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Microsoft word - dieter zimmer publication list 10-2013.doc

Dr. Dieter Zimmer, Publication List, 10/2013 LIST OF PUBLICATIONS AND PRESENTATIONS
Papers, until 1989 in the former GDR (East Germany)
Papers on the Surface Enhanced Raman Scattering (SERS) 1) D. Zimmer, K. Klostermann, Z. Chemie, 24 (1984) 302 2) D. Zimmer, K. Klostermann, Z. Chemie, 24 (1984) 450 3) D. Zimmer, Teubner Texte zur Physik, 1986 Papers on structure elucidation in coal derived liquids by tandem mass spectrometry: 4) J. Stach, D. Zimmer, R. Herzschuh: Konsekutive Fragmentierungsreaktionen derivatisierter Hydroxy-Aromaten, Z. Chemie, 29 (1989) 178-179 5) J. Stach, D. Zimmer, M. Möder, R. Herzschuh: Determination of hydroxyaromatic compounds in complex mixtures by tandem mass spectrometry, Org. Mass Spectrom. 24 (1989) 946-952, 6) M. Möder, D. Zimmer, J. Stach, R. Herzschuh: GC/MS and MS/MS investigations of derivatized hydroxyaromatic compounds from coal derived liquids, Fuel, 68 (1989) 1422-1428 Papers, since 1990
7) D. Zimmer, V. Muschalek: Enantioselective assay for the determination of nisoldipine in dog, rat and mouse plasma by chiral microbore high-performance liquid chromatography combined with gas chromatography-mass spectrometry, J. Chromatogr. A, 666 (1994) 241-248 8) D. Zimmer: Turbulent Flow Chromatographie, CLB Chemie in Labor und Biotechnik, 9) D. Zimmer, V. Pickard, W. Czembor, C. Müller: Comparison of turbulent-flow chromatography with automated solid phase extraction in 96 well plates and liquid-liquid extraction used as plasma sample preparation techniques for liquid chromatography-tandem mass spectrometry, J. Chromatogr. A, 854 (1999) 23-35 10) N. Wenkel, D. Zimmer: Analyse im Eiltempo – Automatisierte Online-Probenvorbereitung und Analyse pharmazeutischer Wirkstoffe, Pharma-Process, 2-1999, 34-35 11) D. Zimmer, V. Pickard, W. Czembor, C. Müller: Turbulent Flow Chromatography combined with tandem Mass Spectrometry for directly injecting raw plasma samples derived from pharmacokinetic studies, Chromatogr. Suppl. 52 (2000) S-26-27 12) D. Zimmer, V. Muschalek, C. Müller: Determination of the metrifonate enantiomers in blood and brain samples using liquid chromatography on a chiral stationary phase coupled to tandem mass spectrometry, Rapid Commun. Mass Spectrom. 14 (2000) 1425-1432 13) R. Heinig, D. Zimmer, S. Yeh, G.J. Krol: Development, validation and application of assays to quantify metrifonate and 2,2-dichlorovinyl dimethylphosphate in human body fluids, J. Chromatogr. B, 741 (2000) 257-269 14) D. Zimmer: Introduction to quantitative LC/MS(MS), Chromatographia, Supplement 57 15) J. Schuhmacher, D. Zimmer, F. Tesche, V. Pickard: Matrix effects during analytics of plasma samples by electrospray and atmospheric pressure chemical ionization tandem mass spectrometry: occurence and elimination, Rapid Commun. Mass Spectrom., 17 (2003) 1950-1957 Dr. Dieter Zimmer, Publication List, 10/2013 Papers, since 1990 (contd.)
