send messages from the brain to muscles; this in turn produces some
sort of movement.
A short and simple description of how the nerve sends information is
necessary to enable some understanding of why information is affected in MS.
Nerve fibres (or axons) connect to other nerve fibres and to other parts of the
body such as the eyes, muscles, skin, heart, stomach and bladder. The neural
impulse (message) travels up or down these sets of axons. Around the axon
is a sheath that has many layers called myelin. This sheath insulates the axon
and its presence helps messages travel with great speed and clarity.
In MS the myelin is affected which decreases the speed and clarity of the
information, this in turn affects the person’s ability to function in some way.
During a MS attack inflammation occurs in the myelin sheath, in random
patches. The random patches are called plaques. The myelin is then
destroyed, and scars are formed where damage has occurred.
Multiple Sclerosis is called multiple because it affects many parts of the brain
and spinal cord. Sclerosis is a Greek word meaning hardened tissue that
interrupts signals travelling.
Cause of MS:
The cause of MS is not known.
The following theories about the cause of MS are as follows:
MS may be due to a virus to which some people have inherited The immune system has reacted in an unusual way to a common virus. There is a virus that lies dormant in the system for many years before The body’s immune system over-reacts and attacks the virus plus the host (in this case the myelin sheath covering the axons). Pattern of MS:
MS is a chronic and progressive.
There are four types of MS.
Relapsing-remitting MS. This is when a person has symptoms of MS that resolve. When the symptoms have resolved, the person is said to be in remission. Each time the person has a relapse, the symptoms will be worse than the previous bout of MS. Primary Progressive MS, where there is a worsening of symptoms since the onset of MS, and there is no full recovery between bouts of MS. Secondary Progressive MS forms of MS have exacerbations and remissions, followed by steady worsening of symptoms. Progressive relapsing MS tends to be progressive from the onset, but
To diagnose MS is very difficult because of the patterns of relapsing and
remissions. Often after the first time a person has MS, it does not reappear for
a long time. Initial attacks may be brief and sometimes mild enough to be
unrecognisable. Other factors that make it difficult to diagnose are that there is
no single test to confirm MS; and individuals have differing symptoms.
Symptoms usually appear between the ages of 20 to 40. Initial diagnosis
seldom occurs for people under 15 years of age or over 50 years of age. More
women are affected than men.
World wide, the incidence of people who have MS is greater in cool climate
zones, therefore people who live closer to the equator are less likely to get
MS. In Australia eg the incidence in Northern Queensland is between 5 and
18 per 100 000, whereas in Tasmania the incidence is closer to 75 per 100
MS is more common in white races.
A person has a greater risk of developing MS if they have a close relative with
MS, than a person without a relative who has MS. One in ten people who
have MS have or will have a relative with MS.
Most people with MS have a near normal life expectancy. Most people have a
few effects, however at its worst, MS will cause a person to find it difficult to
do most tasks including holding objects, speaking and walking.
There are many symptoms that are associated with MS. Someone with MS
will not get all the symptoms. Individuals will have different symptoms to
Motor (movement) symptoms are symptoms that occur due to the muscular
system not working effectively. Some of the problems are: diminished
balance, and unsteadiness upon walking, spasticity (a tightness in the
muscles of the trunk, arms and legs), and they may have “shaky” hands
leading to an inability to manipulate objects. When the muscles around the
mouth move poorly, the person may have difficulty forming their words and
Perceptual difficulties are difficulties with interpreting the external
environment. For example a person might not be able to determine that an
object is hot, cold or sharp.
Problems with sensation may occur and may cause the person a lot of
discomfort. They may experience “pins and needles”, or pain in various parts
of the body.
A person’s cognitive ability such as being able to plan, sequence, solve
problems or concentrate may be affected if the MS affects their brain.
It is not uncommon for vision to be impaired. Double vision may be present, or
there may be an unusual amount of side-to-side movement of the eyes (this is
called nystagmus). If the nerve that goes to the eye is affected pain and loss
of vision from the central part of the eye may result.
Bladder and bowel problems can be part of MS. Bowel problems are usually
in the form of constipation. Bladder problems however, are varied. Feeling an
urgent need to go to the toilet even if the bladder is not full (frequency) is the
first problem. Retention, whereby only a small amount of urine is passed, and
hesitancy-difficulty starting to urinate can occur. Lastly urgency can occur
(there is little warning of needing to go to the toilet). If there is a need to rush
to the toilet, the person’s risk of having a fall is increased.
A general feeling of fatigue is very common. Often a short rest will help to
reduce fatigue. Heat however, increases fatigue and worsens other symptoms
of MS. Heat can be from being in a hot room, or in the sun; or it can be heat
from a raised body temperature.
MS can place pressure on people’s lives in many ways. This can impact on
the person’s feelings, ability to socialise and to fulfil roles they have previously
fulfilled easily. It is unknown when someone will have a relapse of MS and
what affects that relapse will cause, living with this uncertainty is likely to
cause stress. Fatigue may reduce the person’s ability to socialise in the way
they did before being diagnosed with MS. If a person loses their job or
chooses not to work due to having MS, the reduction in finances may reduce
their ability to socialise.
In the family realm, having MS can change interaction with family members.
Physical problems may reduce sexual function; this is likely to change the
nature of the person’s relationship with his/her partner. Fatigue and other
problems may prevent the person from interacting with their children in too
many pursuits, or in too active ways.
Depression is thought to affect 50% of people with MS. Some understanding
of what the person with MS is experiencing may help others to provide
empathic and practical support.
There are a number of medications that are used for treatment of symptoms
of MS. All medications have side effects. The side effects of the most
commonly used medications are as follows:
Diazepam is used to relieve muscle spasms and seizures. The side effects
include: drowsiness, dizziness, tiredness, diarrhoea, upset stomach, changes
in appetite, restlessness, blurred vision, difficult and frequent urination,
changes in sex drive or ability.
