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C/O Sydney Colorectal Associates 37 Gloucester Rd Hurstville NSW 2220 Medal of the Order of Australia in the General Division (2010) Current Appointments: Visiting Medical Officer (1977- ) Clinical Associate Professor UNSW Senior Clinical Advisor NSW Health (2010-) CoChair Strenghtening Local Decision Making Implementation Group NSW Health (2009-) Chair, Governing Council Illawarra and Shoalhaven Local Health Network (2011 - ) Director Division of Surgery St George Hospital Director Division of Critical Care and Surgery St George Hospital John Curtin School of Medical Research (2000- 08) South Eastern Sydney & Illawarra Area Health Service Board of Directors St George Medical Research Foundation Membership of Societies: St. Mark's Association Surgical Research Society of Australia Sydney Colorectal Surgical Society (Foundation Member) Colorectal Surgical Society of Australia (Foundation Member) Journal Associations: Member, Consultant Board, International Journal of Colorectal Disease Reviewer Medical Journal of Australia Reviewer Diseases of the Colon & Rectum President, Sydney Youth Orchestra Association Chairman, Medical Staff Council, St. George Hospital Chairman, St. George Hospital Planning Committee New South Wales Department of Health Oncology Advisory Chairman, Cancer Centre Working Party, St. George Hospital Waiting List and Emergency Department Working Party, Clinical Standards Group, Clinical Costing Project Waiting List Implementation Project, NSW Health Director Special Projects (Clinical Services)(1994-96) Southern Sydney Area Health Service Director MA International - reviews conducted • Clinical Management Structure Auckland General Hospital (1995) • Feasibility study Indonesian National Referral Hospital (for • Surgical Services Alfred Hospital, Melbourne (1997) • Clinical Services Whyalla Hospital (for South Australian Dept Health) • Surgical Services Geelong Hospital (1998) • Clinical Services Albury Base Hospital (for Greater Murray Area • Clinical Services Mid-Western Area Health Service (1999) • Surgical Services Richmond Valley (for Northern Rivers Area Health • Broken Hill Hospital Clinical Services (for Far Western Area Health • ACT Surgical Services (for ACT Health) (2000) • Review Clinical Services Peel AHS (WA) (2001) • Review Operating Theatres Nepean Hospital (2001) • Review Clinical Services Nepean Hospital (with M Gleeson) (2002) • Review Clinical Services Lithgow Private Hospital (2002) • Review Surgical Services Royal North Shore and Ryde Hospitals • Development of Clinical Services Plan Northern Sydney and Central • Review of Clinical Engagement in NSW Health Services – NSW Health • Review Perioperative Service Prince Charles Hospital, Brisbane(2008) • Review Pain Management and Research Service – Royal North Shore Presentations at Scientific Meetings/Abstracts: 1. Surgical Research Society of Australasia Dunedin NZ, 19th September 1987 King D W, Lubowski D Z, Bruck C E. Do patients with haemorrhoids have pelvic floor denervation? (Selected by SRSA for presentation at SRS UK meeting, Bristol, July 1987) 2. Sydney Colorectal Surgical Society Scientific Meeting Orange, 19th March 1988 Lubowski D Z, King D W. What is the best way of measuring external anal sphincter function? 3. Sydney Colorectal Surgical Society Scientific Meeting Orange, 19th March 1988 King D W, Lubowski D Z. The relation between utero-vaginal prolapse and pelvic floor denervation. 4 & 5. Royal Australian College of Surgeons, General Scientific Meeting Brisbane, 4th May 1988 Lubowski D Z, King D W. Do patients with haemorrhoids have pelvic floor denervation? Sigmoid strictures at colonoscopy - an indication for surgery. King D W, Armstrong A, Lubowski D. 6. Royal Australasian College of Surgeons, General Scientific Meeting Brisbane 4th May 1988 Sigmoid strictures at colonoscopy - an indication for surgery. 7 & 8. American Society of Colon and Rectal Surgeons Meeting California, 14th June 1988 Lubowski D Z, King D W, Finlay I G. Failure of contraction of pubococcygeus muscle as a cause of obstructed defaecation. King D W, Lubowski D L, Bruck C E. Do Patients With Haemorrhoids Have Pelvic Floor Denervation? (Poster presentation) 9. Surgical Research Society, Tripartite Meeting (UK SRS, European SRS, Society of University Surgeons), Bristol, UK, 7th July 1988 Lubowski D Z, King D W, Bruck C E. Do patients with haemorrhoids have pelvic floor denervation? 10 Royal Australasian College of Surgeons, NSW State Committee ASM Sydney, 17th September 1988 Beevors M, King D W. Appendicectomy audit. 11. Sydney Colorectal Surgical Society Annual Scientific Meeting Sydney 12th November 1988 Staging - why bother? 