16) Th. Schwarz, B. Beckermann, K. Buehner, F. Mauler, J. Schuhmacher, D. Seidel, W. Steinke, C. Weinz, D. Zimmer: Pharmacokinetics of Repinotan in Healthy and Brain Injured Animals, Biopharm. Drug Dispos. 26 (2005) 259-268 17) D. Zimmer, C. Philipowski, B. Posner, A. Gnielka and M. Dorff: Determination of deltamethrin residues in plant materials by liquid chromatography/tandem mass spectrometry with electrospray ionization, J. AOAC International 89 (2006) 786-796 18) R. Sur, D. Zimmer: HPLC-MS/MS in der Rückstandsanalytik von Pflanzenschutzmitteln, UWSF – Z. Umweltchem. Ökotox. 18 (2006) 21-26 19) O. Heudi, S. Barteau, D. Zimmer, J. Schmidt, K. Bill, N. Lehmann, C. Bauer, O. Kretz: Towards absolute quantification of therapeutic monoclonal antibodies in serum by LC-MS/MS using stable isotope-labeled antibody internal standard and protein cleavage isotope dilution mass spectrometry, Anal. Chem. 2008, 80(11), p. 4200 – 4207 20) D. Zimmer, S. Hassler, B. Betschart, S. Sack, C. Fankhauser, M. Loppacher: Internal Standard Application to Dried Blood Spots by Spraying – Investigation of the Internal Standard Distribution, Bioanalysis (2013) 5(6), 711-719 21) K. Heinig, E. Zwanziger, D. Zimmer: What are the challenges of stability investigations and sample stabilization in regulated bioanalysis?, Bioanalysis (2013) 5(15), 1811–1814 22) D. Zimmer: Bioanalytical outsourcing – the two sides of the medal., Bioanalysis (2013) 23) Ask the Experts: Outsourcing in a bioanalytical laboratory, Bioanalysis (2013) 5(20), 24) D. Zimmer: Bioanalytical Method Validation - the draft novel FDA guidance, chromatographic methods and ISR: notable differences to the current one and comparison with the EMA BMV guideline, Bioanalysis (2014) 6(1), 13-19 Coauthor of papers as member of EBF topic teams, GBC harmonization teams and GCC: 25) P. Timmerman, S. White, Z. Cobb et al.: Updates from the EBF DBS–micro-sampling consortium, Bioanalysis (2012) 4(16), 1969-1970 26) M. Boterman, M. Doig, M. Breda et al.:, Whitepaper: Recommendations on the
interpretation of the new EMA guideline on bioanalytical method validation by Global CRO Council for Bioanalysis (GCC), Bioanalysis (2012) 4(6), 651–660 27) T. Sangster, J. Maltas, P. Struwe et al.: Recommendations on ISR in multi analyte assays, QA/bioanalytical consultants and GCP by Global CRO Council for Bioanalysis (GCC), Bioanalysis (2012) 4(14), 1723-1730 28) S. Lowes, M. Boterman, M. Doig et al.: Recommendations on bioanalytical method stability implications of co-administered and co-formulated drugs by Global CRO Council for Bioanalysis (GCC), Bioanalysis (2012) 4(17), 2117-2126 Dr. Dieter Zimmer, Publication List, 10/2013 Scientific Posters
1) – 5) Posters on Surface Enhanced Raman Scattering (SERS) at the annual conference „Chemiedozententagung“, GDR, 1984 to 1988 6) D. Zimmer, V. Pickard, W. Czembor, C. Müller: Comparison of turbulent-flow chromatography with automated solid phase extraction in 96 well plates and liquid-liquid extraction used as plasma sample preparation techniques for liquid chromatography-tandem mass spectrometry, 47th ASMS-Conference, Dallas, TX, June 1999 7) D. Zimmer, V. Pickard, W. Czembor, C. Müller: Turbulent flow chromatography/tandem mass spectrometry used for the direct injection of crude plasma samples obtained from pharmacokinetic studies, 48th ASMS-Conference, Long Beach, CF, June 2000 8) D. Zimmer and C. Müller: Determination of the novel PDE 5 inhibitor vardenafil and its main metabolite M-1 by reversed-phase-LC-MS/MS and turbulent flow chromatography-MS/MS, 50th ASMS-Conference, Orlando, FL, June 2002 9) D. Zimmer and W. Czembor: Turbulent Flow Chromatography with Cyclone / Chromolith column pair at high flow directly (without split) run into TuboIonspray MS/MS,16th Int. MS Conference (IMSC), Edinburgh, Scotland, Sept. 2003 10) D. Zimmer, C. Philipowski, B. Posner, A. Gnielka and M. Dorff: A