Curriculum Vitae Date of Birth: 20/10/1980 Nationality: Iranian Marital Status: Married Address: Department of Medicinal Chemistry, Mobile Phone: +98-918-735-0619 E-mail: [email protected] Education: BSc.: Department of chemistry, Faculty of Science, Razi University, Kermanshah, IRAN (2004). MSc.: Department of chemistry, Faculty of Science, Razi University, Kermanshah, IRAN (2007). Ph.D. Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences,
1. Distinguished researcher in pharmaceutical sciences, fuculty of pharmacy, Isfahan
2. Distinguished researcher in Shamsipur convention in medicinal sciences category (2010).
3. Membership in Talented Assembly of Kermanshah.
4. Membership in Talented Assembly of Isfahan.
5. Participation in establishment of two national standard.
6. Distinguished researcher in pharmaceutical sciences, fuculty of pharmacy, Isfahan
7. Distinguished Ph. D candidate researcher of Isfahan University of Medical Sciences (2010).
8. Distinguished student researcher of Kermanshah university of medical sciences (2010).
9. Distinguished student researcher of Kermanshah University of Medical Sciences (2011).
10. Distinguished Ph. D candidate researcher of Isfahan University of Medical Sciences (2011).
11. Distinguished researcher student in the pharmaceutical sciences part of the 17th razi festival-
12. Distinguished researcher of Kermanshah University of Medical Sciences (2012).
Published Manuscripts: 1. Pourhossein, A*, Madani, M,. Shahlaei, M. Evaluation of an ultrasound–assisted digestion
method for determination of arsenic and lead in edible citric acid samples by ETAAS.
Canad. J. Anal. Scie. Spec. 54 (2009) 39-44. 2. Gholivand, MB., Shahlaei, M., Pourhossein, A. New Zn(II)-Selective Potentiometric Sensor
Based on 3-Hydroxy-2-Naphthoic Hydrazide. SENSOR LETTERS 7 (2009) 119-125. 3. Gholivand, MB.*, Pourhossein, A., Shahlaei, M., Determination of Trace amounts of Lead
by Adsorptive Cathodic Stripping Voltammetry With L-3-(3,4 Dihydroxyphenyl) Alanine,
Collect. Czech. Chem. Commun.74 (2009) 599–610. 4. Gholivand, MB.*, Pourhossein, A., Shahlaei, M., Application of Adsorptive Cathodic
Stripping Voltammetry for Determination of Trace Amounts of Zinc Using Nalidixic Acid
as a Chelating Agent, Chem. Anal. (Warsaw), 54, (2009) 655-666. 5. Shahlaei, M., Gholivand, MB.*, Pourhossein, A. Simultaneous Determination of Tyrosine
and Histidine by Differential Pulse Cathodic Stripping Voltammetry Using H-point Standard
Addition Method in Tap and Seawater, Electroanalysis21(2009) 2499 – 2502. 6. Pourhosseina, A., Madani, M., Shahlaei, M., Fakhri, K., Alimohamadi, P., Amiri, M.
Ultrasound assisted pseudo-digestion for determination of iron and manganese in citric acid
fermentation mediums by electrothermal atomic absorption spectroscopy, Cent. Eur. J. Chem.7(2009) 382-387. 7. Shahlaei, M., Gholivand,MB.*, Pourhossein, A. Application of Adsorptive Stripping
Voltammetry for Determination of Uranium in the Presence of 3-Hydroxy-2-Naphthoic
Hydrazide, Anal. Lett.42 (2009) 3085-3095. 8. Sabet, R, Shahlaei, M., Fassihi, A. QSAR study of anthranilic acid sulfonamides as
inhibitors of methionine aminopeptidase-2 using different chemometrics tools, Recent Advances in Biology, Biophysics, Bioengineering and Computational Chemistry (2009) 119-125. 9. Shahlaei, M., Fassihi, A.*, Nezami, A. QSAR Study of some 5-methyl/trifluoromethoxy-
H-indole-2,3-dione-3-thiosemicarbazone derivatives as antitubercular agents, Research in Pharmaceutical Sciences 4(2009)123-131. 10. Arkan, E., Shahlaei,M., Pourhossein, A., Fakhri, K., Fassihi, A.*, Validated QSAR
Analysis of Some Diaryl Substituted Pyrazoles as CCR2 Inhibitors by Various Linear and
Nonlinear Multivariate Chemometrics Methods. Euro. J. Med. Chem. 45 (2010) 3394- 11. Shahlaei, M., Fassihi, A.*, Saghaie, L. Application of PC-ANN and PC-LS-SVM in QSAR
of CCR1 antagonist compounds:A comparative study. Euro. J. Med. Chem. 45 (2010) 1572–1582. 12. Shahlaei, M., Sabet,R., Bahman Ziari, M., Moeinifard, B., Fassihi, A.*, Karbakhsh, R.