12. Sydney Colorectal Surgical Society Scientific Meeting Sydney, 4th February 1989 Colonoscopy - Changing indications. 13. Royal Australasian College of Surgeons Annual Scientific Meeting Melbourne, 10th May 1989 Lubowski D Z, King D W. The pelvic floor in obstructed defaecation 14,15,16. American Society of Colon and Rectal Surgeons Annual Scientific Meeting Toronto, Canada June 1989 King D W, Lubowski D Z. The relationship between utero-vaginal prolapse and pelvic floor denervation Lubowski D Z, King D W, Cook T. Should the anal mucosa be removed in restorative proctocolectomy for ulcerative colitis (poster presentation) Lubowski D Z, King D W. Colon transit in health and constipation assessed using oral I-131 (poster presentation) 17,18.19. Tripartite Meeting (RSM, ASCRS, RACS) Birmingham, UK, 20th June 1989 Lubowski D Z, King D W, Cook T A. Should the anal mucosa be removed in restorative proctocolectomy for ulcerative colitis? King D W, Lubowski D Z, McLean R, Bruck C E, Tallet N A. Colonic transit time determined by radionucleotide imaging in patients with constipation. King D W, Lubowski D Z, Beevors M A, Carlton M A. Pelvic floor function in uterovaginal prolapse (poster presentation) 20. Royal Australasian College of Surgeons Annual Scientific Meeting Sydney, 18th August 1990 Lubowski D Z, King D W, McLean R, Smart R, Gaston-Parry D. Colon transit in health and constipation - analysis of oral In-111 DTPA Awarded State Committee Medal for Best Fellows Paper at ASM 21,22,23,24. Royal Australasian College of Surgeons General Scientific Meeting Sydney, 9th May 1991 Lam T, Lubowski D Z, King D W. Posterior pelvic floor repair for obstructed defaecation. Kooner R, King D W, Lubowski D Z. Faecal incontinence - Selection of patients and results of treatment. Lam T, Lubowski D L, King D W. Does squatting reduce pelvic floor descent and pelvic nerve damage? Morris D L, Dilley A V, Warlters A, Horton M, Clingan P, Tindal D, King D W. Hepatic Cryotherapy for Metastases - Greater Effect of Twin Freeze/Thaw Cycle 25. St. Mark's Association Meeting London, 28th June 1991 Lubowski D Z,King D W, McLean R G, Smart R. Oral In-111 DTPA Scintigraphy: its value for routine clinical assessment of colon transit 26. Academy of Medicine, Silver Jubilee Meeting Singapore, 9th November 1991 Lubowski D Z, King D W, McLean R G, Smart R, Gaston-Parry D. Oral In-111 DTPA Scintigraphy: its value for routine clinical assessment of colon transit in severe constipation 27. American Society of Colon and Rectal Surgeons 5th May1993 Meagher AP, Adams WJ, Lubowski DZ, King DW Autonomic nerves cross the plane of posterior rectal dissection (poster presentation) 28. Sydney Colorectal Surgical Society Scientific Meeting Sydney, 17th July 1993 Topical glyceryl trinitrate in the management of anal fissures. 29,30,31,32,33. Tripartite Colorectal Meeting Sydney, 17-20th October 1993 King D, Adams W, Meagher A, Lubowski D. Pretreatment with bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation. Lubowski D, Meagher A, Sun W, King D. A prospective trial of biofeedback vs placebo for the treatment of anismus Lubowski D, Meagher A, King D, Smart R, Butler P. A scintigraphic study of colonic function during defaecation.(poster presentation) Adams W, Meagher A, Lubowski D, King D. Autonomic nerves cross the plane of posterior rectal dissection.(poster presentation) Lubowski D, Meagher A, King D. Physiological measurement of external sphincter pressure: To squeeze or cough? Lubowski D, Meagher A, King D. (poster presentation) 34.British Society of Gastroenterology Scientific Meeting Manchester 23rd-24th March 1994 Adams W, King D, Lubowski, Morris DL. Cimetidine prevents postoperative Suppression of Immune Function Following Colorectal Cancer Surgery 35,36,37 Royal Australasian College of Surgeons Annual Scientific Meeting Hobart 1st-6th May 1994 Young C, King D, Lubowski D, Jorgensen J Oral Sodium Phosphate Solution is a Superior Preparation to Polyethylene Glycol with Bisacodyl Kennedy M, Lubowski D, King D Glyceryl Trinitrate for Anal Fissure Young C, Kennedy M, Lubowski D, King D Post-anal Repair for faecal incontinence 38,39,40 Surgical Research Society of Australasia Annual Meeting St Vincent’s Clinic Sydney August 1994 Kennedy ML, Lubowski DZ, King DW Chemical Sphincterotomy for Anal Fissure - a new treatment King J, Dasappa VK, Ross WB, King DW, Clingan P, Morris DL Survival of Patients with Synchronous Colectomy & Intrahepatic Chemotherapy Stewart GJ, Preketes AP, Lubowski DZ, King DW, Morris DL Colorectal Cancer Response to High Dose Sandostatin Therapy: A Clinical Trial 41 Sydney Colorectal Surgical Society Thredbo, 12-14 August 1994 Chen FC, Kennedy ML, Lubowski DZ, King DW. Subtotal Colectomy for