new method for the determination of deltamethrin in plants using LC/MS/MS, European Pesticide Residue Workshop (EPRW), Stockholm, June 2004 11) E. Schmidt, M. Preu, R. Sur, D. Zimmer: Evaluation of Losses During Cryogenic Sample Homogenization With Liquid Nitrogen and Dry Ice, European Pesticide Residue Workshop (EPRW), Corfu, June 2006 12) C. Bauer, J. Schmidt, K. Bill, D. Zimmer, O. Heudi, S. Barteau: Stable isotope labeled monoclonal antibodies: tool antibodies, Novartis Pharma TRD Scientific Day, 09. Nov. 2007 13) A. Lesur1; E. Varesio1; N. Oudry1; O. Heudi2; D.Zimmer2; St. Beck2; G.Hopfgartner1, 1Life Sciences Mass Spectrometry, Geneva University; 2Novartis, Basel: Quantitative analysis of a therapeutic protein in human plasma by LC-MS/MS using accelerated digestion, Poster no. 963 at 56th ASMS Conference, Denver, June 2008 14) D. Zimmer, O. Heudi, M. Stöckli, R. Falchetto, A. Schweitzer, Novartis Pharma AG: Quantification of Drugs in Tissues by MALDI-QqQ Mass Spectrometry, NIBR/TS Science Day, Oct 01/02, 2008 15) S. Weber1, B. Betschart1, S. Sack1, M. Loppacher2, C. Fankhauser2, T. Zimmermann1, D. Zimmer1, 1 Harlan Laboratories Ltd., Itingen, CH; 2 CAMAG, Muttenz, CH: Evaluation of the semi-automated DBS-MS Interface (CAMAG) for On-line Extraction DBS (OLE-DBS), 3rd EBF Open Symposium, Barcelona, Dec. 2010 http://www.camag.com/en/dbs/what_is_dried_blood_spot_sampling.cfm 16) D. Zimmer1, S. Hassler1, B. Betschart1, S. Sack1, C. Fankhauser2, M. Loppacher2 1 Harlan Laboratories Ltd., Itingen, CH; 2 CAMAG, Muttenz, CH: Internal Standard (IS) Application to Dried Blood Spots (DBS) - Evaluation of a Novel Automated Application System, 59th ASMS Conference, Denver, CO, USA, Jun. 2011 http://www.camag.com/en/dbs/what_is_dried_blood_spot_sampling.cfm 17) D. Zimmer1, S. Hassler1, B. Betschart1, S. Sack1, C. Fankhauser2, M. Loppacher2 1 Harlan Laboratories Ltd., Itingen, CH; 2 CAMAG, Muttenz, CH: Internal Standard (IS) Application to Dried Blood Spots by Spraying – Investigation of the IS distribution, 4th EBF Open Symposium, Barcelona, Nov. 2011 http://www.camag.com/en/dbs/what_is_dried_blood_spot_sampling.cfm Dr. Dieter Zimmer, Publication List, 10/2013 Oral Presentations
Presentations on the application of LC/MS/MS in Bioanalytics and Pharmacokinetics - Seminar, University Düsseldorf, Feb. 1994 European Pharma-Symposium of Perkin-Elmer on Modern Separation Techniques in Pharmacy and Biopharmacy (original title „Moderne Trenntechnik in der Pharmazie und Biopharmazie“), Berlin and Frankfurt, Feb. 1995 Perkin-Elmer vendor seminar for Bayer AG, Wuppertal, Dec. 1996 Bio-Mass Spectrometry Club, Cancer Research Center (DKFZ), Heidelberg, 1998 Organizer and chair of biannual LC/MS conferences (www.lc-ms.de) since 1996, entitled: “LC/MS Diskussionstreffen – Aktuelle Probleme in der Quantifizierung mit LC-API-MS(/MS)”, Frankfurt, Wuppertal, Presentations on various topics regarding LC/MS, bioanalytics and residue analysis. D. Zimmer: Quantitation by high throughput LC/MS/MS in pharmacokinetics with main focus on automated on-line solid phase extraction, Perkin-Elmer European Seminar „Accelerating Drug Discovery“, Heidelberg, Feb. 1997 D. Zimmer, C. Müller, V. Pickard: Determination of azlocillin and two of its metabolites by direct injection of crude plasma onto two alternating ADS columns and on-line quantitation by LC-tandem mass spectrometry: Perkin-Elmer LC/MS-users meeting, Montreux, Nov. 1996 Annual Conference of the German Society of Mass Spectrometry, Konstanz, 1997 D. Zimmer: Comparison of Turbulent Flow Chromatography, automated SPE in 96 well plates and liquid/liquid extraction used as sample preparation techniques for LC/MS/MS, 15th Montreux Symposium on LC/MS, Montreux, Nov. 1998 D. Zimmer, V. Pickard, W. Czembor, C. Müller: TFC combined with API/Tandem Mass Spectrometry: A novel technique for the direct injection of crude plasma samples obtained