Microsoft word - intramural projects completed_edited_final.doc
HIHT UNIVERSITY NAME OF THE PROJECT PRINCIPAL INVESTIGATOR Year 2008
Effect of Fluoxetines (SSRI) on Urogenital
System of Albino rats Effect of Vigabatrin on central nervous
system of albino rats Effect of dolichos biflorus on blood sugar
and lipid profile levels in streptozotocin
induced diabetic albino rats The influence of the 2:1 yogic breathing
technique on essential hypertension Effect of erogoreflex on respiration in
pulmonary disease To Estimate the levels of blood nitric oxide
in patients with ischemic stroke. Prevalence of and morphological patterns
Diagnostic Utility of Alpha Methylacy1 Coenzyme A racemase (AMACR; P504S)
immunomarker in the carcinoma of prostrate Extended spectrum Beta lactamases and AmpC β-lactamase production in clinical
isolates of (No Suggestions) sp.,E.coli and P.mirabilis. A study on the epidemiological risk factor
and mycological profile of candidemia in
under-5 children Evaluation of various pharmacological
intervention in alcohol dependence Evaluation of various non-conventional
pain Reproductive health needs and determinants of health seeking behavior in
a defined in-migrant population of Dehradun
rural population of Dehradun To Study the clinical patterns and
etiological profile of viral encephalitis Assessment of diastolic dysfunction by
echocardiography and its correlation with
retinopathy in type 2 diabetes mellitus Profile of thyroid functions and thyroid anti
mellitus To study the role of heart rate variability
coherence in coronary artery disease Profile and outcome of acute ischemic
stroke patients Diaphragmatic breathing and systematic
Study of anemia in type2 diabetes mellitus Dr. S.K. Verma Effect of hemodialysis on cardio vascular
nephropathy Anemia in children-a clinico hematological
profile Umbilical cord blood lactate as and early
intrapartum asphyxia Clinical spectrum of flank pain and its
association with urolithiasis The evaluation of prognostic factors in
patients of head injury: Clinical profile of patients with obstructive
jaundice Clinico-pathological profile of salivary
gland tumors Urodynamic study in patients with lumbar
disc prolapse comparative study of extracorporeal shock
wave lithotripsy versus ureteroscopy for
treatment of ureteric calculi Surgical site infection in elective
abdominal surgeries study of clinical profile of lower limb
reconstruction for trauma clinico-radiological study of healing
process of diaphyseal fractures of tibia
treated by interlocking intramedullary nail Evaluation of cephalomedullary implant
fixation in unstable trochanteric fractures. Chondrogenesis in periosteal graft, a long
term follow up-in a rabbit model Evaluation of failure of osteosynthesis in
clinical profile of head and neck malignant
neoplasm Ocular morbidity amongst school going
children role of bevacizumab in posterior segment
ocular diseases comparative study of central corneal
amongst diabetics and non-diabetics Visual field changes in patients with
intracranial space occupying lesions role of magnetic resonance chalangio
pancreatography in evaluation of biliary
and pancreatic diseases role of radio imaging in acute appendicitis
and its clinical correlation role o Computed tomography in acute
Ultrasonography A comparative study on effect of adding
anaesthetics in Brachial plexus block Is I gel a new revolution among available
supraglottic devices- A comparative Study Evaluation of haemodynamic changes
under spinal anaesthsia Comparative evaluation of Neonates delivered by elective caesarean section
anaesthesia with intrathecal opioid (Fentanyl) The role of diagnostic hysteroscopy in
abnormal uterine bleeding Evaluation of urinary tract infection and
asymptomatic bacteriuria in pregnancy Incidence of needle stick injuries during
operations. Profile of thyroid functions in pregnancy
Year 2007
Midgut of Albino Rats Study of Pantoprazole on Gastrointestinal
Mucosa of Albino rats Effect of Curcumin on structure and
motility function of gastrointestinal tract of
albino rats Hepatoprotective effect of curcumin in
albino rats exposed to high environmental
Effect of Curcumin on glucose absorption
from small intestine of albino rats Study of curcumin on amino acids
absorption from small intestine in albino
rats To establish the significance of serum
prognostic tool in cases of CAD To correlate serum bilirubin, calcium &
cholesterol levels with that of bile & Gall
