Microsoft word - c10.2.3 nuclear medicine and bmd june 2008.doc
Nuclear Medicine, PET and Bone Densitometry CURRENT MAJOR USES INDICATIONS PREPARATION
Arthritis Musculoskeletal pain Fractures
Bone Scan
Nil (patients are requested to bring all available x-rays,
Fast minimum 6 hours, although water is permitted Cease Caffeine (tea, coffee, chocolate, cola etc) 24 hours
Myocardial Perfusion
Wear comfortable clothing (including appropriate footwear
Scan (Sestamibi)
See below for details regarding preparation for type of
stress test preparation (persantin, exercise, dobutamine)
Some medications listed below are required to be
withdrawn, if this is not acceptable to the patient or
referring doctor, please contact department
Diabetic patients, please contact department
Cease Theophylline containing medications (e.g.
Theodur, Nuelin, Brondecon) for 24 hours
Cease long-acting nitrates on the day All other medications may be taken as usual up till the day
of the test (Beta-Blockers and Calcium-channel blockers)
Exercise Or Dobutamine Preparation:
Cease Beta-blockers for 48 hours prior (see below for list
Cease Solalol for 72 hours prior Cease Calcium-channel blockers for 24 hours prior (see
below for list o common Calcium-channel blockers)
Cease long-acting Nitrates on the day Continue all other medications
Common Beta-Blockers (Drug name / Generic name): Alprenolol / Aptinª Betacardª Atenolol / Notemª Tenorminª Labetalol / Presalolª Trandateª Metaprolol / Betacaraª Betalocª Lopressorª Minaxª Oxprenolol / Captolª Corbetonª Trasicorª Pindolol / Barblocª Viskinª Practolol / Eraldinª Propanolol / Cardinolª Deralinª Inderalª Prololª Sotolol / Sotocorª Timolol / Blocadrenª Common Calcium-channel blockers (Drug name / Generic
name): Diltiazem / Cardizemª Vasocardolª Felodipine / Agonª Plendilª Adalatª Anpineª Normodipine Perhexiline / Pexidª Verapimil / Ampexª Cordiloxª Isoptinª Veradilª Veracapsª Common Nitrates (Drug name / Generic name): Glyceryl trinitrate / Anginineª Nitrobidª Nitrodiscª Nitrolingual sprayª Transiderm nitroª Isosorbide dinitrate / Isotrateª Isosorbide mononitrate / Imdurª Isosorbide nitrate / Isordilª Pentaerythritol / Peritrateª Common Theophyllines (Drug name / Generic name): Aminophylline / Cardophyllineª Somophyllineª Choline theophyllinate / Brondeconª Choledylª Theophylline / Austinª Elixophyllineª Nuelinª Slo-bidª Theodurª
Gated Heart Blood Pool Scan Bone Densitometry Composition Lung Ventilation / Perfusion Scan
Current chest x-ray (within previous 24 hours)
Nil (Patients should be aware that the scan is performed 3
Gallium Scan
days after injection, and on occasions further scanning is
Investigation of infection and/or inflammation:
Labelled White Blood Cells
Inflammatory bowel disease Diabetic foot
Cease multivitamins and cough medicines for
Cease amiodarone and PTU (or any anti-thyroid
medication) for at least 3 days prior to the study.
Any procedure using iodine-based contrast such as an x-
ray or CT should not be performed 4 weeks prior
Inform department if you use multivitamin tablets, topical
Thyroid Scan And
iodine (e.g. Betadine), and/or have a diet rich in iodine
Radioiodine Therapy
Cease antithyroid tablets (Neomercazole or
Propylthiouracil) for at least 3 days prior.
Contact the department if you have had any of the
following, injections received for x-ray procedures; medicines containing iodine such as Amiodarone,
multivitamin tablets, topical iodine (e.g. Betadine), and/or have a diet rich in iodine (e.g. seaweed) as treatment may need to be deferred
Contact department for radiation related precautions that
must be taken for 10 days after Therapy
Requires admission to Hospital Approximately 6 weeks before treatment cease Thyroxine Approximately 1 week later commence Liothyroninr
Sodium and cease 2 weeks prior to admission
Contact department for further details regarding program
Contact department for radiation related precautions that
Fast 4 hours prior, preferably no longer
Cease morphine or morphine derivatives drugs 24hrs
Gall Bladder / Biliary (HIDA) Scan
If fasting is greater than 4 hours in patients with non-acute
Cholecystitis, the scan may be delayed until 4 hours after consumption of food
Patient should be well hydrated with 4-5 glasses of water
Patients should empty their bladder prior to commencing 1-3 hours
Renal Scan
Cease ACE-inhibitors 2 days prior (see below for list of
Common Calcium-channel blockers (Drug name / Generic
name): Captopril / Capotenª Enalapril / Ampraceª Compraceª Renitecª Fosinopril / Monoprilª Lisinopril / Prinivilª Perindopril / Coversylª Quinapril / Accuprilª Asigª Ramipril / Ramaceª Tritacª
Liver / Spleen Scan Liver Red Blood Cell Cerebral Perfusion (Ceretec) Lymphoscintigraphy
Cease antibiotics or Bismuth containing medicine at least
Carbon-14 Urea Breath Test
Cease Sucrafate at least 2 weeks prior Cease Losec, Nexium, Parier, Probitor, Somac, Zoton at
Sentinel Node Scan Oesophageal Motility Gastric Emptying Salivary Scan GIT Blood Loss
To detect the presence and Preparation:
Parathyroid Scan CSF Studies
localisation and extent of cancerous tissue and their metastatic sites (NHL,
Thallium Tumour
carcinoma and hepatocellular carcinoma), pre or post therapy or for staging
Fast 6 hours, although patient to be well hydrated with
PET/CT Scan
Bring previous x-rays, CT’s, MRI results
Assessment of epilepsy and If diabetic, please contact department
other neurological diseases Please contact department for further information
Patient must first have a MAA Breakthrough Scan under
the same conditions as Therapy performed 1 week prior
The patient is required to be on prophylactic H2
Yttrium-90
The radiopharmaceutical is injected via a trans-femoral
Microspheres
catheter that has been placed into the hepatic artery, after the location of the catheter tip has been confirmed by angiography.
Requires Hospital admission Please contact department for further information
Lugol’s iodine is required; 5 drops 2 twice daily for 2 days
prior to injection and continue for 3 days after injection
Cease anti-depressants, phenothiazines, hydroxizine,
MIBG Adrenal Scan
Cease sympathomimetics (e.g. Sudafed) 1 week prior
Patient is required to attend on several occasions
throughout the week of injection (with scanning at 6, 24 and 48hrs post injection)
Please contact department for further information
Increase fluid intake for 2-3 days post injection
Octreotide Scan
Patient is required to attend on several occasions
throughout the week of injection (with scanning at 6, 24 and 48hrs post injection)
Please contact department for further information
DTPA Lung Clearance
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Category I: Chance-related Heterogeneity Type of presentation: Oral Quantifying the Amount of Heterogeneity in Meta-Analysis: A Comparison of Methods Knapp G Department of Statistics, University of Dortmund, Germany In random effects meta-analysis, several confidence intervals on the between-trial variance have been proposed. These confidence intervals can be broadly categorized in