QSAR study of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2
using LS-SVM and GRNN based on principal components, Euro. J. Med. Chem. 45 (2010) 4499-4508. 13. Saghaie, L., Shahlaei, M., Madadkar-Sobhani, A., Fassihi, A.* Application of Partial Least
Squares and Radial Basis Function Neural Networks in Multivariate Imaging Analysis-
Quantitative Structure Activity Relationship: Study of Cyclin Dependent Kinase 4
Inhibitors, J. Mol. Graph. Model, 29 (2010) 518–528. 14. Shahlaei, M., Fassihi, A,*, Saghaie, L., Shamshirian, D., Sakhi, HR. Comparative Quantitative
Structure–Activity Relationship Study of Some 1-Aminocyclopentyl-3- Carboxyamides as
CCR2 Inhibitors using Stepwise MLR, FA-MLR, GA-PLS, In Press, Med. Chem. Res. (2010). 15. Saghaie, L., Shahlaei, M.*, Fassihi, A., Madadkar-Sobhani, A., Gholivand, MB.,
Pourhossein, A. QSAR analysis for some Diaryl Substituted Pyrazoles as CCR2 Inhibitors
by GA-Stepwise MLR, Chem. Biol. Drug Des. 77(2011)75-85. 16. Ayatollahi, AM., Ghanadian, M*, Afsharypuor, S., Choudhary, MI., Abdella, OM., Mohsen Shahlaei, M., Farzandi, G., Mostafavi, H., Cycloartanes from Euphorbia aellenii Rech. f.
with their antiproliferative activity, Iran. J. Pharm. Res. 10 (2011) 105-112 17. Shahlaei, M., , Madadkar-Sobhani, A.*, Mahnama, K., Fassihi, A.*, Saghaie, L.,
Mansourian, M. Homology modeling of human CCR5 and analysis of its binding properties
through molecular docking and molecular dynamics simulation. Biochim. Biophy. Acta- Biomembrane 1808 (2011) 802–817. 18. Shahlaei, M., Fassihi, A*., Saghaie, L., Arkan, E., Pourhossein, A. A modeling study of
aldehyde inhibitors of human cathepsin K using partial least squares method. Research in Pharmaceutical Sciences 6 (2011) 71-80. 19. Fassihi, A.*, Shahlaei, M., Moeinifard, B., Sabet, R. QSAR study of anthranilic acid
sulfonamides as methionine aminopeptidase-2 inhibitors. In Press, Monatshefte fur Chemie 143 (2011) 189-198. 20. Shahlaei, M., Madadkar-Sobhani, A., Fassihi, A*. Saghaie, L. Exploring a Model of a
Chemokine Receptor/Ligand Complex in an Explicit Membrane Environment by Molecular
Dynamics Simulation: The Human CCR1 Receptor. J. Chim. Inform. Model. 51 (2011) 2717-2730. 21. Gholivand, MB.*, Pourhossein, A., Shahlaei, M., Simultaneous determination of copper
and cadmium in environmental water and tea samples by adsorptive stripping voltammetry.
Turk. J. Chem. 35 (2011) 839-846. 22. Shahlaei, M., Fassihi, A*., Saghaie, L., Arkan, E., Madadkar-Sobhani, A., Pourhossein, A.