antioxidant status in patients with coronary Dr. A. K. Lal disease Role of Estrogen, Progesterone & HER-
Cancer Study of p53 gene expression in Urinary
Bladder Malignancies Significance of p53 expression in ovarian
tenors HIV prevalence in patients of pulmonary
antigen in HIMS Study of parenterally transmitted Hepatitis
Haemodialysis in a tertiary care hospital Effect of PPAR receptor modulators in CC
induced liver injury Comparative study of efficacy and safety
of various combination therapies used in
moderate persistent bronchial asthma Effect of Angiotensin converting enzyme inhibitors and / or Angiotensin 2 receptor
blockers on insulin resistance in hypertensives An Epidemiological Study of Pulmonary
Tuberculosis in the Field Practice Areas Study of awareness and extent of
Dehradun Assessment of etiological profile and
Clinical profile of Adult Onset Epilepsy
Prevalence of Peripheral Neuropathy in recently diagnosed cases of type 2
diabetes mellitus and its co-relation with nephropathy and retinopathy To Evaluate the Pattern of Neuropathy
patients of Rheumatoid Arthritis Study of pattern of anemia in geriatric
patients of Diabetes Mellitus, Hypertension and Dyslipidemia Evaluation of thyroid functions in patients
of Diabetes mellitus Evaluation of smokeless Tabacco as a
Risk Factor for Essential Hypertension Early Prediction of Steroid
Responsiveness in Nephrotic Syndrome Evaluation of Non specific Markers of
Bronchial Asthama A study of clinical, biochemical and
radiological profile of patients with acute
pancreatitis and its management Endoscopic Third Ventriculostomy Versus
Hydrocephalous A study to determine the prognostic
factors in patients of urolithiasis with
chronic renal failure Clinico-pathological profile of malignant
Study of clinical profile of pressure sores
To study efficacy and safety of fluoroscopy / ultrasound guided
percutaneous nephrostomy in patients with obstructive uropathy To study the clinicopathological profile of
ulcerative colitis Patterns of Treatment Failure in Head and
Neck Squamous cell Carcinomas Role of Anti Cyclic Citrullinated Peptide
The incidence of Deep Vein Thrombosis in patients undergoing surgery for fractures
of lower limb and arthroplasties by duplex ultrasonography Role of locking compression plate in the
articular fractures of proximal part of tibia Correlation of clinical features and MRI
findings in Lumbar Disc Prolapse Clinico-microbiological evaluation of active
tubotympanic type of chronic suppurative
otitis media Clinico-etiological study of Vocal cord
paralysis Role of Fundus Fluorescein Angiography
in Clinically Significant Macular Edema in
Relationship between Intraocular Pressure
Role of Fundus fluorescein angiography in Dr. Harsh Bahadur
Macular diseases Role of Computed Tomography in
neurological disorders of brain in children
Ultrasound with Transrectal Ultrasound in
Prostatic Lesions Comparative study of sevoflurane and Isoflurane anaesthesia in relation to
haemodynamic variations, emergency and recovery in children Comparative study of attenuation of pain caused by propofol intravenous injection
by granisetron, magnesium sulfate and nitroglycerine Induction characteristics and Haemodynamic Alterations during
Propofol Induction : Clinically V/S Bi Spectral Intex guided Role of Digital Video Colposcopy in
Detection of Cervical Lesions Menstrual cycle abnormalities in medical
professional versus non medical females Analysis of maternal and fetal outcome in
pregnant women with liver dysfunction To Study Morbidity and Mortality in Cases
Year 2006
disease. Dermatoglyphics in Type II diabetics
mellitus. Histomorphological study of coronary
artery. Effect of vinca alkaloid, vincristine on
hepatic functions in albino rats. Effect of high altitude on haematological
parameters. A study of haematological parameters and
serum ferritin in blood donors. Effect of vinca alkaloid on gastrointestinal
motility of experimental rats. A comparative study on the ability of urine
to inhibit in vitro mineralization in healthy
and urolithiatic patients. The role of glial fibrillary acidic protein
system lesions. Role of argyrophilic nucleolar organizer
lesion of cervix Study of p53 gene expression in lung
enterococcal isolates. To study the emerging trend in candida
susceptibility patterns To study the efficacy and safety of
gabapentin in post-operative pain, nausea Dr. D.C. Dhasmana and vomiting. Study of efficacy and safety of various
