Efficacy study of styplon vet bolus as supportive therapy in management of hemorrhagic conditions of ruminants
Efficacy study of Styplon Vet Bolus as supportive therapy in management of hemorrhagic conditions of ruminants
Ravikumar B. R1,Mohan D2 and Bhagwat V.G.*3
1- Veterinary Officer, Veterinary Hospital, Mahalakshmipuram, Bagalore.,
2- Veterinary Officer, Veterinary Hospital, Doddagattigenabbe, Hoskote Taluk, Bagalore rural
3- Research Scientist, The Himalaya Drug Company, Makali, Bangalore
Abstract
On-field trial was conducted in dairy animals to evaluate efficacy of Styplon Vet Bolus (M/s Himalaya Drug Company, Banglore, India) as supportive therapy in management of hemorrhagic conditions (Hematuria, hemoagalectia, bleeding wounds, uterine bleeding and epistaxis) of ruminants. Styplon Vet 1-2 boli twice daily was administered to cows and buffaloes, and ½ bolus twice daily for sheep till they recover clinically. The results indicated that Styplon Vet Bolus is a safe and effective styptic in ruminants. Key words: Ruminants, hemorrhagic condition, Styptic. Introduction
were enrolled in the present field trial in and around
Hemorrhage is defined as loss of blood either
the veterinary hospitals of Bangalore district.
within the body (internal) or on the body surface
Table-1. No of ruminant cases enrolled for
(external). Excessive bleeding is a very dangerous
various hemorrhagic conditions
situation that needs attention quickly in animals. The
Conditions Cows Buffaloes
blood flow must be suppressed as soon as possible,
as there is a danger of the animal going into shock.
The causes of bleeding include traumatic injuries (e.g. epistaxis), surgical wounds (cesarian section,
cystotomy), presence of calculi in the urethra or urinary
bladder, infections causing enteritis, cystitis, urethritis,
mastitis, hemoagalectia, hematuria, blood in stools,
Standard managemental practice was followed
etc. Keeping these in view, the present trial was
throughout the trial period. History, clinical signs,
undertaken to assess the efficacy of Styplon Vet Bolus
general health, etc. were recorded for all the animals.
as supportive therapy in management of hemorrhagic
Hemorrhagic condition was diagnosed based on the
conditions like bleeding wounds, hematuria (blood in
history and clinical examinations. Styplon Vet Bolus
urine), hemoagalectia (blood in milk), epistaxis (nasal
(M/s Himalaya Drug Company, Banglore, India) was
bleeding), and uterine bleeding. The Styplon Vet Bolus
administered as supportive (rapid acting styptic/
of The Himalaya Drug Company, Bangalore mainly
coagulating agent) to antibacterial therapy 1-2 boli
contains extracts of Amalaki (Emblica officinalis),
twice daily for cows and buffaloes, and ½ bolus twice
Mocharasa (Bombax ceiba), Vasaka (Adhatoda
daily for sheep till they recover clinically. Time taken
vasica), Sariva (Hemidesmus indicus), Kamala
(in days) for arresting bleeding was recorded. Efficacy
(Nelumbo nucifera), Durva (Cynodon dactylon),
of the therapy was judged based on the clinical
Lajjalu (Mimosa pudica), and powders of Mouktika
recovery and disappearance of clinical symptoms.
sukti, Sourashtri bhasma and Trinakantamani pishti. Materials and methods
Styplon Vet Bolus was used as supportive (rapid
A total of 40 ruminants (30 cows of Jersey,
acting styptic/coagulating agent) to antibacterial
Holstein and non-descriptive breeds, 8 buffales of
therapy in hemorrhagic conditions of ruminants .
Surthi and Murrah breed, and 2 sheep of Bannur breed)
Hematuria cases: Blood in urine ceased in 31.57%
terinary World Vol.2, No.12, December 2009
Efficacy study of Styplon Vet Bolus as supportive therapy in management of hemorrhagic conditions of ruminants
cases in 2 days, in 47.34 % cases in 3 days and in
irritated or inflamed internal tissues. Nelumbo nucifera
21.04 % cases in 4 days respectively on the
administration of Styplon Vet Bolus as supportive
4. Enhancing effectiveness of antibiotics:
It was observed that pearl preparations do not
Hemagalectia cases: Blood in milk had stopped in
show any antibacterial activity but when used at a
50% of cases on each days 2 and 3 of Styplon Vet
concentration of 200 g/ml with antibiotics, then even
Bolus administration along with antibacterials.
at a sub-lethal dose, the antibiotic had effectively
Bleeding wound cases: Both external and internal
shown the results with reduced contact time (11).
wounds were treated with Styplon Vet Bolus. In 75 %
Acknowledgements
of the cases, bleeding from the wound had stopped in
Encouragement provided by The Himalaya Drug
2 days, whereas remaining 25% cases it ceased in 3
Company, Bangalore, for supplying the trial material
days from the administration of Styplon Vet Bolus.
Styplon Vet Bolus for this trial is thankfully
Uterine bleeding cases: On days 2, 3, and 5 of
Styplon Vet Bolus administration, 20 % each of uterinebleeding cases had recovered while in the remaining
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terinary World Vol.2, No.12, December 2009
LOUIS IGNARRO Tutti lo conoscono come “il Nobel del Viagra”, la famosa pasticca blu contro l’impotenza, ma i meriti di Louis Ignarro vanno ben oltre la scoperta che ha portato alla creazione di un singolo farmaco, seppure di fama mondiale. Le sue ricerche hanno aperto la strada allo sviluppo di una classe intera di medicinali: per la cura dell’ipertensione, dello scompenso cardiaco,
GastroMed Suisse Informationen für Grundversorger Juli 2002 Helicobacter pylori Diagnose Die in der Tabel e aufgeführten Tests haben eine Sensitivität (positiver Test bei H.p.- Infizierten) und eine Spezifität (negativer Test bei Nicht-Infizierten) von 90 – 95%. Kosten ** Bemerkungen Resultat * für diesen Test ist eine Endoskopie nötig ** Ungefähre Angabe in CHF