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r. med. Ovidiu Alin Stirban
Publication list
Stirban A, Negrean M, Stratmann B, Gawlowski T, Horstmann T, Gotting C, Kleesiek
K, Muel er-Roesel M, Koschinsky T, Uribarri J, Vlassara H, Tschoepe D: Benfotiamine
prevents macro- and microvascular endothelial dysfunction and oxidative stress fol owing a
meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes
Care
2006, 29:2064-2071. (Impact factor 7.5)
Stirban A, Negrean M. Endotheldysfunktion: Verbindung von Insulinresistenz,
Diabetes und Atherosklerose? Diabetes, Stoffwechsel und Herz, 2006, 2: 41-52.
Negrean M*, Stirban A*, Stratmann B, Gawlowski T, Horstmann T, Götting C,
Kleesiek K, Mueller-Roesel M, Koschinsky T, Uribarri J, Vlassara H, Tschoepe D. Effects of
low- and high-AGE (Advanced Glycation Endproducts) meals on macro- and microvascular
endothelial function and oxidative stress in patients with type 2 diabetes mel itus. The
American Journal of Clinical Nutrition,
2007 May;85:1236-43,(*shared 1st place).
Wound therapy with
autologous bone marrow stem cells in diabetic patients with ischaemia-induced tissue ulcers
affecting the lower limbs. Int J Clin Pract. 2007;61:690-692.
Stirban A, Negrean M, Stratmann B, Götting C, Salomon J, Kleesiek K, Tschoepe D.
Adiponectin decreases postprandial y fol owing a heat processed meal in people with type 2
diabetes mellitus - an effect prevented by benfotiamine and cooking method. Diabetes Care.
2007 Oct;30(10):2514-6. (Impact factor 7.5)
Stirban A, Petrule S, Negrean M, Koschinsky T, Tschoepe D. Skin autofluorescence
increases postprandial y in human subjects. Diabetes Technol Ther. 2008 Jun;10(3):200-5.
Stirban A, Tschoepe D. Should we be more aggressive in the therapy against
cardiovascular risk factors? Should we prescribe statin and aspirin for every diabetic
patient? Is it time for polypill? Diabetes Care. 2008 Feb;31 Suppl 2:S226-8. (Impact
factor 7.5)

Stirban A, Tschoepe D. Cardiovascular complications in diabetes -Targets and
interventions - Diabetes Care. 2008 Feb;31 Suppl 2:S215-21. Review. (Impact
factor 7.5)