drugs used in acute attacks of migraine. An interventional study amongst anemic
children (1 – 6 years). A study of causes of deaths, using verbal
autopsy, in children below five years in
field practice areas. Rheumatoid arthiritis and macro vascular
disease-A hospital based study. Clinical and biochemical predictors of
meningitis. Anthropometric profile in type-2 diabetics
resistance. To study the clinical profile and risk factors
undergoing coronary angiography. A study of clinical spectrum of extra-
anemia. Study of clinical, radiological and
electrophysiological profile in patients of
meningo-encephalitis. Study of clinico-cardiological profile in
neonatal septicemia. Brainstem auditory evoked response in
neonatal jaundice. A study of pre-operative intra-incisional
antibiotic infiltration for prevention of
surgical site infection. Clinicopathological study of central
nervous system tumors. The study of clinical and radiological
profile in patient of head injury. Etiological factors and clinico-pathological
profile of gall bladder malignancy. The study of diabetic foot and its
management. Clinico-pathological profile of pelvic
malignancies – a hospital based study. Role of aspha-blockers in management of
A study of clinical profile of facio-maxillary
injuries. Experimental posterolateral spinal fusion with Beta tricalcium phosphate ceramic
and bone marrow aspirate composite graft. Transplantation of free tibial periosteal
grafts for the repair of articular cartilage
defect – an experimental study. Evaluation of clinical diagnosis by knee
arthroscopy. Experimental posterolateral spinal fusion using hydroxyapatite, mixed with
autologous bone graft, bone marrow aspirate or collagen. Comparative study of tubotympanic and
atticoantral type of chronic otitis media. Middle ear ossicular chain status in
Specular microscopy of corneal endothelium in diabetic and non diabetic
patients in manual small incision cataract surgery. Study of various parameters for screening
primary narrow angle glaucoma. Specular microscopic study of corneal
diabetics. Evaluation of acute and chronic disorders
imaging (MRI). Diagnostic role of ultrasound and MRI in
hepatobiliary tumors. Evaluation of Retroperitoneal Lesions by
Ultrasonography Efficacy of epidural steroid injection in the
management of pain in intervertebral disc
herniation Variations and outcome of hemodynamic,
oxygen saturation and blood lactate levels Dr. U.C. Sharma in major orthopaedic surgery. Study of Post Dural Puncture Headache with 27 G Quincke and Whitacre Spinal
Needles in Obstetric/Non obstetric patients Study of use of metformin vs. pioglitazone
in polycystic ovarian syndrome. Study of non stress test and Doppler
ultrasound on fetal outcome in high risk
pregnancies. Study of potentially dangerous situations
in HIV infection and remedial measures to Dr. V.P. Singhal prevent its transmission from patients to
doctors. Evaluation of phytoestrongens as therapeutic alternative to hormone
replacemtn therapy in post menopausal women.
Year 2005
“Effect of formalin on respiratory system of
albino rats : a histological study.” “Effects of alternate nostril breathing and
system.: “Study of lateral body positions and
pregnancy.” “Effect of 61 point relaxation training on
syndrome.” “Pulmonary function tests in obese young
adults.” “Study of HbA1c levels and lipid profile in
patients undergoing haemodialysis.” “Study of non-Hodgkin’s lymphoma and its
classification into B or T cell type”. “Comparative study of modified ultrafast
papanicolaou stain in breast lumps.” “Study of HBsAg and HCV, HIV antibody
in blood donors.” “Study of mycological and serological
aspects of pulmonary fungal infections.” “A microbiological study of postoperative
wound infections.” “Comparative antinociceptive evaluation of
anticonvulsants in animal models.” “Study of combination therapies in
epilepsy.” “Study of adolescents health status in a
rural area of Dehradun.” “A study of low birth weight babies and
Dehradun.” “Effects of weather change on evolution
and outcome of acute stroke patients."
“Study of anemia in Rheumatoid Arthritis.” Dr. S.K. Verma “Clinico-electrophysiological co-relation of
mellitus.” “Study of endothelial dysfunction in
“Smoking as a risk factor in tuberculosis
cirrhosis and non-alcoholic hepato steatosis.” “A study of profile and prognosis of non-
traumatic coma.” “Assessment of diastolic dysfunction by
Doppler echocardiography in patients with Dr. Achala Singhal essential hypertension.”
