G:\msds\us22105a.wpd

Material Safety Data Sheet
Revision: 10/17/2005
Hazard information is provided for compliance with both the UK Chemicals(Hazard Information and Packaging) (CHIP) Regulations and the US HazardCommunication Standard (HCS) IDENTIFICATION OF THE
SUBSTANCE/PREPARATION
AND COMPANY
Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000
Chemtrec (800) 424-9300
Please visit our website at www.usbweb.com for contact information on USB
Outside USA & Canada 703 527 3887
product distributors within your area.
COMPOSITION/
HAZARDOUS COMPONENTS
CHIP R & S Phrases
R:63 Possible risk of harm tothe unborn child.
R:36/37/38 Irritating to eyes,respiratory system and skin.
R:42/43 May causesensitization by inhalation andskin contact.
S:22 Do not breathe dust.
S:24/25 Avoid contact withskin and eyes.
S:36/37 Wear suitableprotective clothing and gloves.
HAZARDS IDENTIFICATION
CHIP
Harmful
HCS
Irritant
FIRST-AID MEASURES
EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists. SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and wash before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate medical attention. INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give anything by mouth to an unconscious person. FIRE-FIGHTING INFORMATION
Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved selfcontained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. Emits toxic fumesunder fire conditions.
Flash Point = No data available.
ACCIDENTAL RELEASE MEASURES
Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and NIOSH-approved respirator. Collect in a manner that does not create dust and place in a suitable waste container. Avoidcontact of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE
Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and NIOSH-approved respirator. Avoid contact of material with skin or eyes. Light, moisture and air sensitive. Protect fromlight. Store ambient away from incompatible materials.
PERSONAL PROTECTION
Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection. Userespiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of materialwith skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust, vapors or mists.
Access to a safety shower and eye-wash.
MSDS information may be continued on back of page.
PHYSICAL AND CHEMICAL
Appearance: Yellow crystalline powder Boiling Point: No data available PROPERTIES
Vapor Pressure: No data available Vapor Density: No data availableSolubility (Water): Soluble Specific Gravity: No data available Percent Volatile: No data available Evaporation Rate: No data availableChemical Formula: C22-H24-N2-O8AHCl Melting Point: 220-223°C STABILITY AND REACTIVITY
Product is stable. Light, moisture and air sensitive. May discolor on exposure to light. Protect from light. Hazardousdecomposition products include hydrogen chloride gas and oxides of nitrogen and carbon. Incompatible with strongoxidizing agents. Hazardous polymerization will not occur.
TOXICOLOGICAL INFORMATION
EFFECTS OF OVEREXPOSURE:EYES: Contact may cause irritation.
SKIN: Contact may cause irritation, dermatitis and hypersensitive individuals may experience an allergic reaction.
INHALATION: May cause irritation to mucous membranes and upper respiratory tract. Hypersensitive individualsmay experience an allergic reaction. INGESTION: Chronic ingestion or excessive dosage may cause tooth discoloration, gastrointestinal irritation, blooddisorders, liver and kidney damage. May cause allergic reactions in hypersensitive individuals. Has causedteratogenic effects in laboratory animals.
TARGET ORGAN(S): Kidneys, Liver, Teeth and Bones.
ADDITIONAL INFORMATION:Possible risk of congenital malformation in the fetus. Laboratory experiments have resulted in mutagenic effects.
May be harmful by inhalation, ingestion or skin absorption. May cause phototoxic reactions. Prolonged or repeatedexposure may cause allergic reactions in certain sensitive individuals (sensitization).
Reproductive effects, mutation and toxicity data listed in RTECS under QI9100000.
Only select RTECS information is provided here. Please see actual RTECS entry for complete information.
Oral Rat LD50 = 6443 mg/kg (1971). Details of toxic effects not reported other than lethal dose value.
Reproductive: Effects on embryo or fetus included fetotoxicity (except death, e.g. stunted fetus) (1972), fetal death (1972) and extra-embryonic structures (e.g., placenta, umbilical cord) (1965).
Specific developmental abnormalities - musculoskeletal system (1972), endocrine system (1984), blood and lymphatic systems (including spleen and marrow), immune and reticuloendothelial system (1984) and urogenital system (1967).
Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) (1972) and abortion (1971).
Maternal effects - uterus, cervix, vagina (1984).
Carcinogenic data: NCI Carcinogenesis Studies (feed): no evidence: mouse, rat. Definition(s): RTECS = Registry of Toxic Effects of Chemical Substances.
NCI = National Cancer Institute.
ECOLOGICAL INFORMATION
DISPOSAL CONSIDERATIONS
Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION
US DOT / IATA: No applicable information.
REGULATORY INFORMATION
RCRA - No applicable information.
SARA 302 - This material does not have an RQ or TPQ.
SARA 313 - This material contains Tetracycline Hydrochloride (CAS# 64-75-5, 100%) which is subject to thereporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
SARA 311/312 - chronic.
EPA TSCA Section 8(b) - Chemical Inventory.
Exposure Limits - Not established.
California Proposition 65 - This product is or contains chemical(s) known to the state of California to cause developmental toxicity.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of theinformation contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheetmust be determined by the user to be in accordance with appropriate applicable regulations.

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