Uribarri J, Stirban A, Sander D, Cai W, Negrean M, Buenting CE, Koschinsky T,
Vlassara H: Single oral chal enge by advanced glycation end products acutely impairs
endothelial function in diabetic and nondiabetic subjects. Diabetes Care. 2007
Oct;30(10):2579-82. (Impact factor 7.5)
Gawlowski T, Stratmann B, Stirban A, Negrean M, Tschoepe D: AGEs and
methylglyoxal induce apoptosis and expression of Mac-1 on neutrophils resulting in
platelet-neutrophil aggregation. Thromb Res. 2007;121(1):117-26.
Stirban A, Negrean A, Götting A, Gawlowski T, Stratmann B, Kleesiek K, Tschoepe D.
Dietary advanced glycation end products: in vivo effects on endothelial function and
adipokines. Ann N Y Acad Sci. 2008 Apr;1126:276-9.
Stirban A, Rösen P, Tschoepe D. Complications of type 1 diabetes – new molecular
findings. Mt Sinai J Med. 2008 Aug;75(4):328-51
Leptin Decreases Postprandial y in People
with Type 2 Diabetes, an Effect Reduced by the Cooking Method. Horm Metab Res.
2008 Sep 15; 40: 896-900.
Stirban A, Laude D, Elghozi JL, Sander D, Agelink M, Hilz MJ, Ziegler D. Effects of
Sildenafil on Flow Mediated Dilatation and Cardiovascular Autonomic Nerve Function
in Type 2 Diabetic Patients. Diabetes Metabolism Research and Reviews. 2009
Feb;25(2):136-43.
Stirban A. Zycose: a new drug for the treatment of diabetes complications ? Drugs of
Today (Invited review), Drugs Today (Barc). 2008 Oct;44(10):783-96.
Stirban A, Tschoepe D, Stratmann B. Shifting the disease management paradigm
from glucose. Diabetes Care. 2009 Nov;32 Suppl 2:S349-52.
Stirban A, Lentrodt S, Nandrean S, Pop A, Tschoepe D, Scherbaum WA. Functional
Changes in Microcirculation During Hyperbaric and Normobaric Oxygen Therapy.
Hyperbaric Undersea Medicine. Undersea Hyperb Med. 2009 Sep-Oct;36(5):381-90
Stirban A, Nandrean S, Götting C, Tamler R, Pop A, Negrean M, Gawlowski T,
Stratmann B, Tschoepe D. Effects of Prescription Omega-3-Acid Ethyl Ester on Macro- and
Microvascular Function in Subjects with Type 2 Diabetes Mel itus. American Journal of
Clinical Nutrition.
Am J Clin Nutr. 2010 Mar;91(3):808-13. Epub 2010 Jan 13.
Stirban A. Nahrungs Advanced Glycation End Products. Diabetes, Stoffwechsel
und Herz (Diabetes, Metabolism, and the Heart). 2009; 18:290-295.
Stirban A. Die Bedeutung von AGEs und ROS bei Atherosklerose. Herz
Borza N, Stirban A. Sport bei Herzinfarkt. Diabetes aktuel 2/2010
Stirban A. Effects of ω-3 fatty acids on vascular function in subjects with type 2
Diabetes mel itus. AgroFood industry hi-tech - November/December 2010; 21: 31-33.
Stirban A, Tamler R, Veresiu A. Effects of phosphodiesterase type 5 inhibitors on
endothelial function and cardiovascular autonomic nerve function in men. Journal of Men’s
Health
. 2011; 8(2):109–118.
Stirban A. Pathogenetische Rol e der Advanced Glycation End Products (AGE).
Diabetes Stoffwechsel und Herz. 2011;20(3):191-192.
Stirban A, Veresiu IA, Tamler R. Effects of Omega-3 Ethyl Esters on Macro- and Microvascular Function in Subjects with Type 2 Diabetes Mel itus. Treatment Strategies
Diabetes
. 2011: 197-202.
26. L Barkai, I Gurieva, A Stirban, S Tesfaye, L Czupryniak, BN Mankovsky, V Spallone,
IA Veresiu, O Schnel , P Kempler. Microvascular complications in children and adolescents with type 1 diabetes. Diabetes, Stoffwechsel und Herz. 2012;21:309-315 .
27. DM Cheța, E Rusu, A Stirban, C Constantin. HbA1c: Importance for Diagnosis and
Treatment. Diabetes, Stoffwechsel und Herz. In press.
28. A. Stirban, S. Del weg. Neue Methoden zur Diagnose mikrovaskulärer Komplikationen. Diabetes Congress-Report. 2012;5:22-25.
Stirban A, S Nandrean, S Kirana, C Götting, I A Veresiu, D Tschoepe.
Benfotiamine Counteracts Smoking Induced Vascular Dysfunction in Healthy Smokers. International Journal of Vascular Medicine. 2012 (open access Journal).
Stirban A, P Kotsi, K Franke, U Strijowski, W Cai, C Götting, D Tschoepe. Acute
Macrovascular Dysfunction in Patients with Type 2 Diabetes Mel itus Induced by Ingestion of Advanced Glycated Betalactoglobulins. Diabetes Care. 2013
May;36(5):1278-82 (2012 Dec [Epub ahead of print]).
Várkonyi T, Putz Z, Keresztes K, Martos T, Lengyel C, Stirban A, Jermendy G,
Kempler P. Current options and perspectives in the treatment of diabetic neuropathy. Curr Pharm Des. 2012 Dec 26. [Epub ahead of print] Stirban A. Therapie der diabetischen Neuropathie. Diabetes Congress-Report
Stirban A. Im Fokus: mikrovaskuläre Folgeerkrankungen des Diabetes mel itus.
Ärztliches Journal Reise & Medizin. 2/2013
Stirban A, Pop A, Tschoepe D. A Randomized, Double-Blind, Cross-Over,
Placebo-Controlled Trial to Investigate the Effects of a 6 Weeks Benfotiamine Treatment on Postprandial Vascular Function and Variables of Autonomic Nerve Function in Type 2 Diabetes Mel itus. Diabetic Medicine (in press).
Stirban A, Pop A, Fischer A, Heckermann S, Tschoepe D. Variability of Skin
Autofluorescence Measurement Over 6 and 12 Weeks and the Influence of Benfotiamine Treatment. Diabetes Technology and Therapeutics (in press).
Stirban A. Noninvasive Skin Fluorescence Spectroscopy for Diabetes
Screening. Journal of Diabetes Science and Technology (in press).
Book chapters
Pschyrembel Wörterbuch Diabetologie. Erste Auflage. Herausgeber W.A.
Pschyrembel Wörterbuch Diabetologie. Zweite Auflage. Herausgeber W.A.
Modern therapies for diabetes mellitus. Editor: Nicolae Hancu. Publishing house
of the Iuliu Hatieganu University, Cluj-Napoca, Romania 2008.
Complications of Diabetes mellitus: Pathophysiology and Pathogenetically-based
Treatment options. Editors: Paul Thornal ey, Peter Kempler. Georg Thieme Verlag 2009. Handbook of Vitamin C Research: Daily Requirements, Dietary Sources and
Adverse Effects
. Hubert Kucharski and Julek Zajac. Nova Publishers, USA, 2009 ISBN:978-1-60741-874-0
Functional Disturbaces in the Vascular Endothelium and Advanced Glycation
End Products: the role of Benfotiamine. In Rett et al. Better Chances for Nerves and
Vessels, Thieme Verlag 2011, ISBN: 9783131624512.
Reviewer for
“Experimental and Clinical Endocrinology and Diabetes” “Molecular Nutrition and Food Research“ “Diabetes, Technology and Therapeutics”

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lation in its western-most quarterrelies on groundwater for drink-ing water. In addition, highly con-sumptive uses, such as agriculturalirrigation are increasing.2From 1985 through 1988, whenprecipitation statewide was 75percent of normal and streamflowhalf of normal, serious declines inwater quality occurred leading toemergency measures to allocateand conserve, including local banson nonessen

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PROBING DARK ENERGY WITH SUPERNOVA SEARCHES CENTRA – Centro Multidisciplinar de Astrofísica, Instituto Superior Técnico, Lisbon Abstract. Four years ago, two teams presented independent analyzes coming from photometry of type Ia supernovae at various distances. The results presented back then shook-up the scientific community: the universe is accelerating with a positive repulsive flu

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