Computational evaluation of some indenopyrazole derivatives as anticancer compounds;
application of QSAR and docking methodologies. J. Enz. Inhib. Med. Chem. 28(2013) 16- 23. Moradkhani, S., Ayatollahi, AM., Ghanadian, M., Moin, MR., Razavizadehe, M., Shahlaei, M. Phytochemical analysis and metal-chelation activity of Achillea tenuifolia Lam. Iran. J. Pharm. Res. 11(2012) 177-183 24. Shahlaei M., Madadkar-Sobhani, A., Fassihi A., Saghaie, L., Arkan, E. QSAR study of
some CCR5 Antagonists as Anti HIV agents using radial basis function neural network and
general regression neural network on the basis of Principal Components. In Press, Med. Chem. Res. (2011) 25. Shahlaei M., Fassihi A.*, Saghaie L., Arkan E., Pourhossein A. A QSAR study of some
cyclobutenediones as CCR1 antagonists by artificial neural networks based on principal
component analysis, Accepted, DARU 19 (2011) 376-384. 26. Shahlaei M., Madadkar-Sobhani, A., Saghaie, L., Fassihi A*. Application of an expert
system based on genetic algorithm- adaptive neuro-fuzzy interference System (GA-ANFIS)
in QSAR of cathepsin K inhibitors. Inpress, Expert systems with applications 39 (2012) 6182-6191. 27. Saghaie, L., Sakhi, H., Hassan Sabzyan,H.*, Shahlaei,M., Shamshirian D., Stepwise MLR
and PCR QSAR study of the pharmaceutical activities of antimalarial 3-hydroxypyridinone
agents using B3LYP/6-311++G** descriptors. In Press, Med. Chem. Res. 22 (2013)1679- 28. Shahlaie, M.*, Fassihi, A., Pourhossein, A., Arkan, E., Statistically validated QSAR study
of some antagonists of the human CCR5 receptor using least square support vector machine
based on the genetic algorithm and factor analysis. In Press, Med. Chem. Res. 22 (2013) 1399-1414. 29. Shahlaei, M., Ghanadian, SM.*, Ayatollahi, AM, Mesaik, MA., Abdalla, OM.,
Afsharypour, S., Rabbani, M., Molecular modeling, structure activity relationship and
immunomodulatary properties of lupeol derivatives, Med. Chem. Res. 22 (2013)1795- 30. Shahlaei, M.*, Pourhossein, A., Direct determination of arsenic in potassium citrate tablet
using graphite furnace atomic absorption spectrometry, J. Rep. Pharm. Sci, 1(2012) 15-18. 31. Saghaie, L., Shahlaie, M.*, Fassihi, A. Quantitative structure activities relationships of
some 2-mercaptoimidazoles as CCR2 inhibitors using genetic algorithm-artificial neural
networks, Research in Pharmaceutical Sciences 8 (2013) 97-112. 32. Pourhossein, A.*, Shahlaei, M. Direct determination of arsenic in beet sugar molasses using
nickel as chemical modifier by electrothermal atomic absorption spectrommetry 60 (2013) J. Chinese Chem. Soc.241-244. 33. Shahlaei, M.*, Pourhossein, A. A 2D image based method for modeling some c-Src
tyrosine kinase inhibitors Accepted (2012) Med. Chem. Res. 34. Shahlaie, M.*, Fassihi, A. QSAR Analysis of Some 1-(3, 3-diphenylpropyl)-piperidinyl
Amides and Ureas as CCR5 Inhibitors Using Genetic Algorithm- Least Square Support
Vector Machine, Accepted (2012) Med. Chem. Res. 35. Shahlaei, M.* Pourhossein, A. Modeling of CCR5 antagonists as anti HIV agents using
combined genetic algorithm and adaptive neuro-fuzzy inference system (GA–ANFIS),
Accepted (2012) Med. Chem. Res. 36. Maghsoudi, S. Ashrafi, MR.* Shahlaei, M. Ghadami, SA. Ghobadi, S. Mostafaie, A.
Khodarahmi, R*. Comparative Evaluation of Amphotericin B Binding to the Native and
Modified Forms of Rice Lipid-Transfer Protein (LTP1): A Possible Perspective on
Improving the Drug Binding Affinity and Specificity, Accepted (2013) Journal of Iraninan Chemical Society 37. Shahlaei, M.* Zare, A., Saghaie, L., Fassihi, A. Prediction of partition coefficient for
some 3-hydroxy pyridine-4-one derivatives using combined partial least square regression
and genetic algorithm, Accepted (2013) Research in Pharmaceutical Sciences. Presentation of papers in national and international congress Congress Congress Paper title Poster Oral Year National International
یيامد همانرب یزاس هنيھب
هزادنا یارب یتيفارگ هروک
رد زنگنم زيچان ريداقم یريگ
Reviewer of International Journals: Operating System Skills Instrumental Skills:
UV/Visible, Polarogeraph, HPLC, Fluorimeter, Some Skills in Synthesis of organic compounds
Programming Skills Software Skills:
HyperChem, Dragon, Gaussian98, Gaussview, AutoDock, SPSS, Minitab, Chemoffice, web lab
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Mostra tattile L’Ensemble «Allegro ma Cerimonia per i vincitori del premio «Essere cristiani oggi» Padre Miguel Cavallè al Rotary Catania Nord targa ricordo non troppo» al Lyceum L’atteso appuntamento con l’Operetta, nella all’arcivescovo Stagione concertistica 2006-2007 program- mata al Lyceum di Catania dalla presidenteNinfa Ricciardolo, ha visto esibirsi nell’Audito-ri