“Study of seizures in children upto 5 years Dr. Lalita Bahl
of age.” “Study of Thyroxine (T4) and Thyroid
newborns.” “Clinical profile and outcome of
perforations.” “Preoperative and perioperative prediction
of difficult laparoscopic cholecystectomy.” “Clinical profile of patients with cleft lip and
palate.” “Study of low and medium pressure
hydrocephalus.” “Correlation of gall stone disease with iron
deficiency anaemia.” “Management of advanced carcinoma
prostate.” “Clinico-pathological profile and
cancer.” “To study the efficacy and complications
of rigid ureteroscopy.” “Evaluation of hydroxypatite and beta tri calcium phosphate ceramic composite
material mixed with bone marrow aspirate
as a bone graft substitute for posterolateral spinal fusion.” “Lumbar discectomy by interlaminar
fenestration technique.” “Results of Intramedullary fixation in
Diaphyseal fractures of forearm bones.” “High tibial osteotomy for medial
compartment osteoarthrosis knee.” “Evaluation of Eustachian tube functions
in otitis media in adults.” “Etiological study of Sensorineural hearing
loss in adults.” “Comparative study of corneal endothelial
cells in cataract surgery.” “Study of surgically induced astigmatism
in manual small incision cataract surgery.” “Role of computed tomography in the
evaluation of lung masses.” “Role of high resolution ultrasonography in
the diagnosis of various thyroid nodules.”
MRI in intracerebral masses.” “Effect of intravenous pantoprazole, ranitidine and metoclopramide on gastric
pH and in obstetrical and non-obstetrical surgeries.” “Temperature monitoring in paediatric
patients during surgery.” “Comparative study of intrathecal opioids (Morphine/Fentanyl/ Sufentanil) and
caesarian sections under spinal anaesthesia.” “Bacterial vaginosis with special reference
to HIV in gynaecological patients.” “Correlation of Endometrial Thickness by transvaginal ultrasonography versus
endometrial biopsy in postmenopausal women.” “A comparative study of ultrasonography
patients with chronic pelvic pain.” “To study the efficacy of newer methods
Year 2004
“Lip prints as a method of identification.”
“Study of Pulmonary functions in young
adults of Garhwal region.” “Peak expiratory flow rate in females in
Garhwal.” “Effects of Isometric and Isotonic
exercises on reaction time.” “To study the effects of lateral positions of
body on autonomic nervous system.” “Study of Microalbuminuria in cases of
hypertension.” “Objective scoring and clinical correlation
of semen quality in fertile and infertile
males.” “Cytodiagnosis of metastasis in lymph
nodes.” “Correlative study of SQUASH smear
lesions.” “Study of incidence of Hospital acquired
“Study of Brucellosis in pyrexic patients.”
“Study of single versus multiple daily
infections.” “Hormone replacement versus alternative
postmenopausal women.” “The prevalence of Sexually Transmitted Diseases (STD) and related health
seeking behaviour among a rural community.” “Cardiac Complications in essential
hypertension.” “Study of Endothelial Dysfunction in
Essential Hypertension.” “Study of Serum Electrolytes in various
Acute poisonings.” “Study of correlation of event related
stress in patients of ischemic stroke.” “Study of Disease pattern in cases of
Pancytopenia.” “Determining the age of menarche and
factors affecting it.” “To study Adenosine Deaminase enzyme
level in CSF in Tuberculous Meningitis.” “Role of diagnostic laparoscopic in
chronic and recurrent pain abdomen.” “Clinico-pathological Profile of Colorectal
Cancer.” “Conserving Surgery for Breast Cancer :
Scope and Limitations.” “Diagnosis and Management of Chest
Trauma.” “Role of Lithotripsy in the management of
Urinary calculi.” “The role of Beta Tricalcium Phosphate
Ceramic as a Bone substitute.” “Study of Retrograde Interlocking nailing
of Distal Femoral Fractures/” “Early detection of hearing loss in
Ototoxicity.” “Audiological profile in safe Chronic
Suppurative Otitis Media (C.S.O.M.).” “Photocoagulatoin v/s surgical excision in
management of Pterygium.” “Photocoagulatory treatment of diabetic
macular edema.” “Doppler evaluation of the extracranial
insufficiency.” “Evaluation of Palpable breast masses by
Mammography and Sonography.” “Temperature and haemodynamic changes during transurethral resection of