Slow transit Constipation 42 Sixth National Casemix Conference, Commonwealth Dept of Human Services and Health Hobart 31 August 1994 King DW, Kidd J, Stahel R Clinical Budgeting - The St George Experience 43 Australian Gastroenterology Week (Gastroenterological Society Meeting) Sydney September 1994 Young C, Kennedy ML, Lubowski DZ, King DW Post-anal repair for Faecal Incontinence - long term results (poster) 44 ASM NSW State Committee, Royal Australasian College of Surgeons Pokolbin 10/11 Sep 1994 Young C J, Jorgensen J O, King D W, Lubowski D Z Oral Sodium Phosphate Solution is a superior Colonoscopy Preparation to Ployethylene Glycol with Bisacodyl 45 American Society of Colon and Rectal Surgeons, Washington, June 1996 Talley N A, Chen F, King D, Jones M, Talley N J Short-Chain Fatty Acids in the Treatment of Radiation Proctitis 46. 3rd Australian peptide Conference – From Discovery to Therapeutics – Oct 1998 Burcher E, Warner FJ, Shang F, Markus I, Lubowski DZ, King DW Characterisation and autoradiographic localization of tachkynin receptors in human colon 47. Western Pharmacol. Soc., Maui, USA, Feb 1999 Burcher E, Warner FJ, Shang F, Markus I, Liu L, Lubowski DZ, King DW Tachykinins in human colon 48 American Gastroenterological Association Conference, Atlanta. May 2001 Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King D, Cook IJ Constipation due to obstructed defaecation is likely to be a colonic rather than an anorectal disorder 49 Sydney Colorectal Surgical Society St George Private Hospital 28Jul01 Preoperative CT: selection of patients for combined colon and liver resection or hepatic artery chemotherapy 50. GI Motility Symposium; Murdoch Children’s Research Institute; Royal Children’s Hospital, Melbourne. 20Apr02 Azriel Y, Grimm M. Lubowski D, King D, Burcher E Neurotensin in idiopathic slow transit constipation 51. GI Motility Symposium; Murdoch Children’s Research Institute; Royal Children’s Hospital, Melbourne. 20Apr02 Burcher E, Shang F, liu L, Markus I, King D, Lubowski D Mechanism of tachykinin induced contraction in the human colon 52. American Gastroenterological Association Conference, San Francisco. May 2002 Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King D, Cook IJ Heightened rectal sensory thresholds and blunted recto-colonic motor reflexes implicated in constipation due to obstructed defaecation 53. AHMR, Melbourne, Dec 2002 Azriel Y, Grimm M. Lubowski D, King D, Burcher E Alterations in neurotensin receptors and responsiveness in slow transit constipation 54, 55, 56. Annual Scientific Congress, Royal Australasian College of Surgeons, Brisbane May 2003 Khoo OKS, Kadir A, Balalla B, King DW, Perera DS Abdominal distension and post colonoscopy pain. Schmidt LM, Williams P, Khoo OKS, King DW, Perera DS Oral sodium picosulfate is a superior colonoscopy preparation compared to sodium phosphate Fernando SC, Haghighi KS, Chu F, King J, King DW, Lubowski DZ, Zhao J, Morris DL Synchronous approach to liver metastases from colorectal cancer: Longterm survival and indicators of prognosis after hepatic resection and chemotherapy 57. Australian Gynaecological Endoscopic Surgical Conference 17th May 2003 Thornton MJ, Lam A, King DW Laparoscopic or transanal repair of rectocoele? A retrospective matched cohort study. 58, 59. Australian Gastroenterological Society, Cairns 8th October 2003 Thornton MJ, Kennedy ML, Lubowski DZ, King DW Vaildation of the high frequency wave form demonstrated in the hypertonic anal sphincter: The Fast Wave Thornton MJ, King DW, Lubowski DZ, Cross KM, Glenn D Assessment of the value of the pre-operative abdominal CT in colorectal cancer 60, 61, 62, 63. American Gastroenterological Society, Baltimore, USA, 13th October 10-15, 2003 Thornton MJ, Kennedy ML, Lubowski DZ, King DW Validation of the high frequency wave form demonstrated in the hypertonic anal sphincter: The Fast Wave Journal of Gastroenterology and Hepatology 2003; 18(suppl): A B44 Thornton MJ, Kennedy ML, Lubowski DZ, King DW Long-term follow-up of the dynamic graciloplasty reconstruction for faecal incontinence. Saafan AK, Thornton MJ, Gebski V, Burcher E, Shang F, King DW The prevalence of diverticular disease in patients with slow transit constipation. Journal of Gastroenterology and Hepatology 2003; 18(suppl): A B42 Cosman D, Thornton MJ, Cross KM, King DW, Morris DL Hepatic metastases from colorectal cancer: analysis of morbidity and mortality of synchronous treatment 64. Thornton MJ, Cross KM, King DW, Lubowski DZ, Morris DL Assessment of the value of the preoperative abdominal CT in colorectal cancer Journal of Gastroenterology and Hepatology 2003; 18(suppl): A B4 65, 66, 67. 