NUTRITIONAL SUPPORT INCLUDING THE ULTRAGLYCEMX PLUS 360° MEDICAL FOOD PROGRAM IN A PATIENT WITH TYPE 2 DIABETES
Purpose
Initiate exercise plan at 150 minutes/week and
To show how targeted nutritional support featuring
Follow-up with FMRC nutritionist to report
UltraGlycemX (with barley beta-glucans and chlorogenic
progress and adjust dietary/exercise program
acid) and UltraGlycemX PLUS 360° (with SKRMs*) may
be useful in patients with type 2 diabetes.
4-Week Results Patient’s Presentation and History
A 57-year-old Caucasian female presented with a
The patient reported doing well with the LGLD. She was
previous diagnosis of type 2 diabetes. She had a lifelong
eating smaller, more frequent meals and exercising 1
challenge with food cravings, late-night eating, and
hour 5 days/week, plus swimming and yoga 2 to 3
portion control, struggling with weight in high school and
times/week. Fasting blood glucose was still around 120
further after 2 pregnancies (gestational diabetes during
to 128 mg/dL, with 105 to 110 mg/dL at night. She felt
both managed with diet). Weight loss trials had been
better with more energy, but exercise had increased her
unsuccessful; a loss of ~40 lb on a commercial meeting-
arthritis symptoms. Lab tests revealed positive anti-
centered program was regained within a year. A routine
exam 2 years earlier revealed elevated blood glucose
8- through 14-Week Results
(~170 mg/dL) and she was placed on metformin. The dose
was doubled in 6 months, at which time she noted
At the 8-week visit, the patient was doing extremely well
on the LGLD with a total weight loss of 12 lb. After 9 weeks, her fasting blood glucose was ranging 107 to 120
The patient also complained of migraines and joint pain in
mg/dL. She reported a lot more energy and no migraines
her knees, hands, low back, and shoulder. Her medical
since starting the program. Lab tests were positive for
history included recurrent kidney stones, ear infections,
stool gluten sensitivity, and the patient was counseled on
sinusitis (severe), hoarseness, dry mouth, ringing in ears,
gluten elimination. At the 14-week visit, the patient had
bronchitis, and irritable bowel syndrome (IBS). Surgeries
lost a total of 17 lb and reported sustained energy and
included removal of polyps, 2 stereotactic breast surgeries
absence of headaches. Evening glucose measurements
(fibrocystic breasts), and an adenotonsillectomy. She had
continued to improve at ~105 mg/dL. A fall had injured
a family history of heart failure, hypertension, type 2
her back and triggered some IBS-type symptoms.
diabetes, thyroid problems, osteoporosis, and arthritis.
Laboratory tests indicated an increase of hsCRP. The
patient was advised to continue on UltraGlycemX and
Patient’s Objective Information
the gluten-free diet and to add a soluble/insoluble fiber
blend supplement at 1 scoop daily, along with a high
HT: 66”; WT: 224 lb; BP 116/67; BMI: 36.2 kg/m2
potency L. acidophilus/B. lactis combination probiotic, 1
Exercise: yoga 2 times/week; aerobics 2 times/week
18- through 30-Week Results
Prescription medications and supplements included:
levothyroxine sodium (thyroid), 0.50 mg daily;
At 18 weeks, the patient had lost a total of ~21 lb. At the
ezetimibe/simvastatin (cholesterol) 10/20 mg daily;
23-week visit, she noted more energy. Her fasting
triamterene (hypertension), 50 mg daily; lisinopril
glucose had been high at 107 to 127 mg/dL, with 2-hour
(hypertension), 5 mg daily; calcium/magnesium/
postprandial at 105 to 110 mg/dL. She was instructed to
zinc; fish oil; multivitamin/mineral; glucosamine/
replace UltraGlycemX with UltraGlycemX PLUS 360°
Medical Food, 2 scoops twice daily, and continue the
other prescribed nutraceuticals. At 25 weeks, her fasting
glucose had improved with a maximum of 110 mg/dL.
After 30 weeks, these values had sustained.
Conclusion
Begin UltraGlycemX Medical Food, 2 scoops twice
This case study suggests that targeted nutritional support
that combines UltraGlycemX medical foods with LGLD
Begin a Mediterranean-style, low-glycemic-load diet
and aerobic exercise may help show improvement in
clinical symptoms associated with type 2 diabetes.
9% Decrease in Body Weight
After 30 weeks, the patient had a total loss of approximately 20 lb.
A body composition analysis at 14 weeks confirmed an increase in
lean muscle mass and decrease in fat mass. Excess body fat is
associated with an increase in risk to insulin-related disorders
9% Decrease in
The patient’s body mass index (BMI)† was decreased from 36.2
(severely obese) to 33.1 (obese) in 30 weeks on the program.
This result suggests a reduction in risk to lifestyle-related conditions.
13% Decrease in Fasting Glucose
Fasting glucose levels for the patient decreased 17% in 14
weeks to within a normal reference range (65 to 120 mg/dL)
and remained comparable at the 30-week follow-up visit. These results suggest improved glucose metabolism.
* Selective kinase response modulators—or SKRMs—are nutritional substances
Financial support for this study was provided by Metagenics, Inc. This study was
that can work to modulate kinase signaling and may help restore healthy signaling
conducted at the Functional Medicine Research Center (FMRC), the clinical
to genes, favorably affecting genetic expression, and thus helping to reverse some
Case Study: Nutritional Support Including the UltraGlycemX PLUS 360° Medical
†Body Mass Index (BMI) is computed by the weight (kg) divided by the square of
Food Program in a Patient with Type 2 Diabetes. Metagenics, Inc.; 121DM507
the height (m). Note: The information provided in this case study describes the results of one patient under the care of a licensed healthcare practitioner and may not be a typical response. UltraGlycemX and UltraGlycemX PLUS 360° Medical Foods are to be used under the supervision of a physician or other licensed healthcare practitioner.
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