prostate under general anaesthesia and regional analgesia.” “Haemodynamic changes in emergency
Misoprostol for induction and augmentation of labor.” “To complete the efficacy of misoprostol
200 ug vs 400 ug for cervical ripening in
Year 2003
“A morphological study of human calcanei
and their articular facets.” “Assessment of physical fitness of young
adults.” “Effect of electromagnetic forces of earth
on human biological system.” “Peak expiratory flow rate in adolescents
of Garhwal region.” “Study of auditory and visual reaction
time in adolescents and young adults.” “Study of microalbuminuria and serum
magnesium in diabetes mellitus.” “Study of thyroid lesions A-cytological and
clinical correlation.” “Anemia and iron status in patients of
gastritis with or without helicobacter pylori
infection.” “Evaluation of lymph node diseases with
Cytology.” “Anti microbial susceptibility pattern among methicillin resistant
with special reference to vancomycin resistance.” “Role of palliative drug therapy in
advanced cancer patients.” “A comparative evaluation of oral
type 2 diabetes mellitus.” “Quality of reproductive and child health
services at primary care level in Dehradun Dr. Surekha Kishore District.” “To study the effectiveness of breath
hypertensives.” “Glucose intolerance in young
hypertensives.” “To study adenosine deaminase enzyme
level in cerebro spinal fluid in tuberculous
meningitis.” “To study the various risk factors for
special reference to homocysteinemia.”
“Endothelial function in diabetes mellitus.” Dr. S.K. Mahajan “A study of low birth weight newborns
ultrasound.” “A study of Glucose – 6 phosphate
hyperbilirubinemia.” “Diagnosis and management of blunt
prospective study.” “Outcome of secondary peritonitis
patients based on APACHE II Score.: “Management of urolithiasis in patients
“Biochemical analysis of gall stones.”
malignancies.” “The role of intramedullary nailing in
treatment of open fractures of the tibia.” “’The role of locked nailing in treatment of
shaft femour.” “Effect of Anterior nasal packing on
capsulotomy : A clinical study.” “Outcome of photocoagulation in diabetic
retinopathy : A clinical study.” “Role of Colour Duppler sonography in
the evaluation of adnexal masses.” “Role of CT Scan in lesions of paranasal
sinuses and nasal cavity.” “Study of presence of nosocomial
infections in association with indwelling
devices in ICU patients”. “Hemodynamic, endtidalcarbon-dioxide saturated pressure of oxygen and
laparoscopic and open cholecystectomy (A clinical evaluation).” “To correlate the clinical and
Year 2002
“Study of Peripheral vascular diseases of
limbs at H.I.M.S.” “To study the effects of Meditation on
coronary artery disease patients” “Evaluation of postoperative visual
outcome and complications after cataract
surgery” “Comparative efficacy and safety of
Neurocystecerosis” “Management of unstable fractures of
lower thoracic and lumber spine by early
stabilization with pedicle screw system” “Morphological and Histopathological
study of placenta in anaemic mothers” “Evaluation of platelet count, total leucocyte count, acute phase reactions
and alloantibiotics in patients undergoing haemodialysis” “A study on prevalence, prophylaxis and treatment of nutritional anaemic in
mothers & children under RCH programme in District Dehradu.” “Colposcopic evaluation of cervical
lesions.” “An anatomico-clinical correlation between
nasal septal deviation and chronic sinus
disease”. “A study of placental morphology and
histology in hypertensive pregnancies and Dr. Sohail A. Perwaiz its correlation with foetal outcome”. “Recovery from cold pressor induced
stress after shavasana in young adults”. “Histopathological changes in gastric
mucosa colonized by helicobacter pylori”. “Study of the morphological pattern of
cytological techniques”. “Study of different diagnostic methods for detection of Helicobacter pylori in patients
dyspepsia / gastritis / peptic ulcer diseases”. “A comparative trial of various non steroidal anti-inflammatory drugs in
rheumatoid arthritis for efficacy and modulation of oxidative stress”. “Study of megaloblastic anaemia in
Himalayan Institute of Medical Sciences”. “The co-relation of duration of diabetes and its complications with serum insulin