19th International Symposium on Gastrointestinal Motility, Barcelona, Spain October 5-8, 2003 Burcher E, Shang F, King D, Lubowski D Actions of tachykinin and acetylcholine in human taenia coli: changes in disease Reduction in Neurotensin receptors and neurotensin mediated contractile responses in Slow Transit Constipation. (poster) Azriel Y, Burcher E, Grimm M, Lubowski D, King D The frequency of retrograde colonic propagating sequences may depend on colonic loading. (poster) Dinning P, Cook I, Bampton P, Lubowski D, King D, Kennedy M. 68, 69. Australian College of Surgeons ASC, Melbourne, May 2004. Thornton MJ, Kennedy ML, King DW, Lubowski DZ. Long-term follow-up of the dynamic graciloplasty reconstruction for faecal incontinence. Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients. Thornton MJ, Kennedy ML, King DW. 70, 71, 72. Association of Coloproctology of Britain and Ireland, Birmingham, UK, June 2004. Thornton MJ, Kennedy ML, King DW. Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients. Long-term follow-up of the dynamic graciloplasty reconstruction for faecal incontinence. (poster) Thornton MJ, Kennedy ML, King DW, Lubowski DZ. Validation of the high frequency wave form demonstrated in the hypertonic internal anal sphincter: the Fast Wave. (poster) Thornton MJ, Kennedy ML, King DW, Lubowski DZ. 73. American College of Colon and Rectal Surgery, Philadelphia, USA, April 2005. Thornton MJ, Kennedy ML, King DW. Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients. Invited Presentations: 1. Royal Prince Alfred Hospital, Surgical Guest Lecture. Restorative Proctocolectomy Sydney, 8th March 1988 2. Royal Australasian College of Surgeons CME Programme Flinders Medical Centre, Adelaide, 26th March 1988 Colonoscopy - Normal landmarks; Demonstration 3. Royal Australasian College of Surgeons, Annual Scientific Meeting Brisbane, 3rd May 1988 Pathophysiology of Obstructed Defaecation 4. Gastroenterological Society of Australia, Scientific Meeting Newcastle, 7th October 1989 Surgical management of constipation. 5. Royal Australian College of Medical Administrators Sydney, 1st November 1990 The Organisation of Health Services in the 1990’s 6. Royal Australasian College of Surgeons General Scientific Meeting Sydney, May1991 Colonoscopy Workshop: Technique and Demonstration 7. Royal Australasian College of Surgeons CME Programme Brisbane, 1991 Surgical management of rectal prolapse 8. Royal Australian College of Medical Administrators Sydney, 28th May 1992 The Organisation of Health Services in the 1990's - A Clinical Divisional View 9,10. University of Wollongong Graduate School of Health and Medical Sciences Sydney, June 1993 The Australian Health Care System: Policy and Politics "Who Makes the rules" "Professions in Transition" 11. Community Health Forum, Eastern Area Health Service Sydney, 27th August 1993 Acute Health Homecare: Budgets and Cost Effectiveness 12.Clinical Budgeting Workshop Policy and Planning Branch, Queensland Health Brisbane,16Sep94 13.Executive Education Seminars SSAHS 25Jul94 “Strategic Directions in Health Care” 14. National Programme of Management Development for Australian Clinicians Melbourne 24-25Nov94 “Management is not Administration” 15. “Clinical Management” Toowoomba Hospital Toowoomba 13Feb95 16. “The Relevance of Costing and Clinical Budgeting to Clinicians” “Economics of Health Care” “Information Systems and Clinical Management” Prince Charles Hospital, Brisbane, 25May95 17. “Best Practice - NDHP Perspective NSW Health Best Practice Seminar Sydney 07Aug95 18. “Motivating Doctors for Cultural Change” AHA Congress 95 Adelaide, 27Oct95 19. “The Future of Large Teaching Hospitals” Orientation Program for NSW Health Directors Sydney, 16Aug96 20. “The Difficult Polyp” RACS Section of Colorectal Surgery CME Conference/Sydney Colorectal Surgical Society Sydney, 09Nov96 21. “Quality in Australian Health Care” World Bank study tour Sydney, Feb97 22. “Colonoscopic screening: how often is too often?” ASM Sydney Colorectal Surgical Society Sydney Nov99 23. “Screening tests for bowel cancer and investigaying bowel symptoms NSW Cancer Council and St George Division of General Practice 28th August 2001 24. “Chronic constipation following pelvic surgery’ Pelvic Floor Symposium, Australian Gynaecological Endoscopy Society 14th September 2001 25. ‘Screening tests for bowel cancer” Prevention, Screening and Familial Aspects of Bowel Cancer The Cancer Council, NSW 29th August 2001 26. “Synchronous treatment of primary and secondary colorectal cancer – The St George experience” St George Liver Oncology Group 19th October 2003 27. “Recent advances in Colorectal Cancer” Gujarat Cancer and Research Institute, Ahmedabad, India 31st May 2004 28. Screening colonoscopy- indications Royal Australasian College