in pharmacokinetics, Analytica Conference 2000, Munich D. Zimmer, V. Muschalek, C. Müller: Determination of the metrifonate enantiomers in blood and brain samples using liquid chromatography on a chiral stationary phase and turboionspray/MS/MS, 17th Montreux Symposium on LC/MS, Montreux, Nov. 2000 D. Zimmer, W. Czembor, C. Müller and C. Nieland: Comparison of Turbulent Flow Chromatography, Protein Precipitation and SPE in Bioanalysis: Applied Biosystems LC/MS-Meeting, Leipzig, May 2001 Seminar on Turbulent Flow Separations in LC/MS, TNO Pharma, Zeist, NL, Oct. 2001 D. Zimmer: Tutorial - Introduction to quantitative LC/MS(MS), International Symposium on Chromatography, Leipzig, Sept. 2002 D. Zimmer: Sensitive Quantitation in Pharmacokinetics with the API 4000 and Turbulent Flow Chromatography, LC/MS-vendor symposium, Applied Biosystems, Cologne, Sept. 2002 D. Zimmer, C. Müller and T. Blenkers: Vergleichende Quantifizierung mit Ion Trap MS und Triple Quadrupol MS in PK, Science Day at Axel Semrau GmbH, Sprockhövel, Dec. 2003 D. Zimmer: Current Problems in Quantitative LC-API/MS(MS), LC/MS workshop, DGMS Conference, Leipzig, Mar. 2004 D. Zimmer: Applications of Turbulent Chromatography / MS/MS in Pharmacokinetics, University Twente, Section Chemical Analysis, Enschede, Netherlands, Mar. 2004 Dr. Dieter Zimmer, Publication List, 10/2013 Oral Presentations (contd.)
D. Zimmer, P. Billian, R. Schöning: The strengths of LC-MS/MS in Residue Analysis, 4th Int. Symp. of Pesticides in Food and the Environment in Mediterranean Countries and MGPR Annual Meeting 2005, Aydin, Turkey, Sept. 2005 D. Zimmer, O. Heudi, S. Barteau: Absolute Quantitation of Monoclonal Antibodies by LC/MS, Novartis Pharma AG, Basel, Early Development Science Day, Oct. 2007 D. Zimmer: LC/MS in the Drug Development Workflow - From a DMPK Point of View, ThermoFisher DMPK Training, Basel, Nov. 2007 D. Zimmer: Quantitation in Tissues, German-Swiss Bioanalytical Forum, Basel, Apr. 2008 D. Zimmer on behalf of EBF: Survey on Metabolite Quantitation, 1st EBF Open Symposium, Barcelona, Dec. 2008 D. Zimmer: Training Seminar for Swiss BioAnalytics AG, three presentations: EBF Views on Bioanalytical Method Validation, Quantitation in Tissues and Absolute Quantitation of Monoclonal Antibodies, Birsfelden, Mar. 2009 D. Zimmer: Dried Blood Spots – A Revolution like LC-API-MS 20 years ago?, 2nd EBF Open Symposium, Barcelona, Dec. 2009 Organizer of workshop “Absolute Quantitation of Proteins – Where Are We Today?” at the “8th LC/MS Diskussionstreffen”, Wuppertal, 19/20. Apr. 2010, presentation on different types of internal standards. http://www.lc-ms.de/information.html D. Zimmer on behalf of the EBF Topic Team “Dried Blood Spots (DBS): Internal Standard use with DBS”, 4th EBF Open Symposium, Barcelona, Nov. 2011 D. Zimmer: Dried Blood Spots – Convenient Method to Collect, Store and Analyze Biological Samples, BioValley Stammtisch „Biobanking“, Actelion, Allschwil, Nov. 2011 D. Zimmer on behalf of GBC A2 team: Tiered Approaches to Method Validation, DMDG Leaders Meeting, Actelion, Allschwil, May 2012 Organizer of workshop “Automatization of DBS Analysis”, presentation: Internal standard application to Dried Blood Spots – evaluation of a novel automated application system from CAMAG, Fachhochschule Nordwestschweiz, Basel, Sept. 2011 http://www.lc-ms.de/pdf/PDF2012/Invitation_DBS_workshop_06.09.11_final.pdf Organizer of a regulatory bioanalysis workshop at the “9th LC/MS Diskussionstreffen”, Wuppertal, 17/18. Sept. 2012, three presentations on the EMA BMV guideline http://www.lc-ms.de/information.html

Source: http://www.zbam.eu/resources/Dieter+Zimmer+Publication+List+10-2013.pdf

Care for and support the patient before transplant surgery

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Microsoft word - newsletter_pain_and_inflammation2.doc

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