level, glycosylated hemoglobin and lipid profile”. “Yoga as an adjuvant therapy in
Rheumatoid Arthritis”. “Clinico-investigative profile of neonatal
septicemia”. “Clinico-pathological study of constrictive
lesions of the gastrointestinal tract in
Himalayan Institute of Medical Scicneces”. “Clinico-patholgoical study of gall bladder
disease in Himalayan Institute of Medical
Sciences”. “Evaluation of outcome of reimplantation of autoclaved tumour bone graft in limb
salvage surgery in Himalayan Institute Medical Sciences, Dehradun”. “Clinico-pathological study of cervical
lymphadenopathy”. “Incidence of retinopathy in diabetic
patients”. “A comparative study of ocular ultrasonic
Garhwal and surrounding plains”. “Evaluation of visual and volumetric changes in temporal lobe epilepsy on
metabolite concentration variation on magnetic resonance spectroscopy”. “Clinico evaluation of blood loss with or
without hypotensive anaesthesia in spinal
surgery”. “Comparative evaluation of haemodynamic changes during insertion
(LMA) and Intubating Laryngeal Mask Airway (ILMA)”. “Torch infections during pregnancy as a
Year 2001
“Estimation of feotal cephalic index in utero during various periods of pregnancy
by ultrasonogram and their correlation to
gestational age in the Garhwali population”. “Evaluation of the sixty-one points
syndrome”. “Éffects of alternate nostril and diaphragmatic breathing on
cardiorespiratory and autonomic functions”. “Peak expiratory flow rate in adult males
of Garhwal”. “Autonomic functional status in
meditators”. “Study of Breast Lesions, a Cytological,
Histopathological and Clinical Correlation”. “To study anaemia profile in patients
coming to Himalayan Institute Hospital”. “Clinicopathologic correlation in
glomerular diseases”. “Characterization and in vitro chemosensitivity pattern of nonfermenting
gram negative bacilli isolated from clinical specimens”.
HIMS”. “An open label, randomized clinical trial to compare the therapeutic profile of conventional antipsychotics haloperidol
antipsychotics, olanzepine and risperidone in treatment of stable schizophrenic patients”. “An open, randomized, placebo controlled clinical trial of alprazolam; and low dose of risperidone, as an adjunctive therapy to
enalapril (as principal drug) in the management of mild to moderate essential hypertension”. “Epidemiological correlates of Fertility and
population of Dehradun District”. “An Epidemiological study of Drug Abuse
among inter-college students of District
Dehradun”. “To study the presentation of various autonomic dysfunctions in patient of type
treatment modalities on autonomic functions”. “A study of various risk factors in patients
of Coronary Artery Disease”. “A study of hematological malignancies at
Himalayan Institute of Medical Sciences,
Dehradun”. “Study of lipid profile in patients of
cerebrovascular accident”. “A clinico-radiological profile of seizure
disorders in children of Garhwal region”. “Tumous of the head and neck region – A
multivariate analysis”. “Clinico-pathological study of bowel
retrospective and prospective study”. “Role of Diagnostic Laparoscopy in
Ascites”. “Evaluation of the role of radiologically assisted percutaneous needle aspiration
biopsy of the spine as an important diagnostic tool”. “Evaluation of surgical treatment in lumbar
“Audiological status in Diabetes Mellitus”.
“Comparative study of visual status after IOL implantation by extra capsular
cataract extraction, non-phaco sutureless cataract surgery and phacoemulsification”.
“Efficacy of topical and systemic intraconazole as a broad spectrum anti-
fungal agent in fungal corneal ulcer : A
“Magnetic Resonance Imaging evaluation
without deliberate hypotension in spinal
“Doppler velocimetery of the uterine artery
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X-ray absorption spectroscopy of single-crystalline „ VO … 2P2O7: Electronic structure and possible exchange paths S. Gerhold, N. Nu¨cker, C. A. Kuntscher,* and S. Schuppler Forschungszentrum Karlsruhe, IFP, P.O. Box 3640, D-76021 Karlsruhe, Germany Naval Research Laboratory, Code 6345, Washington DC 20375 A. V. Prokofiev,† F. Bu¨llesfeld, and W. Assmus Kristall- und Material