of Surgeons CME Programme September 2004 Publications - Original Articles: 1. Brooke B N, Cave D R, King D W. The place of Azathioprine for Crohn's Disease Lancet 1976; 1041-42 2. King D W. Melaena due to ectopic pancreas in enteric duplication - a case report Singapore Medical Journal 1976, 17:56-57 3. Hanel K C, King D W, McAllister E T, Reiss-Levy E. Single-dose Parenteral Antibiotics as Prophylaxis Against Wound Infections in Colonic Operations Diseases of the Colon and Rectum 1980, 23:98-101 4. King D W, Lubowski D Z, Talley N A, Pryor D S. Restorative proctocolectomy with ileal reservoir and ileoanal anastomosis - a clinico-physiological study. Aust NZ J Surg 1987; 57:555-558 5. Bruck C E, Lubowski D Z, King D W. Do patients with haemorrhoids have pelvic floor denervation? International J Colorectal Dis 1988; 3:210-214 6. Lubowski D Z, King D W Recto-anal reflex after rectal excision. Br J Surg 1988; 75:1150 (letter) 7. King D W, Lubowski D Z, Cook T A. Anal canal mucosa in restorative proctocolectomy for ulcerative colitis. Br J Surg 1989; 76: 970-972 8. McLean R G, Smart R C, Gaston-Parry D, Barbagallo S, Baker J, Lyons N R, Bruck C E, King D W, Lubowski D Z, Talley N A. Colon transit scintigraphy in health and constipation using oral I-131 cellulose. J Nuclear Med 1990; 31:985-989 9. King D W, Lubowski D Z, Armstrong A S. Sigmoid stricture at colonoscopy - an indication for surgery. International J Colorectal Dis 1990; 5:161-163 10. Beevors M A, Lubowski D Z, King D W, Carlton M A. Pudendal nerve function in women with symptomatic utero-vaginal prolapse. International J Colorectal Dis 1991; 6:24-28 11. Smart R C, McLean R G, Gaston-Parry D, Barbagallo S, Bruck C E, King D W, Lubowski D Z, Talley N A. Comparison of I-131 cellulose and I-111 DTPA as tracers for colon transit scintigraphy - analysis by colon activity profiles. J Nuclear Med 1991; 32:1668-1674 12. Lubowski D Z, King D W Faecal Incontinence (review article) The National Continence Newsletter, Continence Foundation, No VAW8179 p14 1991 13. Lubowski D Z, King D W, Finlay I G. Electromyography of the pubococcygeus muscles in patients with obstructed defaecation. International J Colorectal Dis 1992; 7:184-187 14. McLean R, Smart R C, Lubowski D Z, King D W, Barbagallo S, Talley N A. Oral colon transit scintigraphy using indium-111 DTPA: variability in healthy subjects. International J Colorectal Dis 1992; 7:173-176 15. Merrett N D, Lubowski D Z, King D W. Torsion of the vermiform appendix: a case report and review of the literature. Aust NZ J Surg 1992; 62:981-983 16. Lubowski DZ, King DW, Lam TCF. Surgical Management of Anal Incontinence Annals Academy of Medicine, Singapore 1992; 21:280-283 17. Jorgensen J, Stein P, King D W, Lubowski D Z. The anorectal angle is not a reliable parameter on defaecating proctography. Aust NZ J Surg 1993; 63:105-108 18. Lam T C F, Islam N, Lubowski D Z. King D W. Does squatting reduce pelvic floor descent during defaecation? Aust NZ J Surg 1993; 63:172-174 19. Meagher AP, Lubowski DZ, King DW. The cough response of the anal sphincter Intnl J Colorectal Dis 1993, 8:217-219 20. Salaman JR, Griffin PJ, Ross WB, Lubowski DZ, King DW, Peters L, Nour R, Quinn RJ, Morris DL, Butler SP Avid thallium uptake in hepatic carcinoid metastases Eur J Nucl Med 1993; 20(9); 804-6 21. Adams W J, Meagher A P, Lubowski D Z, King D W. Bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation. Dis Colon Rectum 1994;37;229-234 22. Adams WJ, Morris DL, Ross WB, Lubowski DL, King DW, Peters L Cimetidine preserves non-specific immune function after colonic resection for cancer Aust N Z J Surg 1994;34;847-852 23. Young C, Kennedy ML, Lubowski DZ, King DW Post-anal Repair for Faecal Incontinence - long term follow-up Journal of Gastroenterology and Hepatology 1994;9;A113 24. Lubowski DZ, King DW Obstructed Defecation: Current Status of Pathophysiology and Management Aust. N.Z.J. Surg. (1995) vol65, 87-92 25. McLean R, Smart R, Barbagallo S, King D, Stein P, Talley N Colon Transit Scintigraphy Using Oral Indium-111-Labelled DTPA. Can Scan Pattern Predict Final Diagnosis? Digestive Diseases and Sciences, (1995) vol40, 2660-2668 26. Dasappa V, Ross WB, King J, King DW, Clingan PR, Morris DL Primary resection and synchronous regional hepatic chemotherapy or cryotherapy for colorectal cancer with liver metastases. Intnl J of Colorectal Disease 1996;11;nr1;38-41 27. Brookes SJH, Lam TCF, Lubowski DZ, Costa M, King DW Regeneration of nerves across a colonic anastomosis in the guinea-pig Journal of Gastroenterology and Hepatology (1996) vol11, 325-334 28. Kennedy ML, Nguyen H, Lubowski DZ. King DW Stimulated gracilis neosphincter: A new procedure for anal incontinence Aust. N.Z.J. Surg. (1996) vol66, 