Baclofen is a muscle relaxant; it relieves spasms and cramping in muscles.
Side effects include: visual or auditory hallucinations, depression, mood
changes, dizziness, fainting, nausea, muscle weakness, ringing/buzzing in the
ears, confusion and drowsiness.
Dantrium is also used to treat spasticity or muscle spasms. The side effects
include: muscle weakness, drowsiness, fatigue, dizziness, diarrhoea and
Prednisolone is used to produce faster recovery from a relapse of MS. The
most common side effects include: Decreased or blurred vision, frequent
urination, increased and thirst.
NSW MS Societies:
The Multiple Sclerosis Society of NSW, head office, provided the following
NSW head office: Lidcombe:
Gloria McKerrow House
117 Denison Street
Ph: (02) 6281 2921
National Institute of Neurological Disorders and Stroke. 2002. NINDS Multiple
Sclerosis Information Page. Available online: http://www.ninds.nih.gov/health-
National Library of Medicine. 2002. Medline Plus Health Information. Available
National Multiple Sclerosis Society of Australia Ltd. 1989 Multiple Sclerosis
the Mystery Disease. National Multiple Sclerosis Society of Australia,
National Multiple Sclerosis Society of Australia Ltd. 1991. Spasticity and how
it Relates to Multiple Sclerosis. National Multiple Sclerosis Society of
National Multiple Sclerosis Society of Australia Ltd. What everyone should
know about Multiple Sclerosis. National Multiple Sclerosis Society of Australia,
National Multiple Sclerosis Society. 1990. Things I Wish Someone Had Told
Me: Practical Thoughts for People Newly Diagnosed with Multiple Sclerosis.
National Multiple Sclerosis Society, New York.
National Multiple Sclerosis Society of Australia Ltd. 1990. Living With Multiple
Sclerosis: A book for the Newly Diagnosed. National Multiple Sclerosis
Society of Australia, Melbourne.
Neurological Resource Centre 1998Neurological Conditions Information
Manual. Neurological Resource Centre of SA Inc Unley, South Australia.
Multiple Sclerosis – Neurology Channel 2002 Available online: www.neurologychannel.com Issue: The person may feel fatigued.
Do not think reduced participation is laziness, it is or they may need a rest Provide activities to suit the person’s energy level. during the activity. Break down activities to allow participation in parts of the activity or resumption of the activity after the person has had a break. Provide a quiet room away from activity where the person can go for some time out/ a rest before they become tired. Offer help for shopping, meal preparation etc… to help the person have more energy to participate in more enjoyable activities. Provide activities that are not always active, as sometimes participation in quiet activities would be possible, whereas activities that require too much active participation may mean the person cannot join in. If activities are outdoors, ensure it is not too hot and make sure there is plenty of shade. Make sure room temperature is not too hot, because heat increases fatigue. Issue: The person experiences urinary urgency.
The person needs to be Provide a unisex accessible toilet, make sure that able access the toilet the path to the toilet is clear and well sign posted. Make sure indoor and outdoor activities are near toilet facilities. For example if you go to a local park, ensure that there is a toilet facility (that is open) at the park. Accept that people may need come and go from the group to fit in with their toilet needs. Issue: The person has perceptual difficulties such as knowing whether
something is hot or sharp.
Make sure that if you have heaters on (particularly ones under the pews) that the person knows that the heating is on. Do not turn up the heating too high. If working in the kitchen, an activity like buttering bread would be easier, safer and would require less energy than cutting carrots etc. Offer to carry hot items eg tea/coffee for the person, so the person doesn’t risk burning him/herself by spilling it whilst walking. Issue: The person is unsteady walking or has poor standing balance.
Ensure the paths around the church and hall are increased risk of falling, smooth. and may find walking on uneven surfaces Ensure paths are wide enough to accommodate walking aids. Make sure paths are not mossy or slippery. Provide rails on both sides of stairs. If children are present, remind them not to run around where there are groups of people. Ensure they do not run across the person with MS. Explain to the children that the person is likely to be put off balance, and even may fall if the children bump into them whilst running. Allow time to move from one space to the other as hurrying will increase the risk of falls. Walking on grass and other uneven surfaces are more difficult than paved surfaces so check the area is not too uneven if planning outdoor activities. Issue: The person may not be able to concentrate or think as clearly as
they did before they had MS.
Reduce the amount of people talking at any one Decisions made and activities to be done are best to be written down. Give the person time to complete tasks, give them a choice of doing tasks themselves if this enables them to think things through without the pressure of others. Ensure that activities are within their concentration span, or that they can resume the activity at another time, if their concentration has dwindled. Issue: The person may have visual difficulties such as nystagmus or
Provide large print copies of handouts, Bibles and The person may choose to cover one eye to stop vision from being double. Reading may be difficult. Provide tapes if necessary. Offer the person to do other activities, eg ask them to be the offering steward, rather than the person who does the readings at church. Operating machinery and driving is not recommended if they are currently experiencing visual problems. Activities that use heat and cutting, such as cooking or woodwork are likely to be dangerous if the person’s vision is affected. Provide other options for tasks. If the person realistically feels that these activities are within their capabilities, provide supervision and/or help. Do not do too many activities that require close vision.
LA MEMORIA DI SAN BARTOLOMEOquartiere di Trentoprogetto di Trento ASA – associazione di cultura fotograficain col aborazione con gli utenti del gruppo Facebook “San Bartolomeo, ricordi innocenti non solo reati”.e nar tra le Palafite sul pra' dela roza a lezer Voltaire o Carlo Marx . enventar che la rivoluzion la doveva partir da lì, magari dagli operai de le fabriche de via Fermi … tut