353-357 29. Lubowski DZ, Chen FC, Kennedy ML, King DW Results of colectomy for severe slow transit constipation Dis Colon Rect 1996; 39:23-29 30. Talley NA, Chen FC, King DW, Jones M, Talley NJ Short-Chain Fatty Acids in the Treatment of Radiation Proctitis Dis Colon Rect 1997; 40:1046-1050 31. McLean RG, King DW, Tallet NA, Tait AD, Frieman J The Utilization of Colon Transit Scintigraphy in the Diagnostic Algorithm for Patients with Chronic Constipation Digestive Dis and Sciences 1999; 44:1;41-47 32. Finlay IG, Dwerryhouse SJ, King J, King DW, Lubowski DZ, Morris DL The effect of a short preoperative course of cimetidine on the grade of TIL in primary colorectal cancer - a randomised controlled clinical trial GI Cancer (1999) vol3, 121-127 33. Kelly M, King J, Cherian M, Dwerryhouse S, Finlay I, Adams W, King DW, Lubowski DZ, Morris DL Randomised trial of preoperative cimetidine in patients with colorectal cancer with quantitative assessment of tumour - associated lymphocytes Cancer (1999) vol 85, 1958-63 34. Horsell KW, Merten S, Clingan PR, King DW, Morris DL Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer Aust NZ J Surg (1999) 69:729-32 35. Young CJ, Simpson RR, King DW, Lubowski DZ Oral sodium phosphate is a superior colonoscopy preparation to polyethylene glycol with bisacodyl Dis Colon Rectum 2000; 43:1568-1571 36. S Chew, King DW Use of Endoscopic Titanium Stapler in Rectal Anastomotic Stricture Dis Colon Rectum 2002;45;283-285 37. M L Kennedy, D Z Lubowski, D W King Transanal Endoscopic Microsurgery. Is Anorectal Function Compromised? Dis Colon Rectum 2002;45;601-604 38. L Schmidt, P Williams, D King, S Perera Picoprep-3 is a superior colonoscopy preparation compared to Fleet Dis Colon Rectum 2004;47(2);238-242 39. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King DW, Cook IJ Abnormal predefecatory colonic motor patterns define severe constipation in obstructed defecation Gastroenterology 2004;127(1):49-56 40. Wong SW, King DW Surgical Techniques; Sutureless Intestinal Plication ANZ J Surg 2004;74(8):681-83 41. Thornton MJ, Kennedy ML, King DW, Lubowski DZ Long-term follow-up of dynamic graciloplasty for faecal incontinence Colorectal Disease 2004;6:470-76. 42. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ. King DW, Cook IJ. Abnormal predefecatory colonic motor patterns define constipation in obstructed defecation. Gastroenterology 2004; 127:49-58 43. Thornton MJ, Kennedy ML, King DW,Lubowski DZ. The High Frequency Wave Form (Fast Qave) in the hypertonic internal anal sphincter. Validation of a new observation. Colorectal Disease 2004; 6(suppl 1): 69 44. Thornton MJ, Lam A, King DW Laparoscopic or pelvic floor repair of rectocoele? A retrospective matched cohort study. Dis Colon Rectum 2005;48:792-98 45. Thornton MJ, Lam A, King DW Bowel, bladder and sexual function in women undergoing laparoscopic posterior compartment repair in the presence of apical or anterior compartment dysfunction. Aust NZ J Obstet Gynaecology 2005;45:195-200 46. Thornton MJ, Kennedy ML, King DW Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients. Dis Colon Rectum 2005;48(7):1424-31 (Paper awarded Mark Killingback Prize for Colorectal Research at the ANZCS ASC Melbourne May 2004) 47. Thornton MJ, Kennedy ML, King DW Manometric assessment of acute anal fissure and physiological effect of topical glyceryl trinitrate – prospective trial Dis Colon Rectum 2005;48960: 1207-12 48. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King DW, Cook IJ Impaired proximal colonic motor response to rectal and chemical stimulation in obstructed defecation. Dis Col Rectum 2005; 48(9): 1777-1784 49. Thornton MJ, Kennedy ML, King DW, Lubowski DZ Electromagnetic stimulation of the Pelvic Floor for idiopathic faecal incontinence: effect on anorectal physiology Dis Colon Rectum 2005;38(10):1945-50 50. Thornton MJ, Lubowski DZ, Kennedy ML, King DW Faecal Incontinence, a multifactorial problem. (submitted for publication) 51. Dinning PG, Fuentealba SE, Kennedy ML, Lubowski DZ, King D, Cook IJ. Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defaecation frequency in patients with slow transit constipation. Colorectal Dis 2007; 9(2):123-32 52. Yan TD, Chu F, Black D, King DW, Morris DL Synchronous Resection of Colorectal Primary Cancer and Liver Metastases World J Surg (2007) 31:1496-1501 53. Nielsen HJ, Brunner N, Frederiksen C, Lomholt AF, King DW, Jorgensen LN, Olsen J, Rahr HB, Thygesen K, Hoyer U, Laurgerb S, Christensen IJ Plasma tissue inhibitor of metalloproteinases-1 (TIMP-1): A novel biological marker in the detection of primary colorectal cancer. Protocol outlines of the Danish-Australian endoscopy study group on colorectal cancer detection Scandinavian Journal of Gastrolenterology (2007) (accepted for publication) 54. Mackey P, King D, Lubowski D Post-anal repair. Do the long-term results justify the procedure? Colorectal Disease 2008 (accepted for publication) 55. Burcher E, Shang F, Warner FJ, Du Q, Lubowski DZ, King DW, Liu L Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomethacin and in diverticualr disease and ulcerative colitis. J Pharmacol Exp Ther. 2008 324:170-178 56. Liu L, Markus I, El Saghire H, Perera D, King D, Burcher E Tachykinin gene expression in human smooth muscle and mucosa: disctinct differences in ulcerative colitis, Crohn’s disease and diverticular disease. American Journal of Physiology (accepted for publication 18Nov09) 57. Liu L, Shang F, Morgan MT, King DW, Lubowski DZ, Burcher E. Cyclooxygenase-dependent alterations in substance P-mediated contractility and NKI receptor expression in the colonic circular muscle of patients with slow transit constipation J Pharmacol Exp Ther. 2009 329:282-289 58. Dinning PG, Jones M, Fuentealba SE, Kalanter K, King DW, Lubowski DZ, Talley NJ, Cook IJ. Factor analysis identifies subgroups of constipation. World J Gastroenterol. 2011. 17(11): 1468-74 Review Articles: 1. Lubowski D Z, King D W. Faecal Incontinence. The National Continence Newsletter, Continence Foundation, No. VAW8179, pp14, 1991 2. Lubowski D Z, King D W, Lam T C F. Surgical management of anal incontinence. Annals Academy of Med, Singapore 1992; 21:280-283 Monographs and Book Chapters: 1. Brooke B N, Cave D A, Gurry J F, King D W. Crohn's Disease Pub. Macmillans London 1976 2. Lam T C F, Lubowski D Z, King D W. Solitary Rectal Ulcer Syndrome In: Clinical Gastroenterology. Vol: Anorectal Disorders (Henry MM, Ed.) Bailliere Tindall/ W B Saunders, London, 1992, Vol 6/1, pp129-143 3. Meagher A P, Adams W J, Lubowski D Z, King D W. Anatomy of Rectum and Anus. In: Colorectal Physiology: Fecal Incontinence (Kuijpers H C, Ed.) CRC Press, Florida, 1994 4. King DW Colorectal Cancer In: Cancer: A Comprehensive Clinical Guide (Morris et al, Ed) Harwood Academic Publishers, 1998 Publications – Abstracts/Letters: 1. King D W, Lubowski D Z, Bruck C E. Do patients with haemorrhoids have pelvic floor denervation? Aust NZ J Surg 1988; 58:243 2. Lubowski D Z, King D W, Bruck C E. Do patients with haemorrhoids have pelvic floor denervation? Br J Surg 1988; 75:1269-1270 3. McLean R, Gaston-Parry D, Smart R, Barbagallo S, Baker J, Lyons N, King D W, Lubowski D Z. Oral In-111 DTPA: Its value for routine clinical assessment of colon transit. J Nuclear Med 1989; 30:887 4. McLean R, Gaston-Parry D, Smart R, Barbagallo S, Baker J, Lyons N, King D W, Lubowski D Z. Colon transit in health and constipation assessed using I-131 cellulose. J Nuclear Med 1989; 30:764-765 5. Smart R, McLean R, Willson J, Barbagallo S, Gaston-Parry D, Lyons N, Lubowski D Z, King D W, Bruck C E. Colon transit in health and constipation: analysis using colon activity-profiles. ANZ J Med 1990; Suppl 1:445 6. Smart R, McLean R, Wilson J, Barbagallo S, Gaston-Parry D, Lyons N, Lubowski D Z, King D W, Bruck C E. The assessment of colon transit in adults using In-111 DTPA and colon activity profiles. Europ J Nuclear Med 1990; 16(suppl):S319 7. McLean R, Smart R, Lubowski D Z, King D W, Bruck C E. Colon transit scintigraphy - normal ranges and variability in normal subjects. ANZ J Med 1991; 21:633 8. McLean R, Smart R, Lubowski D Z, King D W, Stein P. Colon transit scintigraphy in idiopathic constipation - can scan patterns predict pathology? ANZ J Med 1991; 21:633 9. Lubowski D Z, King D W, McLean R G, Smart R, Gaston-Parry D. Oral In-111 DTPA scintigraphy: its value for assessment of colon transit in severe constipation. ANZ J Surg 1991; 10. McLean R G, Smart R C, Lubowski D Z, King D W, Bruck C E. Colon transit scintigraphy: normal ranges and variability in normal subjects. Aust NZ Soc Nucl Med 1991; 67 11.Adams WJ, King DW, Lubowski DZ, Morris DL Cimetidine prevents postoperative suppression of immune function following colorectal cancer surgery Gut 1994; 35:S16 12. Young C, Kennedy M, Lubowski DZ, King DW Postanal repair for faecal incontinence - long-term results J Gastroenterol Hepatol 1994; 9:A113 13. Lubowski DZ, Kennedy M, King DW Chemical sphincterotomy for anal fissure - a new treatment Aus NZ J Surg 1995; 65:423 14. Adams WJ, Meagher AP, Lubowski DZ, King DW Bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation Gastroenterol Digest, May 1995; 15-16 15. Stewart GJ, Preketes AP, Lubowski DZ, King DW, Morris DL Colorectal cancer response to high-dose sandostatin therapy: A clinical trial Aust NZ J Surg 1995; 65:435 16. Burcher E, Warner FJ, Shang F, Markus I, Liu L, King DW, Lubowski DZ Characterisation and autoradiographic localisation of tachykinin receptors in human colon 3rd Australian Peptide Conference – From discovery to Therapeutics; Oct 1998 17. Burcher E, Warner FJ, Shang F, Markus I, Liu L, King DW, Lubowski DZ Tachykinins in the human colon Western Pharm Soc Maui, USA; Feb 1999 18. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King DW, Cook IJ. Constipation due to obstuted defaecation is likely to be a colonic rather than an ano-rectal disorder. Gastroenterology 2001:125(5)(Supl1);A751. (Presented American Gastroenterological Association cinference, Atlanta May 2001) 19. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King DW, Cook IJ Heightened rectal sensory thresholds and blunted recto-colonic motor reflexes implicated in constipation due to obstructed defaecation. Gastroenterology 2002; 122(4) A316. (Poster presentation at AGA Conference, San Francisco, May 2002) 20. Azriel Y, Grimm M, Lubowski DZ, King DW, Burcher E. Alterations in neurotensin receptors and responsiveness in slow transit constipation AHMR Melbourne, Dec 2002; Proc Aust Health Med Res Congress 2002 21. Thornton MJ, Kennedy ML, Lubowski DZ, King DW Long-term follow-up of Dynamic Graciloplasty for Faecal Incontinence Am J Gastroenterology 2003;29(9 suppl) S1-339 22. Thornton MJ, Kennedy ML, King DW, Lubowski DZ. The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation of a new observation. Am J Gastroenterology 2003;29(9 suppl) S1-339 23. Cosman D, Thornton MJ, Cross KM, King DW, Morris DL. Hepatic metastasis from colorectal cancer: analysis of morbidity and mortality of synchronous treatment. Am J Gastroenterology 2003;29 (9 suppl) S1-339 24. Thornton MJ, Kennedy ML, King DW Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients. Colorectal Dis 2004;6(suppl 1):30 25. Thornton MJ, Kennedy ML, King DW Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients ANZ J Surg 2004; 74 (Suppl) A34-A41 (CR21) 26. Thornton MJ, Kennedy ML, Lubowski DZ, King DW Long-term follow-up of Dynamic Graciloplasty for Faecal Incontinence ANZ J Surg 2004; 74 (Suppl) A30-A41 (CR 25) 27. Thornton MJ, Kennedy ML, Lubowski DZ, King DW Long-term follow-up of Dynamic Graciloplasty for Faecal Incontinence Colorectal Dis 2004;6(suppl 1):68 (P096) Am J Gastroenterology 2003;29 (9suppl) S1-339 28. Phan-Thien K-C, Perera DS, King DW Patient Compliance with Recall Colonoscopies – What is Good Enough? ANZ J Surg. 2004; 74 (Suppl) A35 29. Thornton MJ, Lam A, King DW Laparoscopic or transanal repair of rectocele? A retrospective matched cohort study. ANZ J Surg 2004;74 (Suppl) A30-A41 (CR 42P) 30. Thornton MJ, Kennedy ML, King DW, Lubowski DZ. The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation of a new observation. Colorectal Dis 2004;6(suppl 1):69 (P098) 31. Thornton MJ, Kennedy ML, King DW, Lubowski DZ. The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation of a new observation. J Gastroenterology & Hepatology 2004;18(suppl):B44 32. Thornton MJ, Kennedy ML, King DW, Lubowski DZ. The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation of a new observation. ANZ J Surg 2004; 74 (Suppl) A30-A41 (CR 41P) Am J Gastroenterology 2003;29 (9suppl) S1=339 33. Burns HL, Thornton MJ, King DW. Pre-existing pelvic floor dysfunction prior to transanal rectocele repair: a retrospective analysis. ANZ J Surg 2004;74 (suppl) A30-A41 (CR 52P) 34. Thornton MJ, Cross KM, King DW, Lubowski DZ, Morris DL. Assessment of the value of the pre-operative abdominal CT in colorectal cancer. J Gastroenterology & Hepatology 2004;18(suppl):A B4 35. Saafan AK, Thornton MJ, Gebski V, King DW. The prevalence of diverticular disease in patients with slow transit constipation. J Gastroenterology & Hepatology 2003;18(auppl):A B42 Am J Gastroenterology 2004;29 (9 suppl) S1-339 36. Byrne CM, Perera DS, King DW Does rectal washout during anterior resection prevent local tumour recurrence? Dis Colon Rectum 2005;48L172-4 37.Thornton MJ, Lam AM, King DW. Bowel, bladder and sexual function in women undergoing laparoscopic posterior compartment repair in the presence of apical or anterior compartment dysfunction. Aust N Z J Obstet Gynaecol. 2005;45:195-200 Research Grants obtained: NHMRC grant 157134. 2001-2003. Associate Investigator Motor patterns of colonic transit and pathophysiology of severe constipation. NHMRC grant 222739. 2002-2005. Associate Investigator Neurochemicals and neuromodulators in human intestine: changes in disease. NHMRC 568861. 2009-2011. Associate investigator Hemokinin – a new inflammatory mediator in the intestine Postgraduate students supervised: M J Thornton: MD (UNSW) 2005 – Benign Anorectal Disorders V Patton: PhD (UNSW) 2010 – Constipation and Incontinence

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